DEPDC5 (NM_001242897) Human Untagged Clone

CAT#: SC330054

DEPDC5 (untagged) - Homo sapiens DEP domain containing 5 (DEPDC5), transcript variant 5

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: DEPDC5
• Synonyms: DEP.5; FFEVF; FFEVF1
• Vector: pCMV6 series
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_001242897, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGAGAACAACAAAGGTCTACAAACTCGTCATCCACAAGAAGGGCTTTGGGGGCAGTGATGATGAGCTAG
  TTGTGAACCCCAAAGTGTTCCCTCACATCAAGCTTGGAGACATTGTAGAGATTGCACACCCCAACGATGA
  ATACAGCCCTCTGCTTTTGCAGGTCAAGTCTCTTAAGGAAGATTTACAGAAGGAAACTATCAGTGTGGAC
  CAGACTGTGACTCAAGTGTTCCGGCTGAGACCTTATCAGGATGTCTATGTTAATGTCGTAGACCCTAAGG
  ATGTGACCCTTGACCTAGTGGAATTAACTTTTAAGGATCAGTATATTGGCCGTGGGGATATGTGGCGACT
  AAAGAAAAGTTTGGTCAGCACATGTGCCTATATCACCCAGAAGGTGGAGTTTGCTGGCATCAGAGCACAG
  GCTGGTGAACTGTGGGTTAAGAATGAGAAGGTCATGTGTGGCTACATCAGTGAAGATACCAGGGTGGTGT
  TTCGTTCTACGTCGGCTATGGTTTACATATTTATTCAGATGAGCTGTGAAATGTGGGATTTTGATATTTA
  TGGGGATTTGTATTTTGAGAAAGCTGTGAATGGTTTCCTTGCTGATCTATTTACCAAGTGGAAGGAGAAG
  AACTGTAGTCATGAAGTGACAGTGGTCCTGTTTTCTAGAACTTTCTATGATGCAAAATCTGTTGATGAAT
  TTCCTGAAATAAACCGAGCCTCAATTCGACAGGATCACAAGGGGAGATTCTATGAAGACTTTTACAAAGT
  GGTGGTGCAGAATGAGAGAAGAGAAGAATGGACTTCACTTCTCGTAACCATTAAAAAACTCTTCATCCAG
  TATCCAGTGTTGGTGCGACTGGAACAGGCAGAGGGCTTTCCTCAAGGAGATAATTCTACCTCAGCACAAG
  GAAACTACCTGGAGGCCATCAATCTGTCATTCAATGTGTTTGATAAGCACTACATCAACCGCAACTTTGA
  CCGAACTGGGCAGATGTCAGTGGTGATCACGCCCGGGGTGGGTGTCTTTGAAGTGGACCGCCTACTCATG
  ATCCTGACCAAGCAGCGGATGATAGATAATGGAATTGGTGTGGATTTGGTGTGCATGGGAGAGCAACCGT
  TACATGCTGTCCCATTGTTCAAGCTCCATAATCGGAGTGCTCCCCGTGATTCTCGTCTGGGCGATGACTA
  TAATATCCCTCACTGGATAAACCACAGTTTCTACACATCCAAAAGCCAGCTCTTTTGTAATAGTTTCACC
  CCACGAATAAAACTGGCAGGAAAGAAGCCCGCCTCTGAGAAAGCAAAAAATGGCCGTGATACATCTCTCG
  GGAGTCCAAAAGAATCTGAGAACGCCCTTCCCATCCAAGTAGATTATGACGCCTATGACGCTCAAGTGTT
  CAGGCTGCCCGGCCCATCCCGGGCCCAGTGCCTCACCACCTGCAGATCTGTGCGAGAGCGAGAGAGTCAC
  AGTCGAAAGAGTGCCAGCTCCTGTGATGTTTCATCCAGCCCTTCCCTACCAAGCCGCACACTGCCCACTG
  AGGAAGTGAGGAGCCAGGCTTCTGACGACAGCTCCCTAGGCAAGAGTGCCAACATCCTGATGATCCCACA
