STK36 (NM_001243313) Human Untagged Clone
CAT#: SC330114
STK36 (untagged) - Homo sapiens serine/threonine kinase 36 (STK36), transcript variant 2
"NM_001243313" in other vectors (2)
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Specifications
Product Data | |
Type | Human Untagged Clone |
Tag | Tag Free |
Symbol | STK36 |
Synonyms | FU |
Vector | pCMV6 series |
Sequence Data |
>NCBI ORF sequence for NM_001243313, the custom clone sequence may differ by one or more nucleotides
ATGGAAAAGTACCACGTGTTGGAGATGATTGGAGAAGGCTCTTTTGGGAGGGTGTACAAGGGTCGAAGAA AATACAGTGCTCAGGTCGTGGCCCTGAAGTTCATCCCAAAATTGGGGCGCTCAGAGAAGGAGCTGAGGAA TTTGCAACGAGAGATTGAAATAATGCGGGGTCTGCGGCATCCCAACATTGTGCATATGCTTGACAGCTTT GAAACTGATAAAGAGGTGGTGGTGGTGACAGACTATGCTGAGGGAGAGCTCTTTCAGATCCTAGAAGATG ACGGAAAACTTCCTGAAGACCAGGTTCAGGCCATTGCTGCCCAGTTGGTGTCAGCCCTGTACTATCTGCA TTCCCACCGCATCCTACACCGAGATATGAAGCCTCAGAACATCCTCCTCGCCAAGGGTGGTGGCATCAAG CTCTGTGACTTTGGATTTGCCCGGGCTATGAGCACCAATACAATGGTGCTGACATCCATCAAAGGCACAC CACTCTATATGTCTCCAGAGCTGGTGGAGGAGCGACCATACGACCACACAGCGGACCTCTGGTCTGTTGG CTGCATACTATATGAACTGGCAGTAGGCACCCCTCCCTTCTATGCTACAAGCATCTTTCAGCTGGTCAGC CTCATTCTCAAGGACCCTGTGCGCTGGCCCTCAACCATCAGTCCCTGCTTTAAGAACTTCCTGCAGGGAC TGCTCACCAAAGACCCACGGCAGCGACTGTCCTGGCCAGACCTCTTATATCACCCCTTTATTGCTGGTCA TGTCACCATAATAACTGAGCCAGCAGGCCCAGATTTGGGGACCCCATTCACCAGCCGCCTACCCCCAGAA CTTCAGGTCCTAAAGGACGAACAGGCCCATCGGTTGGCCCCCAAGGGTAATCAGTCTCGCATCTTGACTC AGGCCTATAAACGCATGGCTGAGGAGGCCATGCAGAAGAAACATCAGAACACAGGACCTGCCCTTGAGCA AGAGGACAAGACCAGCAAGGTGGCTCCTGGCACAGCCCCTCTGCCCAGACTCGGGGCCACTCCTCAGGAA TCAAGCCTCCTGGCCGGGATCTTAGCCTCAGAATTGAAGAGCAGCTGGGCTAAATCAGGGACTGGAGAGG TGCCCTCTGCACCTCGGGAAAACCGGACCACCCCAGATTGTGAACGAGCATTCCCAGAGGAGAGGCCAGA GGTGCTGGGCCAGCGGAGCACTGATGTAGTGGACCTGGAAAATGAGGAGCCAGACAGTGACAATGAGTGG CAGCACCTGCTAGAGACCACTGAGCCTGTGCCTATTCAACTGAAGGCTCCTCTCACCTTGCTGTGTAATC CTGACTTCTGCCAGCGCATCCAGAGTCAGCTGCATGAAGCTGGAGGGCAGATCCTGAAAGGCATCTTGGA GGGTGCTTCCCACATCCTGCCTGCATTCCGGGTCCTGAGCAGTCTTCTCTCCAGCTGCAGTGATTCTGTT GCCTTGTATTCCTTCTGCCGGGAGGCAGGGCTTCCTGGGCTGCTGCTGAGTCTACTCAGGCACAGTCAGG AGAGCAACAGCCTCCAGCAGCAATCTTGGTATGGGACCTTCTTACAGGACCTGATGGCTGTGATTCAGGC CTACTTTGCCTGTACCTTCAATCTGGAGAGGAGCCAGACAAGTGACAGCCTGCAGGTGTTTCAGGAGGCT GCCAACCTTTTTCTGGACCTGTTGGGGAAACTGCTGGCCCAACCAGATGACTCTGAGCAGACTTTGCGGA GGGACAGCCTTATGTGCTTTACTGTCCTGTGCGAAGCCATGGATGGGAACAGCCGGGCCATCTCCAAAGC CTTTTACTCCAGCTTGCTGACGACACAGCAGGTTGTCTTGGATGGGCTCCTTCATGGCTTGACAGTTCCA CAGCTCCCTGTCCACACTCCCCAAGGAGCCCCGCAAGTGAGCCAGCCACTGCGAGAGCAGAGTGAGGATA TACCTGGAGCCATTTCCTCTGCCCTGGCAGCCATATGCACTGCTCCTGTGGGACTGCCCGACTGCTGGGA TGCCAAGGAGCAGGTCTGTTGGCATTTGGCAAATCAGCTAACTGAAGACAGCAGCCAGCTCAGGCCATCC CTCATCTCTGGCCTGCAGCATCCCATCCTGTGCCTGCACCTTCTCAAGGTTCTATACTCCTGCTGCCTTG TCAGTGAGGGCCTGTGCCGTCTTCTGGGGCAGGAGCCCCTGGCCTTGGAATCCCTGTTTATGTTGATTCA GGGCAAGGTAAAAGTAGTAGATTGGGAAGAGTCTACTGAAGTGACACTCTACTTCCTCTCCCTTCTTGTC TTTCGGCTCCAAAACCTGCCTTGTGGAATGGAGAAGCTAGGCAGTGACGTTGCTACTCTCTTTACCCATT