PGC1 beta (PPARGC1B) (NM_001172699) Human Untagged Clone

CAT#: SC329232

PPARGC1B (untagged)-Human peroxisome proliferator-activated receptor gamma coactivator 1 beta (PPARGC1B) transcript variant 3

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: PPARGC1B
• Synonyms: ERRL1; PERC; PGC-1(beta); PGC1B
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_001172699, the custom clone sequence may differ by one or more nucleotides
  ATGGGTGGAGGGTCCGGGGAGGAGCAACTCTATGCTGACTTTCCAGAACTTGACCTCTCC
  CAGCTGGATGCCAGCGACTTTGACTCGGCCACCTGCTTTGGGGAGCTGCAGTGGTGCCCA
  GAGAACTCAGAGACTGAACCCAACCAGTACAGCCCCGATGACTCCGAGCTCTTCCAGATT
  GACAGTGAGAATGAGGCCCTCCTGGCAGAGCTCACCAAGACCCTGGATGACATCCCTGAA
  GATGACGTGGGTCTGGCTGCCTTCCCAGCCCTGGATGGTGGAGACGCTCTATCATGCACC
  TCAGCTTCGCCTGCCCCCTCATCTGCACCCCCCAGCCCTGCCCCGGAGAAGCCCTCGGCC
  CCAGCCCCTGAGGTGGACGAGCTCTCACTGGCGGACAGCACCCAAGACAAGAAGGCTCCC
  ATGATGCAGTCTCAGAGCCGAAGTTGTACAGAACTACATAAGCACCTCACCTCGGCACAG
  TGCTGCCTGCAGGATCGGGGTCTGCAGCCACCATGCCTCCAGAGTCCCCGGCTCCCTGCC
  AAGGAGGACAAGGAGCCGGGTGAGGACTGCCCGAGCCCCCAGCCAGCTCCAGCCTCTCCC
  CGGGACTCCCTAGCTCTGGGCAGGGCAGACCCCGGTGCCCCGGTTTCCCAGGAAGACATG
  CAGGCGATGGTGCAACTCATACGCTACATGCACACCTACTGCCTCCCCCAGAGGAAGCTG
  CCCCCACAGACCCCTGAGCCACTCCCCAAGGCCTGCAGCAACCCCTCCCAGCAGGTCAGA
  TCCCGGCCCTGGTCCCGGCACCACTCCAAAGCCTCCTGGGCTGAGTTCTCCATTCTGAGG
  GAACTTCTGGCTCAAGACGTGCTCTGTGATGTCAGCAAACCCTACCGTCTGGCCACGCCT
  GTTTATGCCTCCCTCACACCTCGGTCAAGGCCCAGGCCCCCCAAAGACAGTCAGGCCTCC
  CCTGGTCGCCCGTCCTCGGTGGAGGAGGTAAGGATCGCAGCTTCACCCAAGAGCACCGGG
  CCCAGACCAAGCCTGCGCCCACTGCGGCTGGAGGTGAAAAGGGAGGTCCGCCGGCCTGCC
  AGACTGCAGCAGCAGGAGGAGGAAGACGAGGAAGAAGAGGAGGAGGAAGAGGAAGAAGAA
  AAAGAGGAGGAGGAGGAGTGGGGCAGGAAAAGGCCAGGCCGAGGCCTGCCATGGACGAAG
  CTGGGGAGGAAGCTGGAGAGCTCTGTGTGCCCCGTGCGGCGTTCTCGGAGACTGAACCCT
  GAGCTGGGCCCCTGGCTGACATTTGCAGATGAGCCGCTGGTCCCCTCGGAGCCCCAAGGT
  GCTCTGCCCTCACTGTGCCTGGCTCCCAAGGCCTACGACGTAGAGCGGGAGCTGGGCAGC
  CCCACGGACGAGGACAGTGGCCAAGACCAGCAGCTCCTACGGGGACCCCAGATCCCTGCC
  CTGGAGAGCCCCTGTGAGAGTGGGTGTGGGGACATGGATGAGGACCCCAGCTGCCCGCAG
  CTCCCTCCCAGAGACTCTCCCAGGTGCCTCATGCTGGCCTTGTCACAAAGCGACCCAACT
  TTTGGCAAGAAGAGCTTTGAGCAGACCTTGACAGTGGAGCTCTGTGGCACAGCAGGACTC
  ACCCCACCCACCACACCACCGTACAAGCCCACAGAGGAGGATCCCTTCAAACCAGACATC
  AAGCATAGTCTAGGCAAAGAAATAGCTCTCAGCCTCCCCTCCCCTGAGGGCCTCTCACTC
  AAGGCCACCCCAGGGGCTGCCCACAAGCTGCCAAAGAAGCACCCAGAGCGAAGTGAGCTC