  CCCCCACCTGCACCAGTATGAAGTCAGCAGCTCCTTGGGATACACCAGCACTCGAGATGTCCTGGAGAAC
  ATGATGGAGCCACCACAGCGAGACTCCAGTGCACCAGGGAGGTTTCACGTTGGCAGTGCAGAATCCATGC
  TGCATGTTCGACCTGGTGGATACACGCCCCAGAGAGCACTGATTAACCCCTTCGCTCCCTCTCGGATGCC
  CATGAAGCTTACGTCCAACAGAAGGCGCTGGATGCACACTTTTCCTGTGGGTATGAATCCTAGGACCCAG
  AATAAGGATTCTCTAGAGGACAGTGTTTCTACCTCTCCAGACCCAATTCTGACACTGTCTGCTCCCCCTG
  TAGTGCCAGGCTTCTGTTGCACAGTTGGAGTGGACTGGAAGTCTCTCACTACTCCGGCGTGCCTCCCCCT
  TACCACCGACTACTTCCCTGACCGCCAGGGCCTGCAGAATGACTACACAGAGGGCTGTTATGATCTCCTT
  CCAGAAGCAGACATCGACAGGAGGGACGAAGATGGTGTGCAGATGACAGCCCAGCAGGTATTTGAAGAGT
  TTATTTGCCAACGTCTCATGCAGGGCTACCAAATCATAGTGCAGCCCAAGACACAGAAACCCAATCCTGC
  TGTCCCGCCCCCGCTGAGCAGTAGCCCACTCTATAGCCGAGGCCTTGTGTCCCGAAACCGCCCTGAGGAG
  GAGGACCAGTATTGGCTGAGTATGGGCAGAACGTTCCACAAAGTGACGCTGAAGGATAAGATGATCACAG
  TGACGCGATACCTTCCCAAGTATCCTTATGAATCTGCCCAGATCCACTACACCTACAGCCTCTGTCCTTC
  CCACTCAGACTCAGAGTTCGTCTCCTGCTGGGTGGAATTCTCCCACGAACGGCTGGAGGAGTACAAGTGG
  AATTACTTAGATCAGTATATCTGTTCTGCCGGCTCTGAAGACTTCAGCTTAATTGAGTCCCTGAAGTTCT
  GGAGGACCCGCTTCCTGCTGCTGCCAGCCTGTGTCACCGCCACCAAGCGCATCACGGAGGGGGAGGCCCA
  CTGCGACATCTATGGGGACAGGCCCCGTGCAGACGAGGACGAGTGGCAACTCCTGGATGGTTTTGTCCGC
  TTTGTGGAGGGCTTGAATCGCATTCGCAGGCGGCATCGCTCGGATCGCATGATGCGGAAAGGGACCGCCA
  TGAAAGGCTTGCAGATGACTGGGCCCATTTCCACGCATTCTCTGGAGTCAACTGCACCCCCAGTGGGGAA
  GAAGGGAACCTCAGCTCTCTCTGCCCTGTTGGAGATGGAGGCCAGTCAGAAGTGCCTGGGAGAACAGCAG
  GCAGCTGTGCATGGTGGGAAGAGCTCCGCCCAGTCAGCCGAGAGCAGCAGCGTTGCCATGACTCCCACCT
  ACATGGACAGCCCACGAAAGGTATCTGTGGACCAAACAGCCACTCCTATGTTGGACGGCACCAGTTTGGG
  CATATGCACAGGCCAATCCATGGACAGAGGCAACAGCCAGACCTTTGGGAACTCCCAGAACATAGGAGAA
  CAGGGCTACTCCTCCACAAACTCCAGTGACAGCAGCTCTCAGCAGCTGGTGGCAAGCTCCTTGACCTCAT
  CCTCTACCCTGACAGAGATCCTGGAAGCCATGAAGCACCCCTCGACAGGAGTCCAGCTGCTCTCTGAACA
  GAAGGGCCTCTCACCGTACTGCTTCATCAGCGCGGAGGTGGTACACTGGTTGGTGAACCACGTGGAGGGG
  ATCCAGACACAGGCGATGGCCATTGACATCATGCAGAAAATGCTGGAAGAGCAGCTCATCACACATGCAT
  CTGGCGAAGCCTGGCGGACCTTCATCTACGGCTTCTATTTCTACAAGATAGTAACGGACAAAGAGCCCGA
  CCGAGTGGCCATGCAGCAGCCCGCCACCACCTGGCACACAGCAGGAGTGGACGACTTCGCCAGCTTCCAG
  CGCAAGTGGTTTGAGGTGGCCTTTGTGGCAGAAGAGCTCGTGCACTCTGAGATTCCTGCCTTTCTCCTGC
