TJP2 (NM_001170630) Human Untagged Clone

CAT#: SC329243

TJP2 (untagged)-Human tight junction protein 2 (zona occludens 2) (TJP2) transcript variant 6

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: TJP2
• Synonyms: C9DUPq21.11; DFNA51; DUP9q21.11; PFIC4; X104; ZO2
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_001170630, the custom clone sequence may differ by one or more nucleotides
  ATGCCGGTGCGAGGAGACCGCGGGTTTCCACCCCGGCGGGAGCTGTCAGGTTGGCTCCGC
  GCCCCAGGCATGGAAGAGCTGATATGGGAACAGTACACTGTGACCCTACAAAAGGATTCC
  AAAAGAGGATTTGGAATTGCAGTGTCCGGAGGCAGAGACAACCCCCACTTTGAAAATGGA
  GAAACGTCAATTGTCATTTCTGATGTGCTCCCGGGTGGGCCTGCTGATGGGCTGCTCCAA
  GAAAATGACAGAGTGGTCATGGTCAATGGCACCCCCATGGAGGATGTGCTTCATTCGTTT
  GCAGTTCAGCAGCTCAGAAAAAGTGGGAAGGTCGCTGCTATTGTGGTCAAGAGGCCCCGG
  AAGGTCCAGGTGGCCGCACTTCAGGCCAGCCCTCCCCTGGATCAGGATGACCGGGCTTTT
  GAGGTGATGGACGAGTTTGATGGCAGAAGTTTCCGGAGTGGCTACAGCGAGAGGAGCCGG
  CTGAACAGCCATGGGGGGCGCAGCCGCAGCTGGGAGGACAGCCCGGAAAGGGGGCGTCCC
  CATGAGCGGGCCCGGAGCCGGGAGCGGGACCTCAGCCGGGACCGGAGCCGTGGCCGGAGC
  CTGGAGCGGGGCCTGGACCAAGACCATGCGCGCACCCGAGACCGCAGCCGTGGCCGGAGC
  CTGGAGCGGGGCCTGGACCACGACTTTGGGCCATCCCGGGACCGGGACCGTGACCGCAGC
  CGCGGCCGGAGCATTGACCAGGACTACGAGCGAGCCTATCACCGGGCCTACGACCCAGAC
  TACGAGCGGGCCTACAGCCCGGAGTACAGGCGCGGGGCCCGCCACGATGCCCGCTCTCGG
  GGACCCCGAAGCCGCAGCCGCGAGCACCCGCACTCACGGAGCCCCAGCCCCGAGCCTAGG
  GGGCGGCCGGGGCCCATCGGGGTCCTCCTGATGAAAAGCAGAGCGAACGAAGAGTATGGT
  CTCCGGCTTGGGAGTCAGATCTTCGTAAAGGAAATGACCCGAACGGGTCTGGCAACTAAA
  GATGGCAACCTTCACGAAGGAGACATAATTCTCAAGATCAATGGGACTGTAACTGAGAAC
  ATGTCTTTAACGGATGCTCGAAAATTGATAGAAAAGTCAAGAGGAAAACTACAGCTAGTG
  GTGTTGAGAGACAGCCAGCAGACCCTCATCAACATCCCGTCATTAAATGACAGTGACTCA
  GAAATAGAAGATATTTCAGAAATAGAGTCAAACCGATCATTTTCTCCAGAGGAGAGACGT
  CATCAGTATTCTGATTATGATTATCATTCCTCAAGTGAGAAGCTGAAGGAAAGGCCAAGT
  TCCAGAGAGGACACGCCGAGCAGATTGTCCAGGATGGGTGCGACACCCACTCCCTTTAAG
  TCCACAGGGGATATTGCAGGCACAGTTGTCCCAGAGACCAACAAGGAACCCAGATACCAA
  GAGGACCCCCCAGCTCCTCAACCAAAAGCAGCCCCGAGAACTTTTCTTCGTCCTAGTCCT
  GAAGATGAAGCAATATATGGCCCTAATACCAAAATGGTAAGGTTCAAGAAGGGAGACAGC
  GTGGGCCTCCGGTTGGCTGGTGGCAATGATGTCGGGATATTTGTTGCTGGCATTCAAGAA
  GGGACCTCGGCGGAGCAGGAGGGCCTTCAAGAAGGAGACCAGATTCTGAAGGTGAACACA
  CAGGATTTCAGAGGATTAGTGCGGGAGGATGCCGTTCTCTACCTGTTAGAAATCCCTAAA
  GGTGAAATGGTGACCATTTTAGCTCAGAGCCGAGCCGATGTGTATAGAGACATCCTGGCT