  CTGTCCCACCTGCGACATGCCACAGCCCAGCCAGCCTCCCAGGCTGGCCAGAAGCGTCCC
  TTCTCCTGTTCCTTTGGAGACCATGACTACTGCCAGGTGCTCCGACCAGAAGGCGTCCTG
  CAAAGGAAGGTGCTGAGGTCCTGGGAGCCGTCTGGGGTTCACCTTGAGGACTGGCCCCAG
  CAGGGTGCCCCTTGGGCTGAGGCACAGGCCCCTGGCAGGGAGGAAGACAGAAGCTGTGAT
  GCTGGCGCCCCACCCAAGGACAGCACGCTGCTGAGAGACCATGAGATCCGTGCCAGCCTC
  ACCAAACACTTTGGGCTGCTGGAGACCGCCCTGGAGGAGGAAGACCTGGCCTCCTGCAAG
  AGCCCTGAGTATGACACTGTCTTTGAAGACAGCAGCAGCAGCAGCGGCGAGAGCAGCTTC
  CTCCCAGAGGAGGAAGAGGAAGAAGGGGAGGAGGAGGAGGAGGACGATGAAGAAGAGGAC
  TCAGGGGTCAGCCCCACTTGCTCTGACCACTGCCCCTACCAGAGCCCACCAAGCAAGGCC
  AACCGGCAGCTCTGTTCCCGCAGCCGCTCAAGCTCTGGCTCTTCACCCTGCCACTCCTGG
  TCACCAGCCACTCGAAGGAACTTCAGATGTGAGAGCAGAGGGCCGTGTTCAGACAGAACG
  CCAAGCATCCGGCACGCCAGGAAGCGGCGGGAAAAGGCCATTGGGGAAGGCCGCGTGGTG
  TACATTCAAAATCTCTCCAGCGACATGAGCTCCCGAGAGCTGAAGAGGCGCTTTGAAGTG
  TTTGGTGAGATTGAGGAGTGCGAGGTGCTGACAAGAAATAGGAGAGGCGAGAAGTACGGC
  TTCATCACCTACCGGTGTTCTGAGCACGCGGCCCTCTCTTTGACAAAGGGCGCTGCCCTG
  AGGAAGCGCAACGAGCCCTCCTTCCAGCTGAGCTACGGAGGGCTCCGGCACTTCTGCTGG
  CCCAGATACACTGACTACGATTCCAATTCAGAAGAGGCCCTTCCTGCGTCAGGGAAAAGC
  AAGTATGAAGCCATGGATTTTGACAGCTTACTGAAAGAGGCCCAGCAGAGCCTGCATTGA
  
• Restriction Sites: Please inquire
• ACCN: NM_001172699
• ORF Size: 2880 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_001172699.1, NP_001166170.1
• RefSeq Size: 10556
• RefSeq ORF: 2880
• Locus ID: 133522
• Protein Families: Druggable Genome, Transcription Factors
• Gene Summary: The protein encoded by this gene stimulates the activity of several transcription factors and nuclear receptors, including estrogen receptor alpha, nuclear respiratory factor 1, and glucocorticoid receptor. The encoded protein may be involved in fat oxidation, non-oxidative glucose metabolism, and the regulation of energy expenditure. This protein is downregulated in prediabetic and type 2 diabetes mellitus patients. Certain allelic variations in this gene increase the risk of the development of obesity. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2010]
  Transcript Variant: This variant (3) represents use of an alternate promoter and 5' UTR, uses a distinct start codon, and lacks an alternate in-frame exon in the 5' coding region, compared to variant 1. The resulting isoform (3) has a shorter and distinct N-terminus and lacks an internal segment, compared to isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.