TJP2 (NM_001170415) Human Untagged Clone

CAT#: SC329302

TJP2 (untagged)-Human tight junction protein 2 (zona occludens 2) (TJP2) transcript variant 4

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: TJP2
• Synonyms: C9DUPq21.11; DFNA51; DUP9q21.11; PFIC4; X104; ZO2
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_001170415, the custom clone sequence may differ by one or more nucleotides
  ATGAAGACTGCTCAAGCCCTACATAGGATGTGGATCCAGGCTGTTAAAAAGTTGAGGAGA
  TGGAAAGGCCGTGCCCCAGGCATGGAAGAGCTGATATGGGAACAGTACACTGTGACCCTA
  CAAAAGGATTCCAAAAGAGGATTTGGAATTGCAGTGTCCGGAGGCAGAGACAACCCCCAC
  TTTGAAAATGGAGAAACGTCAATTGTCATTTCTGATGTGCTCCCGGGTGGGCCTGCTGAT
  GGGCTGCTCCAAGAAAATGACAGAGTGGTCATGGTCAATGGCACCCCCATGGAGGATGTG
  CTTCATTCGTTTGCAGTTCAGCAGCTCAGAAAAAGTGGGAAGGTCGCTGCTATTGTGGTC
  AAGAGGCCCCGGAAGGTCCAGGTGGCCGCACTTCAGGCCAGCCCTCCCCTGGATCAGGAT
  GACCGGGCTTTTGAGGTGATGGACGAGTTTGATGGCAGAAGTTTCCGGAGTGGCTACAGC
  GAGAGGAGCCGGCTGAACAGCCATGGGGGGCGCAGCCGCAGCTGGGAGGACAGCCCGGAA
  AGGGGGCGTCCCCATGAGCGGGCCCGGAGCCGGGAGCGGGACCTCAGCCGGGACCGGAGC
  CGTGGCCGGAGCCTGGAGCGGGGCCTGGACCAAGACCATGCGCGCACCCGAGACCGCAGC
  CGTGGCCGGAGCCTGGAGCGGGGCCTGGACCACGACTTTGGGCCATCCCGGGACCGGGAC
  CGTGACCGCAGCCGCGGCCGGAGCATTGACCAGGACTACGAGCGAGCCTATCACCGGGCC
  TACGACCCAGACTACGAGCGGGCCTACAGCCCGGAGTACAGGCGCGGGGCCCGCCACGAT
  GCCCGCTCTCGGGGACCCCGAAGCCGCAGCCGCGAGCACCCGCACTCACGGAGCCCCAGC
  CCCGAGCCTAGGGGGCGGCCGGGGCCCATCGGGGTCCTCCTGATGAAAAGCAGAGCGAAC
  GAAGAGTATGGTCTCCGGCTTGGGAGTCAGATCTTCGTAAAGGAAATGACCCGAACGGGT
  CTGGCAACTAAAGATGGCAACCTTCACGAAGGAGACATAATTCTCAAGATCAATGGGACT
  GTAACTGAGAACATGTCTTTAACGGATGCTCGAAAATTGATAGAAAAGTCAAGAGGAAAA
  CTACAGCTAGTGGTGTTGAGAGACAGCCAGCAGACCCTCATCAACATCCCGTCATTAAAT
  GACAGTGACTCAGAAATAGAAGATATTTCAGAAATAGAGTCAAACCGATCATTTTCTCCA
  GAGGAGAGACGTCATCAGTATTCTGATTATGATTATCATTCCTCAAGTGAGAAGCTGAAG
  GAAAGGCCAAGTTCCAGAGAGGACACGCCGAGCAGATTGTCCAGGATGGGTGCGACACCC
  ACTCCCTTTAAGTCCACAGGGGATATTGCAGGCACAGTTGTCCCAGAGACCAACAAGGAA
  CCCAGATACCAAGAGGACCCCCCAGCTCCTCAACCAAAAGCAGCCCCGAGAACTTTTCTT
  CGTCCTAGTCCTGAAGATGAAGCAATATATGGCCCTAATACCAAAATGGTAAGGTTCAAG
  AAGGGAGACAGCGTGGGCCTCCGGTTGGCTGGTGGCAATGATGTCGGGATATTTGTTGCT
  GGCATTCAAGAAGGGACCTCGGCGGAGCAGGAGGGCCTTCAAGAAGGAGACCAGATTCTG
  AAGGTGAACACACAGGATTTCAGAGGATTAGTGCGGGAGGATGCCGTTCTCTACCTGTTA
  GAAATCCCTAAAGGTGAAATGGTGACCATTTTAGCTCAGAGCCGAGCCGATGTGTATAGA
  GACATCCTGGCTTGTGGCAGAGGGGATTCGTTTTTTATAAGAAGCCACTTTGAATGTGAG
  AAGGAAACTCCACAGAGCCTGGCCTTCACCAGAGGGGAGGTCTTCCGAGTGGTAGACACA
  CTGTATGACGGCAAGCTGGGCAACTGGCTGGCTGTGAGGATTGGGAACGAGTTGGAGAAA
  GGCTTAATCCCCAACAAGAGCAGAGCTGAACAAATGGCCAGTGTTCAAAATGCCCAGAGA
  GACAACGCTGGGGACCGGGCAGATTTCTGGAGAATGCGTGGCCAGAGGTCTGGGGTGAAG