  TGTGGCAGAGGGGATTCGTTTTTTATAAGAAGCCACTTTGAATGTGAGAAGGAAACTCCA
  CAGAGCCTGGCCTTCACCAGAGGGGAGGTCTTCCGAGTGGTAGACACACTGTATGACGGC
  AAGCTGGGCAACTGGCTGGCTGTGAGGATTGGGAACGAGTTGGAGAAAGGCTTAATCCCC
  AACAAGAGCAGAGCTGAACAAATGGCCAGTGTTCAAAATGCCCAGAGAGACAACGCTGGG
  GACCGGGCAGATTTCTGGAGAATGCGTGGCCAGAGGTCTGGGGTGAAGAAGAACCTGAGG
  AAAAGTCGGGAAGACCTCACAGCTGTTGTGTCTGTCAGCACCAAGTTCCCAGCTTATGAG
  AGGGTTTTGCTGCGAGAAGCTGGTTTCAAGAGACCTGTGGTCTTATTCGGCCCCATAGCT
  GATATAGCAATGGAAAAATTGGCTAATGAGTTACCTGACTGGTTTCAAACTGCTAAAACG
  GAACCAAAAGATGCAGGATCTGAGAAATCCACTGGAGTGGTCCGGTTAAATACCGTGAGG
  CAAATTATTGAACAGGATAAGCATGCACTACTGGATGTGACTCCGAAAGCTGTGGACCTG
  TTGAATTACACCCAGTGGTTCCCAATTGTGATTTTTTTCAACCCAGACTCCAGACAAGGT
  GTCAAAACCATGAGACAAAGGTTAAATCCAACGTCCAACAAAAGTTCTCGAAAGTTATTT
  GATCAAGCCAACAAGCTTAAAAAAACGTGTGCACACCTTTTTACAGCTACAATCAACCTA
  AATTCAGCCAATGATAGCTGGTTTGGCAGCTTAAAGGACACTATTCAGCATCAGCAAGGA
  GAAGCGGTTTGGGTCTCTGAAGGAAAGATGGAAGGGATGGATGATGACCCCGAAGACCGC
  ATGTCCTACTTAACCGCCATGGGCGCGGACTATCTGAGTTGCGACAGCCGCCTCATCAGT
  GACTTTGAAGACACGGACGGTGAAGGAGGCGCCTACACTGACAATGAGCTGGATGAGCCA
  GCCGAGGAGCCGCTGGTGTCGTCCATCACCCGCTCCTCGGAGCCGGTGCAGCACGAGGAG
  GTGAGGCGAGGCAGGCCACGGGCAGGAACAGGAGAGCCTGGTGTTTTCCTTGCACTCTCG
  TGGACAGCTGTGTGTTCAGGGTGCTGTGGAAGGCATTCCTAA
  
• Restriction Sites: Please inquire
• ACCN: NM_001170630
• ORF Size: 2982 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_001170630.1, NP_001164101.1
• RefSeq Size: 4720
• RefSeq ORF: 2982
• Locus ID: 9414
• Protein Pathways: Tight junction, Vibrio cholerae infection
• Gene Summary: This gene encodes a zonula occluden that is a member of the membrane-associated guanylate kinase homolog family. The encoded protein functions as a component of the tight junction barrier in epithelial and endothelial cells and is necessary for proper assembly of tight junctions. Mutations in this gene have been identified in patients with hypercholanemia, and genomic duplication of a 270 kb region including this gene causes autosomal dominant deafness-51. Alternatively spliced transcripts encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Nov 2011]
  Transcript Variant: This variant (6) differs in the 3' UTR and coding region, compared to variant 1. The encoded isoform (6) is shorter and has a distinct C-terminus compared to isoform (1).