STK36 (NM_001243313) Human Untagged Clone

CAT#: SC330114

STK36 (untagged) - Homo sapiens serine/threonine kinase 36 (STK36), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: STK36
• Synonyms: FU
• Vector: pCMV6 series
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_001243313, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGGAAAAGTACCACGTGTTGGAGATGATTGGAGAAGGCTCTTTTGGGAGGGTGTACAAGGGTCGAAGAA
  AATACAGTGCTCAGGTCGTGGCCCTGAAGTTCATCCCAAAATTGGGGCGCTCAGAGAAGGAGCTGAGGAA
  TTTGCAACGAGAGATTGAAATAATGCGGGGTCTGCGGCATCCCAACATTGTGCATATGCTTGACAGCTTT
  GAAACTGATAAAGAGGTGGTGGTGGTGACAGACTATGCTGAGGGAGAGCTCTTTCAGATCCTAGAAGATG
  ACGGAAAACTTCCTGAAGACCAGGTTCAGGCCATTGCTGCCCAGTTGGTGTCAGCCCTGTACTATCTGCA
  TTCCCACCGCATCCTACACCGAGATATGAAGCCTCAGAACATCCTCCTCGCCAAGGGTGGTGGCATCAAG
  CTCTGTGACTTTGGATTTGCCCGGGCTATGAGCACCAATACAATGGTGCTGACATCCATCAAAGGCACAC
  CACTCTATATGTCTCCAGAGCTGGTGGAGGAGCGACCATACGACCACACAGCGGACCTCTGGTCTGTTGG
  CTGCATACTATATGAACTGGCAGTAGGCACCCCTCCCTTCTATGCTACAAGCATCTTTCAGCTGGTCAGC
  CTCATTCTCAAGGACCCTGTGCGCTGGCCCTCAACCATCAGTCCCTGCTTTAAGAACTTCCTGCAGGGAC
  TGCTCACCAAAGACCCACGGCAGCGACTGTCCTGGCCAGACCTCTTATATCACCCCTTTATTGCTGGTCA
  TGTCACCATAATAACTGAGCCAGCAGGCCCAGATTTGGGGACCCCATTCACCAGCCGCCTACCCCCAGAA
  CTTCAGGTCCTAAAGGACGAACAGGCCCATCGGTTGGCCCCCAAGGGTAATCAGTCTCGCATCTTGACTC
  AGGCCTATAAACGCATGGCTGAGGAGGCCATGCAGAAGAAACATCAGAACACAGGACCTGCCCTTGAGCA
  AGAGGACAAGACCAGCAAGGTGGCTCCTGGCACAGCCCCTCTGCCCAGACTCGGGGCCACTCCTCAGGAA
  TCAAGCCTCCTGGCCGGGATCTTAGCCTCAGAATTGAAGAGCAGCTGGGCTAAATCAGGGACTGGAGAGG
  TGCCCTCTGCACCTCGGGAAAACCGGACCACCCCAGATTGTGAACGAGCATTCCCAGAGGAGAGGCCAGA
  GGTGCTGGGCCAGCGGAGCACTGATGTAGTGGACCTGGAAAATGAGGAGCCAGACAGTGACAATGAGTGG
  CAGCACCTGCTAGAGACCACTGAGCCTGTGCCTATTCAACTGAAGGCTCCTCTCACCTTGCTGTGTAATC
  CTGACTTCTGCCAGCGCATCCAGAGTCAGCTGCATGAAGCTGGAGGGCAGATCCTGAAAGGCATCTTGGA
  GGGTGCTTCCCACATCCTGCCTGCATTCCGGGTCCTGAGCAGTCTTCTCTCCAGCTGCAGTGATTCTGTT
  GCCTTGTATTCCTTCTGCCGGGAGGCAGGGCTTCCTGGGCTGCTGCTGAGTCTACTCAGGCACAGTCAGG
  AGAGCAACAGCCTCCAGCAGCAATCTTGGTATGGGACCTTCTTACAGGACCTGATGGCTGTGATTCAGGC
  CTACTTTGCCTGTACCTTCAATCTGGAGAGGAGCCAGACAAGTGACAGCCTGCAGGTGTTTCAGGAGGCT
  GCCAACCTTTTTCTGGACCTGTTGGGGAAACTGCTGGCCCAACCAGATGACTCTGAGCAGACTTTGCGGA
  GGGACAGCCTTATGTGCTTTACTGTCCTGTGCGAAGCCATGGATGGGAACAGCCGGGCCATCTCCAAAGC
  CTTTTACTCCAGCTTGCTGACGACACAGCAGGTTGTCTTGGATGGGCTCCTTCATGGCTTGACAGTTCCA
  CAGCTCCCTGTCCACACTCCCCAAGGAGCCCCGCAAGTGAGCCAGCCACTGCGAGAGCAGAGTGAGGATA
  TACCTGGAGCCATTTCCTCTGCCCTGGCAGCCATATGCACTGCTCCTGTGGGACTGCCCGACTGCTGGGA
  TGCCAAGGAGCAGGTCTGTTGGCATTTGGCAAATCAGCTAACTGAAGACAGCAGCCAGCTCAGGCCATCC
  CTCATCTCTGGCCTGCAGCATCCCATCCTGTGCCTGCACCTTCTCAAGGTTCTATACTCCTGCTGCCTTG
  TCAGTGAGGGCCTGTGCCGTCTTCTGGGGCAGGAGCCCCTGGCCTTGGAATCCCTGTTTATGTTGATTCA
  GGGCAAGGTAAAAGTAGTAGATTGGGAAGAGTCTACTGAAGTGACACTCTACTTCCTCTCCCTTCTTGTC
  TTTCGGCTCCAAAACCTGCCTTGTGGAATGGAGAAGCTAGGCAGTGACGTTGCTACTCTCTTTACCCATT
