HERC3 (NM_001271602) Human Untagged Clone

CAT#: SC330944

HERC3 (untagged) - Homo sapiens HECT and RLD domain containing E3 ubiquitin protein ligase 3 (HERC3), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: HERC3
• Vector: pCMV6 series
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_001271602, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGACTACTGAGGATTCTGTGGCAGTGCCCAGGTTAATACAAAAGCTGAACCAGCAAACAATATTACAAG
  TTTCCTGTGGCAACTGGCATTGCTTGGCTCTTGCGGCTGATGGCCAGTTCTTCACCTGGGGAAAGAACAG
  CCATGGGCAGCTTGGCTTAGGGAAGGAGTTCCCCTCCCAAGCCAGCCCACAGAGGGTGAGGTCCCTGGAG
  GGGATCCCACTGGCTCAGGTGGCTGCCGGAGGGGCTCACAGCTTTGCCCTGTCTCTCTCAGGAGCTGTTT
  TTGGCTGGGGGATGAATAATGCCGGGCAGCTAGGGCTCAGTGATGAAAAAGATCGAGAATCTCCATGCCA
  TGTAAAACTCTTACGCACGCAAAAAGTTGTCTATATTAGTTGTGGAGAAGAACACACAGCAGTTCTCACA
  AAGAGTGGAGGTGTGTTTACCTTTGGCGCTGGTTCCTGTGGGCAACTTGGACACGACTCCATGAATGATG
  AGGTTAACCCTAGAAGAGTTCTAGAGCTGATGGGTAGTGAAGTAACTCAAATTGCTTGTGGCAGACAACA
  TACCCTAGCCTTCGTGCCTTCTTCTGGACTCATCTATGCATTTGGTTGTGGAGCAAGAGGTCAATTAGGA
  ACTGGGCACACTTGTAATGTTAAGTGCCCATCTCCTGTCAAGGGTTACTGGGCTGCCCACAGTGGCCAGC
  TTTCAGCCCGAGCTGATCGCTTTAAATATCATATCGTTAAGCAGATCTTCTCTGGAGGAGACCAGACTTT
  TGTACTTTGCTCCAAATACGAGAATTATTCTCCTGCTGTTGACTTCAGGACTATGAACCAAGCACATTAT
  ACCAGTTTAATAAATGATGAAACCATAGCAGTTTGGAGACAAAAACTCTCAGAACACAACAATGCAAATA
  CAATCAATGGTGTTGTTCAGATATTATCTTCTGCAGCCTGTTGGAATGGAAGTTTTCTTGAAAAAAAAAT
  TGATGAACATTTTAAAACGAGTCCCAAAATCCCTGGGATTGACCTGAACTCAACTAGGGTGTTATTTGAG
  AAGTTAATGAACTCTCAGCACTCCATGATTCTAGAACAGATTTTGAACAGTTTTGAAAGTTGTCTGATTC
  CCCAGTTGTCAAGCTCACCACCAGATGTTGAAGCCATGAGAATCTATTTAATACTACCTGAGTTTCCCCT
  ACTCCAGGATTCCAAGTATTATATAACATTGACTATTCCCTTGGCTATGGCCATTCTTCGGCTGGATACA
  AACCCCAGCAAAGTACTAGATAACTGGTGGTCTCAGGTATGCCCGAAATATTTCATGAAGCTGGTAAACC
  TCTATAAAGGTGCAGTCCTTTATCTACTGAGGGGAAGAAAGACATTCTTAATTCCCGTACTGTTTAACAA
  TTATATCACAGCAGCTCTCAAACTCTTGGAGAAGTTATATAAGGTAAATCTTAAAGTGAAGCATGTGGAA
  TATGATACATTTTACATTCCTGAGATTTCCAATCTCGTGGACATTCAGGAAGACTACCTCATGTGGTTCT
  TGCATCAAGCAGGGATGAAGGCTAGACCATCAATAATACAGGATACTGTAACACTTTGTTCCTACCCTTT
  CATCTTTGATGCCCAAGCCAAGACCAAAATGTTACAGACAGATGCTGAACTACAGATGCAGGTGGCAGTC
  AATGGAGCCAACCTGCAGAATGTCTTCATGCTTCTCACCCTGGAGCCTCTGCTGGCCAGAAGCCCCTTCC
  TGGTCCTTCACGTTCGCAGGAACAACCTTGTTGGAGATGCCCTAAGAGAGCTGAGCATTCATTCTGATAT
  TGATTTGAAAAAGCCTCTCAAAGTAATCTTTGATGGTGAAGAAGCAGTGGATGCCGGTGGTGTTACAAAG
  GAATTTTTTCTTTTGCTGTTAAAAGAACTTTTGAATCCCATCTATGGAATGTTTACCTACTATCAAGATT
  CAAATCTCTTGTGGTTTTCAGACACGTGTTTTGTAGAGCACAACTGGTTTCACTTGATTGGTATAACCTG
  TGGACTAGCTATCTACAACTCCACTGTGGTCGATCTCCACTTCCCATTGGCTCTCTACAAGAAGTTACTC
  AATGTAAAGCCTGGCTTGGAAGACTTAAAGGAGTTGTCACCCACTGAAGGAAGGAGTCTCCAAGAGCTTT
  TAGATTACCCCGGGGAGGATGTGGAGGAGACTTTCTGCCTCAACTTCACGATCTGCCGAGAAAGCTATGG
  AGTGATTGAACAGAAGAAGCTGATACCTGGGGGAGATAATGTAACTGTGTGCAAGGATAACAGGCAGGAA
  TTTGTGGATGCTTATGTGAATTATGTCTTCCAAATCTCAGTTCATGAATGGTACACAGCCTTCTCTAGTG
  GCTTCCTAAAGGTGTGTGGTGGCAAAGTACTTGAGCTCTTCCAGCCTTCAGAACTGAGGGCTATGATGGT
  GGGGAACAGCAACTACAACTGGGAAGAACTGGAAGAGACTGCCATCTACAAGGGAGATTACTCGGCCACA
  CATCCCACTGTAAAACTATTTTGGGAAACATTTCATGAGTTTCCATTGGAAAAGAAGAAGAAGTTTCTCT
  TGTTCCTGACAGGCAGCGATCGGATTCCCATCTACGGCATGGCCAGTCTGCAGATTGTCATCCAGTCCAC
  AGCCAGCGGGGAGGAGTACTTGCCGGTGGCCCACACTTGCTACAACCTTCTTGACCTCCCCAAGTACAGC
  AGCAAAGAGATTCTGAGTGCCCGGCTGACCCAGGCCCTTGACAACTATGAAGGGTTTAGTTTGGCCTGA
  
  
• Restriction Sites: SgfI-MluI
• ACCN: NM_001271602
• ORF Size: 2799 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_001271602.1, NP_001258531.1
• RefSeq Size: 4730
• RefSeq ORF: 2799
• Locus ID: 8916
• Protein Families: Druggable Genome
• Protein Pathways: Ubiquitin mediated proteolysis
• Gene Summary: This gene encodes a member the HERC ubiquitin ligase family. The encoded protein is located in the cytosol and binds ubiquitin via a HECT domain. Mutations in this gene have been associated with colorectal and gastric carcinomas. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Oct 2012]
  Transcript Variant: This variant (2) lacks an alternate 5' exon and portion of the 5' coding region. These differences cause translation initiation at a downstream AUG and result in an isoform (2) which has a shorter N-terminus, compared to isoform 1.