LRBA (NM_001199282) Human Untagged Clone

CAT#: SC331290

LRBA (untagged) - Homo sapiens LPS-responsive vesicle trafficking, beach and anchor containing (LRBA), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: LRBA
• Synonyms: BGL; CDC4L; CVID8; LAB300; LBA
• Vector: pCMV6 series
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_001199282, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGGCTAGCGAAGACAATCGTGTCCCTTCCCCGCCACCAACAGGTGATGACGGGGGAGGTGGAGGGAGAG
  AAGAAACCCCTACTGAAGGGGGTGCATTGTCTCTGAAACCAGGGCTCCCCATCAGGGGCATCAGAATGAA
  ATTTGCCGTGTTGACCGGTTTGGTTGAAGTTGGAGAAGTATCCAATAGGGATATTGTAGAAACTGTCTTT
  AACCTGTTGGTAGGAGGACAGTTTGATCTGGAAATGAATTTCATTATCCAAGAAGGTGAGAGTATTAACT
  GCATGGTGGACCTACTGGAAAAATGTGACATTACGTGCCAAGCAGAAGTCTGGAGCATGTTTACAGCCAT
  TCTGAAGAAAAGCATACGGAATCTTCAAGTCTGCACTGAAGTAGGCCTTGTTGAAAAAGTGCTTGGGAAA
  ATTGAAAAAGTTGACAATATGATAGCAGATCTTTTGGTTGACATGTTGGGAGTGCTGGCTAGCTATAATT
  TGACAGTTCGCGAGCTAAAGCTTTTCTTCAGTAAACTTCAAGGAGATAAAGGACGATGGCCTCCACATGC
  TGGGAAGTTGCTGTCTGTGTTAAAGCATATGCCTCAGAAGTATGGTCCTGATGCCTTTTTTAACTTTCCA
  GGAAAGAGTGCTGCAGCTATTGCATTACCTCCTATAGCCAAATGGCCATACCAGAATGGTTTTACATTTC
  ATACATGGCTTAGAATGGATCCTGTAAATAACATCAATGTAGATAAGGATAAACCATATTTGTATTGTTT
  CAGAACCAGCAAAGGTCTTGGCTATTCTGCTCATTTTGTTGGAGGCTGTTTGATTGTAACATCAATAAAG
  TCAAAAGGAAAAGGCTTTCAACACTGTGTGAAATTTGATTTCAAGCCACAAAAGTGGTATATGGTTACCA
  TAGTACACATCTATAACCGATGGAAGAATAGTGAACTTCGATGTTATGTGAATGGTGAGCTGGCTTCCTA
  TGGAGAGATAACATGGTTTGTCAACACTAGCGATACCTTTGACAAATGTTTCCTGGGCTCATCAGAAACA
  GCAGATGCTAATAGAGTATTCTGTGGTCAGATGACTGCAGTTTACCTTTTCAGTGAAGCTCTAAATGCAG
  CTCAGATATTTGCTATTTATCAGTTGGGCCTGGGATACAAGGGTACATTTAAATTCAAAGCAGAAAGCGA
  CCTTTTCCTTGCTGAGCATCACAAACTTTTATTGTACGATGGGAAACTCTCTAGTGCCATTGCATTCACG
  TACAATCCACGGGCTACAGATGCCCAGCTTTGTCTTGAATCATCTCCTAAGGACAACCCTTCAATTTTTG
  TTCATTCACCACATGCACTCATGCTCCAGGATGTAAAGGCAGTTTTAACACATTCCATCCAAAGTGCAAT
  GCATTCAATTGGAGGAGTACAAGTACTATTTCCACTTTTTGCACAGTTGGATTACAGGCAATATTTGTCT
  GATGAGATTGATTTGACTATATGTTCAACCTTGCTGGCCTTTATCATGGAATTGTTGAAGAACTCAATTG
  CTATGCAGGAACAGATGCTTGCCTGTAAGGGCTTCTTGGTAATAGGATATAGCCTTGAAAAGTCTTCCAA