  AAGAACCTGAGGAAAAGTCGGGAAGACCTCACAGCTGTTGTGTCTGTCAGCACCAAGTTC
  CCAGCTTATGAGAGGGTTTTGCTGCGAGAAGCTGGTTTCAAGAGACCTGTGGTCTTATTC
  GGCCCCATAGCTGATATAGCAATGGAAAAATTGGCTAATGAGTTACCTGACTGGTTTCAA
  ACTGCTAAAACGGAACCAAAAGATGCAGGATCTGAGAAATCCACTGGAGTGGTCCGGTTA
  AATACCGTGAGGCAAATTATTGAACAGGATAAGCATGCACTACTGGATGTGACTCCGAAA
  GCTGTGGACCTGTTGAATTACACCCAGTGGTTCCCAATTGTGATTTTTTTCAACCCAGAC
  TCCAGACAAGGTGTCAAAACCATGAGACAAAGGTTAAATCCAACGTCCAACAAAAGTTCT
  CGAAAGTTATTTGATCAAGCCAACAAGCTTAAAAAAACGTGTGCACACCTTTTTACAGCT
  ACAATCAACCTAAATTCAGCCAATGATAGCTGGTTTGGCAGCTTAAAGGACACTATTCAG
  CATCAGCAAGGAGAAGCGGTTTGGGTCTCTGAAGGAAAGATGGAAGGGATGGATGATGAC
  CCCGAAGACCGCATGTCCTACTTAACCGCCATGGGCGCGGACTATCTGAGTTGCGACAGC
  CGCCTCATCAGTGACTTTGAAGACACGGACGGTGAAGGAGGCGCCTACACTGACAATGAG
  CTGGATGAGCCAGCCGAGGAGCCGCTGGTGTCGTCCATCACCCGCTCCTCGGAGCCGGTG
  CAGCACGAGGAGGCCAAAACCCAGAACAAAGAAGAATCCTATGACTTCTCCAAATCCTAT
  GAATATAAGTCAAACCCCTCTGCCGTTGCTGGTAATGAAACTCCTGGGGCATCTACCAAA
  GGTTATCCTCCTCCTGTTGCAGCAAAACCTACCTTTGGGCGGTCTATACTGAAGCCCTCC
  ACTCCCATCCCTCCTCAAGAGGGTGAGGAGGTGGGAGAGAGCAGTGAGGAGCAAGATAAT
  GCTCCCAAATCAGTCCTGGGCAAAGTCAAAATATTTGAGAAGATGGATCACAAGGCCAGG
  TTACAGAGAATGCAGGAGCTCCAGGAAGCACAGAATGCAAGGATCGAAATTGCCCAGAAG
  CATCCTGATATCTATGCAGTTCCAATCAAAACGCACAAGCCAGACCCTGGCACGCCCCAG
  CACACGAGTTCCAGACCCCCTGAGCCACAGAAAGCTCCTTCCAGACCTTATCAGGATACC
  AGAGGAAGTTATGGCAGTGATGCCGAGGAGGAGGAGTACCGCCAGCAGCTGTCAGAACAC
  TCCAAGCGCGGTTACTATGGCCAGTCTGCCCGATACCGGGACACAGAATTATAG
  
• Restriction Sites: Please inquire
• ACCN: NM_001170415
• ORF Size: 3474 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_001170415.1, NP_001163886.1
• RefSeq Size: 4459
• RefSeq ORF: 3474
• Locus ID: 9414
• Protein Pathways: Tight junction, Vibrio cholerae infection
• Gene Summary: This gene encodes a zonula occluden that is a member of the membrane-associated guanylate kinase homolog family. The encoded protein functions as a component of the tight junction barrier in epithelial and endothelial cells and is necessary for proper assembly of tight junctions. Mutations in this gene have been identified in patients with hypercholanemia, and genomic duplication of a 270 kb region including this gene causes autosomal dominant deafness-51. Alternatively spliced transcripts encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Nov 2011]
  Transcript Variant: This variant (4) has multiple differences, compared to variant 1. These differences include a distinct 5' UTR and translation initiation at a downstream start codon, compared to variant 1. The encoded isoform (4) is shorter and has a distinct N-terminus compared to isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.