PGC1 beta (PPARGC1B) (NM_001172698) Human Untagged Clone

CAT#: SC329238

PPARGC1B (untagged)-Human peroxisome proliferator-activated receptor gamma coactivator 1 beta (PPARGC1B) transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: PPARGC1B
• Synonyms: ERRL1; PERC; PGC-1(beta); PGC1B
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_001172698, the custom clone sequence may differ by one or more nucleotides
  ATGGCGGGGAACGACTGCGGCGCGCTGCTGGACGAAGAGCTCTCCTCCTTCTTCCTCAAC
  TATCTCGCTGACACGCAGGGTGGAGGGTCCGGGGAGGAGCAACTCTATGCTGACTTTCCA
  GAACTTGACCTCTCCCAGCTGGATGCCAGCGACTTTGACTCGGCCACCTGCTTTGGGGAG
  CTGCAGTGGTGCCCAGAGAACTCAGAGACTGAACCCAACCAGTACAGCCCCGATGACTCC
  GAGCTCTTCCAGATTGACAGTGAGAATGAGGCCCTCCTGGCAGAGCTCACCAAGACCCTG
  GATGACATCCCTGAAGATGACGTGGGTCTGGCTGCCTTCCCAGCCCTGGATGGTGGAGAC
  GCTCTATCATGCACCTCAGCTTCGCCTGCCCCCTCATCTGCACCCCCCAGCCCTGCCCCG
  GAGAAGCCCTCGGCCCCAGCCCCTGAGGTGGACGAGCTCTCACTGGCGGACAGCACCCAA
  GACAAGAAGGCTCCCATGATGCAGTCTCAGAGCCGAAGTTGTACAGAACTACATAAGCAC
  CTCACCTCGGCACAGTGCTGCCTGCAGGATCGGGGTCTGCAGCCACCATGCCTCCAGAGT
  CCCCGGCTCCCTGCCAAGGAGGACAAGGAGCCGGGTGAGGACTGCCCGAGCCCCCAGCCA
  GCTCCAGCCTCTCCCCGGGACTCCCTAGCTCTGGGCAGGGCAGACCCCGGTGCCCCGGTT
  TCCCAGGAAGACATGCAGGCGATGGTGCAACTCATACGCTACATGCACACCTACTGCCTC
  CCCCAGAGGAAGCTGCCCCCACAGACCCCTGAGCCACTCCCCAAGGCCTGCAGCAACCCC
  TCCCAGCAGGTCAGATCCCGGCCCTGGTCCCGGCACCACTCCAAAGCCTCCTGGGCTGAG
  TTCTCCATTCTGAGGGAACTTCTGGCTCAAGACGTGCTCTGTGATGTCAGCAAACCCTAC
  CGTCTGGCCACGCCTGTTTATGCCTCCCTCACACCTCGGTCAAGGCCCAGGCCCCCCAAA
  GACAGTCAGGCCTCCCCTGGTCGCCCGTCCTCGGTGGAGGAGGTAAGGATCGCAGCTTCA
  CCCAAGAGCACCGGGCCCAGACCAAGCCTGCGCCCACTGCGGCTGGAGGTGAAAAGGGAG
  GTCCGCCGGCCTGCCAGACTGCAGCAGCAGGAGGAGGAAGACGAGGAAGAAGAGGAGGAG
  GAAGAGGAAGAAGAAAAAGAGGAGGAGGAGGAGTGGGGCAGGAAAAGGCCAGGCCGAGGC
  CTGCCATGGACGAAGCTGGGGAGGAAGCTGGAGAGCTCTGTGTGCCCCGTGCGGCGTTCT
  CGGAGACTGAACCCTGAGCTGGGCCCCTGGCTGACATTTGCAGATGAGCCGCTGGTCCCC
  TCGGAGCCCCAAGGTGCTCTGCCCTCACTGTGCCTGGCTCCCAAGGCCTACGACGTAGAG
  CGGGAGCTGGGCAGCCCCACGGACGAGGACAGTGGCCAAGACCAGCAGCTCCTACGGGGA
  CCCCAGATCCCTGCCCTGGAGAGCCCCTGTGAGAGTGGGTGTGGGGACATGGATGAGGAC
  CCCAGCTGCCCGCAGCTCCCTCCCAGAGACTCTCCCAGGTGCCTCATGCTGGCCTTGTCA
  CAAAGCGACCCAACTTTTGGCAAGAAGAGCTTTGAGCAGACCTTGACAGTGGAGCTCTGT
  GGCACAGCAGGACTCACCCCACCCACCACACCACCGTACAAGCCCACAGAGGAGGATCCC
  TTCAAACCAGACATCAAGCATAGTCTAGGCAAAGAAATAGCTCTCAGCCTCCCCTCCCCT