  CGCATGTCGTCTCTCTTGTGAGTGCAGCAGCCTGTCTATTGGGACAGCTTGGTCAGCAAGGGGTGACCTT
  TGACCTCCAGCCCATGGAATGGATGGCTGCAGCCACACATGCCTTGTCTGCCCCTGCAGAGCTCCTCACT
  GAGCAGGGGAAGGCTAGCCTAATCAGGGATATGTCCAGTTCAGAAATGTGGACCGTTTTGTGGCACCGCT
  TCTCCATGGTCCTGAGGCTCCCCGAGGAGGCATCTGCACAGGAAGGGGAGCTTTCGCTATCCAGTCCACC
  AAGCCCTGAGCCAGACTGGACACTGATTTCTCCCCAGGGCATGGCAGCCCTGCTGAGCCTGGCCATGGCC
  ACCTTTACCCAGGAGCCCCAGTTATGCCTGAGCTGCCTGTCCCAGCATGGAAGTATCCTCATGTCCATCC
  TGAAGCATCTGCTTTGCCCCAGCTTCCTGAATCAACTGCGCCAGGCGCCTCATGGGTCTGAGTTTCTCCC
  TGTCGTGGTGCTCTCTGTCTGCCAGCTCCTTTGCTTCCCCTTTGCGCTGGACATGGATGCTGACCTCCTT
  ATAGGTGTCTTGGCCGACCTCAGGGACTCAGAAGTTGCAGCCCATCTGCTGCAGGTCTGCTGCTACCATC
  TTCCGTTGATGCAAGTGGAGCTGCCCATCAGCCTTCTCACACGCCTGGCCCTCATGGATCCCACCTCTCT
  CAACCAGTTTGTGAACACAGTGTCTGCCTCCCCTAGAACCATCGTCTCGTTTCTCTCAGTTGCCCTCCTG
  AGTGACCAGCCACTGTTGACCTCCGACCTTCTCTCTCTGCTGGCCCATACTGCCAGGGTCCTGTCTCCCA
  GCCACTTGTCCTTTATCCAAGAGCTTCTGGCTGGCTCTGATGAATCCTATCGGCCCCTGCGCAGCCTCCT
  GGGCCACCCAGAGAATTCTGTGCGGGCACACACTTATAGGCTCCTGGGACACTTGCTCCAACACAGCATG
  GCCCTGCGTGGGGCACTGCAGAGCCAGTCTGGACTGCTCAGCCTTCTGCTGCTTGGGCTTGGAGACAAGG
  ATCCTGTTGTGCGGTGCAGTGCCAGCTTTGCTGTGGGCAATGCAGCCTACCAGGCTGGTCCTCTGGGACC
  TGCCCTGGCAGCTGCAGTGCCCAGTATGACCCAGCTGCTTGGAGATCCTCAGGCTGGTATCCGGCGCAAT
  GTTGCATCAGCTCTGGGCAACTTGGGACCTGAAGGTTTGGGAGAGGAGCTGTTACAGTGCGAAGTACCCC
  AGCGGCTCCTAGAAATGGCATGTGGAGACCCCCAGCCAAATGTGAAGGAGGCTGCCCTCATTGCCCTCCG
  GAGCCTGCAACAGGAGCCTGGCATCCATCAGGTACTGGTGTCCCTGGGTGCCAGTGAGAAACTATCCTTG
  CTCTCTCTGGGGAATCAGTCACTGCCACACAGCAGTCCTAGGCCTGCCTCTGCCAAACACTGCAGGAAAC
  TCATTCACCTCCTGAGGCCAGCCCATAGCATGTGA
  
  
• Restriction Sites: SgfI-MluI
• ACCN: NM_001243313
• ORF Size: 3885 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_001243313.1, NP_001230242.1
• RefSeq Size: 4883
• RefSeq ORF: 3885
• Locus ID: 27148
• Protein Families: Druggable Genome, Protein Kinase
• Protein Pathways: Basal cell carcinoma, Hedgehog signaling pathway, Pathways in cancer
• Gene Summary: This gene encodes a member of the serine/threonine kinase family of enzymes. This family member is similar to a Drosophila protein that plays a key role in the Hedgehog signaling pathway. This human protein is a positive regulator of the GLI zinc-finger transcription factors. Knockout studies of the homologous mouse gene suggest that defects in this human gene may lead to congenital hydrocephalus, possibly due to a functional defect in motile cilia. Because Hedgehog signaling is frequently activated in certain kinds of gastrointestinal cancers, it has been suggested that this gene is a target for the treatment of these cancers. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Aug 2011]
  Transcript Variant: This variant (2) uses an alternate in-frame splice site in the central coding region, compared to variant 1, resulting in an isoform (2, also known as L-FUdelta24) that is shorter than isoform 1.