TJP2 (NM_001170416) Human Untagged Clone

CAT#: SC329315

TJP2 (untagged)-Human tight junction protein 2 (zona occludens 2) (TJP2) transcript variant 3

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: TJP2
• Synonyms: C9DUPq21.11; DFNA51; DUP9q21.11; PFIC4; X104; ZO2
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_001170416, the custom clone sequence may differ by one or more nucleotides
  ATGAAGACTGCTCAAGCCCTACATAGGATGTGGATCCAGGCTGTTAAAAAGTTGAGGAGA
  TGGAAAGGCCGTGTGAGTCCCTCTGCAAGCTCTCCCCTTGTTTTCCCCAACCTTTCTTCA
  TGGGAAGGGGAGGGAAGCAAAACCATTCTCACAGCCCCAGGCATGGAAGAGCTGATATGG
  GAACAGTACACTGTGACCCTACAAAAGGATTCCAAAAGAGGATTTGGAATTGCAGTGTCC
  GGAGGCAGAGACAACCCCCACTTTGAAAATGGAGAAACGTCAATTGTCATTTCTGATGTG
  CTCCCGGGTGGGCCTGCTGATGGGCTGCTCCAAGAAAATGACAGAGTGGTCATGGTCAAT
  GGCACCCCCATGGAGGATGTGCTTCATTCGTTTGCAGTTCAGCAGCTCAGAAAAAGTGGG
  AAGGTCGCTGCTATTGTGGTCAAGAGGCCCCGGAAGGTCCAGGTGGCCGCACTTCAGGCC
  AGCCCTCCCCTGGATCAGGATGACCGGGCTTTTGAGGTGATGGACGAGTTTGATGGCAGA
  AGTTTCCGGAGTGGCTACAGCGAGAGGAGCCGGCTGAACAGCCATGGGGGGCGCAGCCGC
  AGCTGGGAGGACAGCCCGGAAAGGGGGCGTCCCCATGAGCGGGCCCGGAGCCGGGAGCGG
  GACCTCAGCCGGGACCGGAGCCGTGGCCGGAGCCTGGAGCGGGGCCTGGACCAAGACCAT
  GCGCGCACCCGAGACCGCAGCCGTGGCCGGAGCCTGGAGCGGGGCCTGGACCACGACTTT
  GGGCCATCCCGGGACCGGGACCGTGACCGCAGCCGCGGCCGGAGCATTGACCAGGACTAC
  GAGCGAGCCTATCACCGGGCCTACGACCCAGACTACGAGCGGGCCTACAGCCCGGAGTAC
  AGGCGCGGGGCCCGCCACGATGCCCGCTCTCGGGGACCCCGAAGCCGCAGCCGCGAGCAC
  CCGCACTCACGGAGCCCCAGCCCCGAGCCTAGGGGGCGGCCGGGGCCCATCGGGGTCCTC
  CTGATGAAAAGCAGAGCGAACGAAGAGTATGGTCTCCGGCTTGGGAGTCAGATCTTCGTA
  AAGGAAATGACCCGAACGGGTCTGGCAACTAAAGATGGCAACCTTCACGAAGGAGACATA
  ATTCTCAAGATCAATGGGACTGTAACTGAGAACATGTCTTTAACGGATGCTCGAAAATTG
  ATAGAAAAGTCAAGAGGAAAACTACAGCTAGTGGTGTTGAGAGACAGCCAGCAGACCCTC
  ATCAACATCCCGTCATTAAATGACAGTGACTCAGAAATAGAAGATATTTCAGAAATAGAG
  TCAAACCGATCATTTTCTCCAGAGGAGAGACGTCATCAGTATTCTGATTATGATTATCAT
  TCCTCAAGTGAGAAGCTGAAGGAAAGGCCAAGTTCCAGAGAGGACACGCCGAGCAGATTG
  TCCAGGATGGGTGCGACACCCACTCCCTTTAAGTCCACAGGGGATATTGCAGGCACAGTT
  GTCCCAGAGACCAACAAGGAACCCAGATACCAAGAGGACCCCCCAGCTCCTCAACCAAAA
  GCAGCCCCGAGAACTTTTCTTCGTCCTAGTCCTGAAGATGAAGCAATATATGGCCCTAAT
  ACCAAAATGGTAAGGTTCAAGAAGGGAGACAGCGTGGGCCTCCGGTTGGCTGGTGGCAAT
  GATGTCGGGATATTTGTTGCTGGCATTCAAGAAGGGACCTCGGCGGAGCAGGAGGGCCTT
  CAAGAAGGAGACCAGATTCTGAAGGTGAACACACAGGATTTCAGAGGATTAGTGCGGGAG
  GATGCCGTTCTCTACCTGTTAGAAATCCCTAAAGGTGAAATGGTGACCATTTTAGCTCAG
  AGCCGAGCCGATGTGTATAGAGACATCCTGGCTTGTGGCAGAGGGGATTCGTTTTTTATA
  AGAAGCCACTTTGAATGTGAGAAGGAAACTCCACAGAGCCTGGCCTTCACCAGAGGGGAG
  GTCTTCCGAGTGGTAGACACACTGTATGACGGCAAGCTGGGCAACTGGCTGGCTGTGAGG
  ATTGGGAACGAGTTGGAGAAAGGCTTAATCCCCAACAAGAGCAGAGCTGAACAAATGGCC
  AGTGTTCAAAATGCCCAGAGAGACAACGCTGGGGACCGGGCAGATTTCTGGAGAATGCGT
  GGCCAGAGGTCTGGGGTGAAGAAGAACCTGAGGAAAAGTCGGGAAGACCTCACAGCTGTT