  CCTGGCTGCCTAGCCGGCCAGCCTCCTATGCAAGTAGGCACAGCTCCTTTAGCCGAAGTTTTGGAGGACG
  GAGCCAGGCGGCAGCACTTTTAGCTGCCACTGTCCCAGAGCAGAGGACTGTGACCCTGGATGTTGACGTG
  AACAACCGCACAGACCGGCTGGAGTGGTGCAGCTGTTATTACCATGGCAACTTTTCTCTGAATGCAGCCT
  TTGAGATCAAGCTGCACTGGATGGCGGTGACCGCAGCAGTACTCTTCGAGATGGTCCAAGGTTGGCATCG
  GAAAGCCACCTCCTGTGGCTTCTTGTTAGTCCCAGTTTTGGAGGGGCCTTTTGCACTGCCCAGTTACCTG
  TATGGCGACCCCCTTCGTGCCCAGCTCTTCATCCCACTCAACATCAGCTGCTTGCTCAAGGAGGGCAGCG
  AGCACCTGTTTGATAGCTTTGAACCCGAAACGTACTGGGATCGAATGCACCTCTTCCAGGAAGCCATTGC
  ACACAGGTTTGGGTTTGTACAAGATAAATATTCTGCCTCTGCTTTTAACTTCCCTGCTGAGAACAAGCCT
  CAGTATATCCACGTTACAGGAACAGTGTTTCTGCAGCTGCCCTACTCCAAGCGCAAGTTCTCAGGGCAGC
  AGCGGCGGCGGCGGAACTCCACCAGCTCCACCAACCAGAACATGTTCTGCGAGGAGCGGGTCGGCTACAA
  CTGGGCCTACAACACCATGCTCACCAAAACATGGCGCTCCAGCGCCACAGGGGATGAAAAGTTTGCTGAT
  CGGCTGCTGAAGGACTTCACGGACTTCTGCATCAACCGTGACAACCGGCTGGTCACGTTCTGGACAAGTT
  GCCTGGAGAAGATGCATGCCAGTGCCCCGTGA
  
  
• Restriction Sites: SgfI-MluI
• ACCN: NM_001242897
• ORF Size: 4512 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_001242897.1, NP_001229826.1
• RefSeq Size: 5155
• RefSeq ORF: 4512
• Locus ID: 9681
• Gene Summary: This gene encodes a member of the IML1 family of proteins involved in G-protein signaling pathways. The mechanistic target of rapamycin complex 1 (mTORC1) pathway regulates cell growth by sensing the availability of nutrients. The protein encoded by this gene is a component of the GATOR1 (GAP activity toward Rags) complex which inhibits the amino acid-sensing branch of the mTORC1 pathway. Mutations in this gene are associated with autosomal dominant familial focal epilepsy with variable foci. A single nucleotide polymorphism in an intron of this gene has been associated with an increased risk of hepatocellular carcinoma in individuals with chronic hepatitis C virus infection. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2014]
  Transcript Variant: This variant (5) differs in the 5' UTR and lacks three in-frame exons in the coding region compared to variant 4. The encoded protein (isoform 5) is shorter than isoform 4.