  ATCTCATGTTAGCAGAGCAGTACTTGAACTTTGCCTTGCATTTTCAAAATATCTGAGTAATCTGCAGAAT
  GGGATGCCCCTGCTCAAGCAATTGTGTGATCACGTTCTTCTTAATCCTGCCATATGGATTCATACCCCAG
  CCAAGGTTCAACTGATGCTCTATACTTATCTGTCCACGGAATTCATTGGTACAGTCAACATATATAACAC
  CATTCGGAGAGTTGGAACAGTGCTTCTCATCATGCACACGCTGAAGTACTACTACTGGGCAGTGAATCCT
  CAGGATCGAAGTGGTATCACCCCAAAAGGATTAGATGGACCGCGACCTAATCAAAAAGAAATGCTTTCTC
  TACGAGCATTCTTGTTGATGTTCATTAAGCAATTAGTGATGAAGGATTCTGGAGTAAAGGAAGATGAATT
  ACAGGCCATTCTTAATTACCTACTGACTATGCATGAGGATGACAATCTAATGGATGTCCTACAGCTGCTT
  GTTGCATTAATGTCAGAACACCCTAACTCTATGATTCCTGCTTTTGACCAAAGGAATGGGTTACGTGTTA
  TCTACAAACTTCTGGCATCGAAAAGTGAAGGAATCAGGGTACAAGCTCTTAAGGCAATGGGTTATTTTTT
  AAAACATCTGGCCCCAAAGAGGAAAGCAGAAGTCATGCTTGGACATGGATTGTTTTCATTGCTAGCTGAA
  AGGCTCATGCTTCAGACAAATTTAATCACAATGACCACATATAATGTGCTGTTTGAGATTCTTATAGAAC
  AGATTGGTACTCAGGTGATACATAAACAGCATCCAGATCCTGATTCTTCAGTGAAGATACAAAACCCTCA
  GATACTAAAAGTAATTGCGACCCTACTTCGAAATTCTCCCCAGTGCCCAGAGAGCATGGAGGTTCGCAGA
  GCCTTTCTTTCTGACATGATTAAACTTTTTAATAACAGTAGAGAAAACAGGAGGAGCTTGCTACAATGCT
  CTGTGTGGCAAGAATGGATGCTTTCTCTCTGCTATTTTAATCCTAAGAATTCAGATGAGCAAAAGATAAC
  AGAAATGGTATACGCCATATTCAGAATCCTGCTTTACCATGCAGTCAAATATGAGTGGGGTGGCTGGCGT
  GTATGGGTAGACACTTTATCAATCACTCATTCAAAGGTCACTTTTGAAATACACAAAGAAAACCTTGCCA
  ATATATTTAGGGAACAGCAAGGAAAAGTTGATGAAGAAATAGGGCTGTGTTCTTCAACTTCAGTTCAAGC
  AGCCTCTGGCATTAGAAGGGATATTAATGTTTCAGTAGGATCCCAGCAACCAGATACGAAGGATTCTCCT
  GTCTGTCCTCATTTCACCACAAATGGTAATGAAAATTCAAGTATAGAGAAGACAAGTTCACTAGAATCTG
  CATCTAATATTGAACTGCAAACTACTAATACATCTTATGAAGAAATGAAAGCTGAGCAAGAAAATCAGGA
  GTTACCAGATGAAGGCACTTTGGAAGAAACACTGACAAATGAGACAAGGAATGCAGATGATTTAGAAGTA
  TCTTCTGACATAATAGAAGCTGTGGCTATTTCCTCTAATTCTTTTATAACAACTGGCAAAGATTCAATGA
  CTGTCAGTGAAGTAACTGCTTCTATAAGTTCTCCTTCAGAAGAGGATGCCTCAGAGATGCCAGAATTCTT
  GGATAAATCTATAGTAGAGGAAGAGGAAGATGATGATTATGTGGAACTGAAAGTAGAAGGCAGTCCTACT
  GAGGAAGCTAATCTACCCACAGAGCTCCAAGATAACAGTTTGTCTCCAGCTGCATCTGAAGCCGGTGAAA
  AACTGGACATGTTTGGTAATGATGACAAATTAATATTTCAAGAAGGAAAACCTGTTACTGAAAAGCAAAC
  TGATACTGAAACTCAAGATTCTAAAGATTCTGGAATTCAGACTATGACAGCATCAGGGTCTTCAGCTATG
  TCACCAGAAACTACTGTTTCCCAAATAGCTGTAGAATCAGACCTTGGTCAGATGCTGGAGGAAGGGAAGA