CGCATGTCGTCTCTCTTGTGAGTGCAGCAGCCTGTCTATTGGGACAGCTTGGTCAGCAAGGGGTGACCTT TGACCTCCAGCCCATGGAATGGATGGCTGCAGCCACACATGCCTTGTCTGCCCCTGCAGAGCTCCTCACT GAGCAGGGGAAGGCTAGCCTAATCAGGGATATGTCCAGTTCAGAAATGTGGACCGTTTTGTGGCACCGCT TCTCCATGGTCCTGAGGCTCCCCGAGGAGGCATCTGCACAGGAAGGGGAGCTTTCGCTATCCAGTCCACC AAGCCCTGAGCCAGACTGGACACTGATTTCTCCCCAGGGCATGGCAGCCCTGCTGAGCCTGGCCATGGCC ACCTTTACCCAGGAGCCCCAGTTATGCCTGAGCTGCCTGTCCCAGCATGGAAGTATCCTCATGTCCATCC TGAAGCATCTGCTTTGCCCCAGCTTCCTGAATCAACTGCGCCAGGCGCCTCATGGGTCTGAGTTTCTCCC TGTCGTGGTGCTCTCTGTCTGCCAGCTCCTTTGCTTCCCCTTTGCGCTGGACATGGATGCTGACCTCCTT ATAGGTGTCTTGGCCGACCTCAGGGACTCAGAAGTTGCAGCCCATCTGCTGCAGGTCTGCTGCTACCATC TTCCGTTGATGCAAGTGGAGCTGCCCATCAGCCTTCTCACACGCCTGGCCCTCATGGATCCCACCTCTCT CAACCAGTTTGTGAACACAGTGTCTGCCTCCCCTAGAACCATCGTCTCGTTTCTCTCAGTTGCCCTCCTG AGTGACCAGCCACTGTTGACCTCCGACCTTCTCTCTCTGCTGGCCCATACTGCCAGGGTCCTGTCTCCCA GCCACTTGTCCTTTATCCAAGAGCTTCTGGCTGGCTCTGATGAATCCTATCGGCCCCTGCGCAGCCTCCT GGGCCACCCAGAGAATTCTGTGCGGGCACACACTTATAGGCTCCTGGGACACTTGCTCCAACACAGCATG GCCCTGCGTGGGGCACTGCAGAGCCAGTCTGGACTGCTCAGCCTTCTGCTGCTTGGGCTTGGAGACAAGG ATCCTGTTGTGCGGTGCAGTGCCAGCTTTGCTGTGGGCAATGCAGCCTACCAGGCTGGTCCTCTGGGACC TGCCCTGGCAGCTGCAGTGCCCAGTATGACCCAGCTGCTTGGAGATCCTCAGGCTGGTATCCGGCGCAAT GTTGCATCAGCTCTGGGCAACTTGGGACCTGAAGGTTTGGGAGAGGAGCTGTTACAGTGCGAAGTACCCC AGCGGCTCCTAGAAATGGCATGTGGAGACCCCCAGCCAAATGTGAAGGAGGCTGCCCTCATTGCCCTCCG GAGCCTGCAACAGGAGCCTGGCATCCATCAGGTACTGGTGTCCCTGGGTGCCAGTGAGAAACTATCCTTG CTCTCTCTGGGGAATCAGTCACTGCCACACAGCAGTCCTAGGCCTGCCTCTGCCAAACACTGCAGGAAAC TCATTCACCTCCTGAGGCCAGCCCATAGCATGTGA |
Restriction Sites | SgfI-MluI |
ACCN | NM_001243313 |
ORF Size | 3885 bp |
OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
Reference Data | |
RefSeq | NM_001243313.1, NP_001230242.1 |
RefSeq Size | 4883 |
RefSeq ORF | 3885 |
Locus ID | 27148 |
Protein Families | Druggable Genome, Protein Kinase |
Protein Pathways | Basal cell carcinoma, Hedgehog signaling pathway, Pathways in cancer |
Gene Summary | This gene encodes a member of the serine/threonine kinase family of enzymes. This family member is similar to a Drosophila protein that plays a key role in the Hedgehog signaling pathway. This human protein is a positive regulator of the GLI zinc-finger transcription factors. Knockout studies of the homologous mouse gene suggest that defects in this human gene may lead to congenital hydrocephalus, possibly due to a functional defect in motile cilia. Because Hedgehog signaling is frequently activated in certain kinds of gastrointestinal cancers, it has been suggested that this gene is a target for the treatment of these cancers. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Aug 2011] Transcript Variant: This variant (2) uses an alternate in-frame splice site in the central coding region, compared to variant 1, resulting in an isoform (2, also known as L-FUdelta24) that is shorter than isoform 1. |
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