  GAGGGCCTCTCACTCAAGGCCACCCCAGGGGCTGCCCACAAGCTGCCAAAGAAGCACCCA
  GAGCGAAGTGAGCTCCTGTCCCACCTGCGACATGCCACAGCCCAGCCAGCCTCCCAGGCT
  GGCCAGAAGCGTCCCTTCTCCTGTTCCTTTGGAGACCATGACTACTGCCAGGTGCTCCGA
  CCAGAAGGCGTCCTGCAAAGGAAGGTGCTGAGGTCCTGGGAGCCGTCTGGGGTTCACCTT
  GAGGACTGGCCCCAGCAGGGTGCCCCTTGGGCTGAGGCACAGGCCCCTGGCAGGGAGGAA
  GACAGAAGCTGTGATGCTGGCGCCCCACCCAAGGACAGCACGCTGCTGAGAGACCATGAG
  ATCCGTGCCAGCCTCACCAAACACTTTGGGCTGCTGGAGACCGCCCTGGAGGAGGAAGAC
  CTGGCCTCCTGCAAGAGCCCTGAGTATGACACTGTCTTTGAAGACAGCAGCAGCAGCAGC
  GGCGAGAGCAGCTTCCTCCCAGAGGAGGAAGAGGAAGAAGGGGAGGAGGAGGAGGAGGAC
  GATGAAGAAGAGGACTCAGGGGTCAGCCCCACTTGCTCTGACCACTGCCCCTACCAGAGC
  CCACCAAGCAAGGCCAACCGGCAGCTCTGTTCCCGCAGCCGCTCAAGCTCTGGCTCTTCA
  CCCTGCCACTCCTGGTCACCAGCCACTCGAAGGAACTTCAGATGTGAGAGCAGAGGGCCG
  TGTTCAGACAGAACGCCAAGCATCCGGCACGCCAGGAAGCGGCGGGAAAAGGCCATTGGG
  GAAGGCCGCGTGGTGTACATTCAAAATCTCTCCAGCGACATGAGCTCCCGAGAGCTGAAG
  AGGCGCTTTGAAGTGTTTGGTGAGATTGAGGAGTGCGAGGTGCTGACAAGAAATAGGAGA
  GGCGAGAAGTACGGCTTCATCACCTACCGGTGTTCTGAGCACGCGGCCCTCTCTTTGACA
  AAGGGCGCTGCCCTGAGGAAGCGCAACGAGCCCTCCTTCCAGCTGAGCTACGGAGGGCTC
  CGGCACTTCTGCTGGCCCAGATACACTGACTACGATTCCAATTCAGAAGAGGCCCTTCCT
  GCGTCAGGGAAAAGCAAGTATGAAGCCATGGATTTTGACAGCTTACTGAAAGAGGCCCAG
  CAGAGCCTGCATTGA
  
• Restriction Sites: Please inquire
• ACCN: NM_001172698
• ORF Size: 2955 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_001172698.1, NP_001166169.1
• RefSeq Size: 10525
• RefSeq ORF: 2955
• Locus ID: 133522
• Protein Families: Druggable Genome, Transcription Factors
• Gene Summary: The protein encoded by this gene stimulates the activity of several transcription factors and nuclear receptors, including estrogen receptor alpha, nuclear respiratory factor 1, and glucocorticoid receptor. The encoded protein may be involved in fat oxidation, non-oxidative glucose metabolism, and the regulation of energy expenditure. This protein is downregulated in prediabetic and type 2 diabetes mellitus patients. Certain allelic variations in this gene increase the risk of the development of obesity. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2010]
  Transcript Variant: This variant (2) lacks an alternate in-frame exon in the 5' coding region, compared to variant 1. The resulting isoform (2) lacks an internal segment, compared to isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.