  AAGCAACTAACCTCACTAGAGAAACCAAATTAATTAATGATTGTCATGGTAGTGTCTCTGAGGCTTCTTC
  TGAGCAAAAGATTGCGAAGTTGGATGTTTCCAATGTTGCTACAGATACTGAGAGGCTGGAGTTGAAGGCC
  AGTCCCAACGTGGAAGCACCTCAACCTCATCGACATGTGCTTGAGATATCAAGGCAACATGAGCAGCCAG
  GGCAAGGAATAGCACCAGATGCAGTTAATGGACAAAGGAGGGATTCCAGATCTACTGTGTTTCGTATTCC
  TGAGTTCAACTGGTCTCAGATGCATCAACGTTTGCTCACTGATCTATTATTTTCAATAGAAACAGATATA
  CAGATGTGGAGAAGCCATTCAACAAAGACAGTTATGGACTTCGTGAATAGCAGTGATAATGTCATCTTTG
  TACACAACACAATTCATCTCATCTCTCAAGTGATGGACAATATGGTCATGGCTTGTGGGGGTATACTGCC
  ATTGCTTTCAGCTGCTACATCGGCTACACATGAACTGGAAAATATTGAACCTACTCAAGGCCTTTCAATA
  GAAGCCTCTGTGACATTTTTGCAGAGGCTAATTAGCCTTGTGGATGTGCTTATATTTGCAAGTTCTCTTG
  GCTTTACTGAAATTGAAGCTGAAAAAAGTATGTCATCTGGAGGAATTTTGCGGCAGTGTCTCCGACTAGT
  TTGTGCAGTCGCAGTAAGGAATTGCTTGGAGTGTCAACAGCATTCACAACTGAAAACTAGGGGAGATAAA
  GCCTTGAAACCAATGCATAGCCTTATTCCTTTAGGGAAATCTGCAGCGAAGAGCCCAGTGGACATTGTGA
  CTGGCGGTATATCTCCAGTAAGAGATCTTGACAGGCTTCTACAGGACATGGATATTAATCGGCTTAGGGC
  AGTTGTTTTCAGAGACATAGAGGATAGCAAACAAGCTCAATTTTTAGCCTTGGCAGTAGTATACTTTATC
  TCTGTTCTTATGGTCTCCAAGTACAGAGACATTTTGGAACCCCAAAATGAAAGGCATAGCCAGTCATGTA
  CAGAAACTGGCAGTGAAAATGAGAATGTATCACTCTCTGAAATCACACCAGCAGCATTCAGCACTTTAAC
  TACGGCATCAGTGGAAGAATCTGAAAGCACATCATCTGCTCGAAGGAGGGACTCAGGCATTGGGGAAGAA
  ACAGCCACTGGTTTAGGAAGCCATGTGGAAGTAACTCCTCACACAGCACCTCCTGGTGTCAGTGCAGGCC
  CAGATGCAATCAGCGAGGTGCTATCTACTCTTTCTTTAGAAGTCAATAAGTCTCCGGAAACCAAAAATGA
  TAGAGGAAATGACTTGGACACTAAGGCTACACCGTCAGTTTCAGTTTCAAAAAACGTCAATGTGAAAGAC
  ATTCTCCGAAGCTTGGTTAACATACCAGCAGATGGAGTCACAGTGGATCCTGCCCTTCTGCCACCAGCCT
  GCCTTGGAGCCCTTGGTGATCTATCTGTGGAACAACCCGTGCAGTTCAGATCTTTTGACAGAAGTGTCAT
  TGTTGCAGCAAAAAAGTCAGCAGTCTCACCTTCCACCTTTAATACAAGCATACCTACCAATGCTGTCAGT
  GTGGTTTCCTCAGTAGATTCAGCCCAAGCCTCAGATATGGGAGGAGAATCACCAGGCAGTAGATCATCTA
  ATGCAAAATTGCCCTCAGTTCCAACAGTTGATTCAGTTTCACAAGATCCGGTTTCAAATATGAGTATTAC
  AGAGAGGCTTGAACACGCTTTGGAAAAGGCAGCTCCTCTCCTTCGTGAGATTTTTGTGGATTTTGCACCT
  TTTCTTTCTCGGACACTTTTGGGTAGCCATGGACAAGAACTGCTTATAGAAGGAACAAGTCTGGTTTGCA
  TGAAGTCGAGTAGTTCAGTTGTGGAATTGGTTATGCTACTGTGTTCTCAGGAGTGGCAAAATTCTATTCA