  GTGTCTGTCAGCACCAAGTTCCCAGCTTATGAGAGGGTTTTGCTGCGAGAAGCTGGTTTC
  AAGAGACCTGTGGTCTTATTCGGCCCCATAGCTGATATAGCAATGGAAAAATTGGCTAAT
  GAGTTACCTGACTGGTTTCAAACTGCTAAAACGGAACCAAAAGATGCAGGATCTGAGAAA
  TCCACTGGAGTGGTCCGGTTAAATACCGTGAGGCAAATTATTGAACAGGATAAGCATGCA
  CTACTGGATGTGACTCCGAAAGCTGTGGACCTGTTGAATTACACCCAGTGGTTCCCAATT
  GTGATTTTTTTCAACCCAGACTCCAGACAAGGTGTCAAAACCATGAGACAAAGGTTAAAT
  CCAACGTCCAACAAAAGTTCTCGAAAGTTATTTGATCAAGCCAACAAGCTTAAAAAAACG
  TGTGCACACCTTTTTACAGCTACAATCAACCTAAATTCAGCCAATGATAGCTGGTTTGGC
  AGCTTAAAGGACACTATTCAGCATCAGCAAGGAGAAGCGGTTTGGGTCTCTGAAGGAAAG
  ATGGAAGGGATGGATGATGACCCCGAAGACCGCATGTCCTACTTAACCGCCATGGGCGCG
  GACTATCTGAGTTGCGACAGCCGCCTCATCAGTGACTTTGAAGACACGGACGGTGAAGGA
  GGCGCCTACACTGACAATGAGCTGGATGAGCCAGCCGAGGAGCCGCTGGTGTCGTCCATC
  ACCCGCTCCTCGGAGCCGGTGCAGCACGAGGAGAGCATAAGGAAACCCAGCCCAGAGCCA
  CGAGCTCAGATGAGGAGGGCTGCTAGCAGCGATCAACTTAGGGACAATAGCCCGCCCCCA
  GCATTCAAGCCAGAGCCGCCCAAGGCCAAAACCCAGAACAAAGAAGAATCCTATGACTTC
  TCCAAATCCTATGAATATAAGTCAAACCCCTCTGCCGTTGCTGGTAATGAAACTCCTGGG
  GCATCTACCAAAGGTTATCCTCCTCCTGTTGCAGCAAAACCTACCTTTGGGCGGTCTATA
  CTGAAGCCCTCCACTCCCATCCCTCCTCAAGAGGGTGAGGAGGTGGGAGAGAGCAGTGAG
  GAGCAAGATAATGCTCCCAAATCAGTCCTGGGCAAAGTCAAAATATTTGAGAAGATGGAT
  CACAAGGCCAGGTTACAGAGAATGCAGGAGCTCCAGGAAGCACAGAATGCAAGGATCGAA
  ATTGCCCAGAAGCATCCTGATATCTATGCAGTTCCAATCAAAACGCACAAGCCAGACCCT
  GGCACGCCCCAGCACACGAGTTCCAGACCCCCTGAGCCACAGAAAGCTCCTTCCAGACCT
  TATCAGGATACCAGAGGAAGTTATGGCAGTGATGCCGAGGAGGAGGAGTACCGCCAGCAG
  CTGTCAGAACACTCCAAGCGCGGTTACTATGGCCAGTCTGCCCGATACCGGGACACAGAA
  TTATAG
  
• Restriction Sites: Please inquire
• ACCN: NM_001170416
• ORF Size: 3666 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_001170416.1, NP_001163887.1
• RefSeq Size: 4500
• RefSeq ORF: 3666
• Locus ID: 9414
• Protein Pathways: Tight junction, Vibrio cholerae infection
• Gene Summary: This gene encodes a zonula occluden that is a member of the membrane-associated guanylate kinase homolog family. The encoded protein functions as a component of the tight junction barrier in epithelial and endothelial cells and is necessary for proper assembly of tight junctions. Mutations in this gene have been identified in patients with hypercholanemia, and genomic duplication of a 270 kb region including this gene causes autosomal dominant deafness-51. Alternatively spliced transcripts encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Nov 2011]
  Transcript Variant: This variant (3) differs in the 5' UTR and 5' coding region, and initiates translation at an alternate start codon, compared to variant 1. The encoded isoform (3) has a distinct N-terminus and is longer than isoform 1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments.