TANK (NM_001199135) Human Untagged Clone

CAT#: SC329485

TANK (untagged) - Homo sapiens TRAF family member-associated NFKB activator (TANK), transcript variant 3

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: TANK
• Synonyms: I-TRAF; ITRAF; TRAF2
• Vector: pCMV6 series
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_001199135, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGGATAAAAACATTGGCGAGCAACTCAATAAAGCGTATGAAGCCTTCCGGCAGGCATGCATGGATAGAG
  ATTCTGCAGTAAAAGAATTACAGCAAAAGACTGAGAACTATGAGCAGAGAATACGTGAACAACAGGAACA
  GCTGTCACTTCAACAGACTATTATTGACAAGCTAAAATCTCAGTTACTTCTTGTGAATTCCACTCAAGAT
  AACAATTATGGCTGTGTTCCTCTGCTTGAAGACAGTGAAACAAGAAAGAATAATTTGACTCTTGATCAGC
  CACAAGATAAAGTGATTTCAGGAATAGCAAGAGAAAAACTACCAAAGGTAAGAAGACAAGAGGTTTCTTC
  TCCTAGAAAAGAAACTTCAGCAAGGAGTCTTGGCAGTCCTTTGCTCCATGAAAGGGGTAATATAGAGAAG
  ACTTTCTGGGATCTGAAAGAAGAATTTCATAAAATATGCATGCTAGCAAAAGCACAGAAAGACCACTTAA
  GCAAACTTAATATACCAGACACTGCAACTGAAACACAGTGCTCTGTGCCTATACAGTGTACGGATAAAAC
  AGATAAACAAGAAGCGCTGTTTAAGCCTCAGGCTAAAGATGATATAAATAGAGGTGCACCATCCATCACA
  TCTGTCACACCAAGAGGACTGTGCAGAGATGAGGAAGACACCTCTTTTGAATCACTTTCTAAATTCAATG
  TCAAGTTTCCACCTATGGACAATGACTCAACTTTCTTACATAGCACTCCAGAGAGACCCGGCATCCTTAG
  TCCTGCCACGTCTGAGGCAGTGTGCCAAGAGAAATTTAATATGGAGTTCAGAGACAACCCAGGGAACTTT
  GTTAAAACAGAAGAAACTTTATTTGAAATTCAGGGAATTGACCCCATAGCTTCAGCTATACAAAACCTTA
  AAACAACTGACAAAACAAAGCCCTCAAATCTCGTAAACACTTGTATCAGGACAACTCTGGATAGAGCTGC
  GTGTTTGCCACCTGGAGACCATAATGCATTATATGTAAATAGCTTCCCACTTCTGGACCCATCTGATGCA
  CCTTTTCCCTCACTCGATTCCCCGGGAAAAGCAATCCGAGGACCACAGCAGCCCATTTGGAAGCCCTTTC
  CTAATCAAGACAGTGACTCGGTGGTACTAAGTGGCACAGACTCAGAACTGCATATACCTCGAGTATGTGA
  ATTCTGTCAAGCAGTTTTCCCACCATCCATTACATCCAGGGGGGATTTCCTTCGGCATCTTAATTCACAC
  TTCAATGGAGAGACTTAA
  
  
• Restriction Sites: SgfI-MluI
• ACCN: NM_001199135
• ORF Size: 1278 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_001199135.1, NP_001186064.1
• RefSeq Size: 2060
• RefSeq ORF: 1278
• Locus ID: 10010
• Protein Families: Druggable Genome
• Protein Pathways: RIG-I-like receptor signaling pathway
• Gene Summary: The TRAF (tumor necrosis factor receptor-associated factor) family of proteins associate with and transduce signals from members of the tumor necrosis factor receptor superfamily. The protein encoded by this gene is found in the cytoplasm and can bind to TRAF1, TRAF2, or TRAF3, thereby inhibiting TRAF function by sequestering the TRAFs in a latent state in the cytoplasm. For example, the protein encoded by this gene can block TRAF2 binding to LMP1, the Epstein-Barr virus transforming protein, and inhibit LMP1-mediated NF-kappa-B activation. Three alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2010]
  Transcript Variant: This variant (3) has an alternate 5' UTR exon compared to variant 1. Variants 1 and 2 encode the same isoform (a).