  GAAGAATGCAGGCCTTGCTTTTATCGAACTTGTCAATGAAGGAAGGTTGCTTAGCCAGACAATGAAGGAT
  CATCTAGTAAGAGTAGCAAATGAAGCTGAATTTATCCTGAGCAGGCAGAGAGCAGAAGATATTCACAGAC
  ATGCGGAATTTGAGTCACTGTGTGCCCAGTATTCTGCAGACAAACGAGAAGATGAGAAGATGTGTGATCA
  TTTGATAAGAGCAGCAAAATATCGTGACCACGTGACAGCAACTCAACTAATCCAGAAAATTATCAACATT
  CTCACAGACAAGCATGGAGCCTGGGGAAATTCTGCAGTGAGTCGTCCTCTTGAGTTCTGGCGCCTTGACT
  ACTGGGAAGATGACTTGCGGCGCCGGCGACGATTTGTGCGTAACCCTCTAGGATCGACACATCCTGAAGC
  GACACTAAAAACAGCCGTGGAACATGCCACAGATGAAGATATCCTTGCTAAAGGAAAACAGTCCATCAGG
  AGTCAGGCTTTAGGAAATCAGAACTCAGAAAACGAGATCCTCCTGGAAGGCGATGATGATACTCTGTCAT
  CCGTGGATGAGAAAGATTTAGAGAATCTTGCCGGTCCTGTTAGCCTGAGCACACCAGCTCAGCTTGTGGC
  CCCCTCTGTTGTAGTAAAGGGCACTCTTTCTGTCACCTCCTCCGAACTCTATTTTGAGGTGGATGAAGAG
  GATCCTAACTTCAAAAAAATCGACCCCAAGATCTTGGCATATACAGAAGGGCTGCATGGAAAATGGCTGT
  TCACAGAGATACGATCAATCTTTTCTCGTCGTTATCTTTTGCAAAATACAGCCCTGGAGATCTTTATGGC
  AAACAGAGTTGCTGTGATGTTCAACTTCCCAGACCCTGCAACAGTAAAGAAAGTGGTTAACTATCTACCT
  CGTGTTGGCGTTGGAACAAGTTTTGGATTGCCTCAAACCAGACGTATTTCATTAGCTAGTCCACGTCAGC
  TTTTTAAGGCTTCTAATATGACCCAGCGATGGCAACACAGAGAGATATCTAATTTTGAGTACTTGATGTT
  TCTCAACACGATAGCAGGACGGAGTTATAATGACTTAAATCAGTATCCAGTGTTTCCTTGGGTCATCACT
  AATTATGAATCAGAAGAACTGGATCTTACCTTGCCCACCAACTTCAGAGATTTGTCCAAGCCAATAGGAG
  CTCTGAACCCAAAAAGAGCAGCATTCTTCGCTGAGCGTTATGAATCATGGGAAGATGATCAAGTTCCAAA
  GTTTCACTATGGTACTCATTACTCAACTGCAAGTTTTGTTCTTGCATGGCTGCTAAGAATAGAACCCTTT
  ACAACTTATTTCCTAAATTTGCAAGGAGGCAAATTTGATCATGCAGATCGAACTTTTTCATCAATTTCCA
  GAGCTTGGCGAAACAGTCAGCGTGATACCTCTGATATTAAGGAGTTGATCCCTGAATTTTATTATCTCCC
  TGAGATGTTTGTCAACTTCAATAATTATAATCTTGGAGTGATGGATGATGGGACAGTAGTGTCTGATGTC
  GAACTTCCTCCTTGGGCCAAAACCTCAGAAGAATTTGTTCACATAAACAGATTGGCCCTGGAGAGTGAAT
  TTGTTTCCTGCCAGCTTCACCAATGGATTGATCTCATTTTTGGCTATAAACAGCAAGGACCAGAAGCTGT
  CCGAGCCCTCAATGTGTTCTATTACTTGACCTATGAAGGAGCTGTCAATCTGAATTCAATAACTGATCCT
  GTGTTGAGAGAGGCTGTTGAAGCTCAAATCCGAAGTTTTGGACAGACTCCTTCTCAACTACTCATAGAGC
  CCCATCCTCCCAGAGGTTCTGCCATGCAAGTGAGTCCATTGATGTTCACAGACAAAGCCCAGCAGGATGT
  TATCATGGTCCTCAAGTTTCCCTCCAACTCCCCTGTTACTCACGTGGCAGCCAACACCCAGCCTGGTTTG
  GCAACTCCCGCTGTGATCACAGTCACTGCTAACAGGTTATTTGCGGTGAACAAATGGCACAACCTTCCTG
  CTCATCAAGGTGCTGTACAAGACCAGCCATACCAGCTGCCAGTGGAAATCGATCCTCTCATAGCCAGCAA
  TACAGGAATGCACAGGAGGCAAATCACTGACCTTTTAGACCAAAGTATTCAAGTGCATTCCCAGTGCTTT
  GTCATCACTTCAGACAACCGCTATATTCTCGTCTGTGGCTTCTGGGATAAAAGTTTCAGAGTCTATTCTA
  CAGACACAGGAAGATTGATCCAAGTGGTGTTTGGCCATTGGGATGTCGTCACTTGCCTTGCTCGTTCTGA
  GTCATATATTGGGGGAAATTGCTACATTCTCTCAGGGTCACGTGATGCAACTCTTTTGCTGTGGTATTGG
  AATGGAAAATGCAGTGGGATTGGAGATAACCCAGGTGAGACTGCTGCTCCTCGGGCCATTTTGACCGGCC
  ATGACTATGAGGTCACATGTGCTGCGGTGTGTGCGGAGCTAGGCCTGGTGTTGAGTGGTTCACAAGAAGG
  ACCATGTCTCATACATTCCATGAATGGAGACTTGTTGAGGACCTTGGAGGGTCCTGAAAACTGCCTGAAA
  CCAAAACTCATTCAGGCTTCAAGAGAGGGTCATTGTGTCATATTCTATGAAAACGGCCTCTTCTGTACAT
  TCAGTGTGAATGGAAAACTCCAGGCCACGATGGAAACAGATGATAACATAAGAGCCATCCAGCTGAGCCG
  AGATGGGCAGTACCTGCTCACAGGAGGAGACAGAGGAGTGGTCGTGGTCCGGCAGGTGTCGGACCTCAAG
  CAGCTCTTTGCCTATCCAGGATGTGACGCTGGAATCCGGGCCATGGCGCTGTCTTACGACCAGAGGTGCA
  TCATTTCTGGCATGGCTTCAGGAAGCATTGTGCTATTTTACAACGACTTTAACCGGTGGCATCATGAATA
  CCAAACCCGCTACTGA
  
  
• Restriction Sites: SgfI-MluI
• ACCN: NM_001199282
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_001199282.2, NP_001186211.2
• RefSeq Size: 9919 bp
• RefSeq ORF: 8556 bp
• Locus ID: 987
• Cytogenetics: 4q31.3
• Gene Summary: 'The protein encoded by this gene is a member of the WDL-BEACH-WD (WBW) gene family. Its expression is induced in B cells and macrophages by bacterial lipopolysaccharides (LPS). The encoded protein associates with protein kinase A and may be involved in leading intracellular vesicles to activated receptor complexes, which aids in the secretion and/or membrane deposition of immune effector molecules. Defects in this gene are associated with the disorder common variable immunodeficiency-8 with autoimmunity. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2012]'
  Transcript Variant: This variant (1) differs in the 5' UTR, lacks an alternate in-frame exon, and uses an alternate in-frame splice junction at the 3' end of an exon compared to variant 2. The resulting isoform (1) has the same N- and C-termini but is shorter compared to isoform 2.