PTPRN (NM_001199763) Human Untagged Clone

CAT#: SC331356

PTPRN (untagged) - Homo sapiens protein tyrosine phosphatase, receptor type, N (PTPRN), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: PTPRN
• Synonyms: IA-2; IA-2/PTP; IA2; ICA512; R-PTP-N
• Vector: pCMV6 series
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_001199763, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGCGGCGCCCGCGGCGGCCTGGGGGTCTCGGGGGATCCGGGGGTCTCCGGCTGCTCCTCTGCCTCCTGC
  TGCTGAGCAGCCGCCCGGGGGGCTGCAGCGCCGTTAGTGCCCACGGCTGTCTATTTGACCGCAGGCTCTG
  CTCTCACCTGGAAGTCTGTATTCAGGATGGCTTGTTTGGGCAGTGCCAGGTGGGAGTGGGGCAGGCCCGG
  CCCCTTTTGCAAGTCACCTCCCCAGTTCTCCAACGCTTACAAGGTGTGCTCCGACAACTCATGTCCCAAG
  GATTGTCCTGGCACGATGACCTCACCCAGTATGTGATCTCTCAGGAGATGGAGCGCATCCCCAGGCTTCG
  CCCCCCAGAGCCCCGTCCAAGGGACAGGTCTGGCTTGGCACCCAAGAGACCTGGTCCTGCTGGAGAGCTG
  CTTTTACAGGACATCCCCACTGGCTCCGCCCCTGCTGCCCAGCATCGGCTTCCACAACCACCAGTGGGCA
  AAGGTGGAGCTGGGGCCAGCTCCTCTCTGTCCCCTCTGCAGGCTGAGCTGCTCCCGCCTCTCTTGGAGCA
  CCTGCTGCTGCCCCCACAGCCTCCCCACCCTTCACTGAGTTACGAACCTGCCTTGCTGCAGCCCTACCTG
  TTCCACCAGTTTGGCTCCCGTGATGGCTCCAGGGTCTCAGAGGGCTCCCCAGGGATGGTCAGTGTCGGCC
  CCCTGCCCAAGGCTGAAGCCCCTGCCCTCTTCAGCAGAACTGCCTCCAAGGGCATATTTGGGGACCACCC
  TGGCCACTCCTACGGGGACCTTCCAGGGCCTTCACCTGCCCAGCTTTTTCAAGACTCTGGGCTGCTCTAT
  CTGGCCCAGGAGTTGCCAGCACCCAGCAGGGCCAGGGTGCCAAGGCTGCCAGAGCAAGGGAGCAGCAGCC
  GGGCAGAGGACTCCCCAGAGGGCTATGAGAAGGAAGGACTAGGGGATCGTGGAGAGAAGCCTGCTTCCCC
  AGCTGTGCAGCCAGATGCGGCTCTGCAGAGGCTGGCCGCTGTGCTGGCGGGCTATGGGGTAGAGCTGCGT
  CAGCTGACCCCTGAGCAGCTCTCCACACTCCTGACCCTGCTGCAGCTACTGCCCAAGGGTGCAGGAAGAA
  ATCCGGGAGGGGTTGTAAATGTTGGAGCTGATATCAAGAAAACAATGGAGGGGCCGGTGGAGGGCAGAGA
  CACAGCAGAGCTTCCAGCCCGCACATCCCCCATGCCTGGACACCCCACTGCCAGCCCTACCTCCAGTGAA
  GTCCAGCAGGTGCCAAGCCCTGTCTCCTCTGAGCCTCCCAAAGCTGCCAGACCCCCTGTGACACCTGTCC
  TGCTAGAGAAGAAAAGCCCACTGGGCCAGAGCCAGCCCACGGTGGCAGGACAGCCCTCAGCCCGCCCAGC
  AGCAGAGGAATATGGCTACATCGTCACTGATCAGAATGTGGTGGGACCAGCCCTCACCTTCCGCATCCGG
  CACAATGAGCAGAACCTGTCTTTGGCTGATGTGACCCAACAAGCAGGGCTGGTGAAGTCTGAACTGGAAG
  CACAGACAGGGCTCCAAATCTTGCAGACAGGAGTGGGACAGAGGGAGGAGGCAGCTGCAGTCCTTCCCCA
  AACTGCGCACAGCACCTCACCCATGCGCTCAGTGCTGCTCACTCTGGTGGCCCTGGCAGGTGTGGCTGGG
  CTGCTGGTGGCTCTGGCTGTGGCTCTGTGTGTGCGGCAGCATGCGCGGCAGCAAGACAAGGAGCGCCTGG
  CAGCCCTGGGGCCTGAGGGGGCCCATGGTGACACTACCTTTGAGTACCAGGACCTGTGCCGCCAGCACAT
  GGCCACGAAGTCCTTGTTCAACCGGGCAGAGGGTCCACCGGAGCCTTCACGGGTGAGCAGTGTGTCCTCC
  CAGTTCAGCGACGCAGCCCAGGCCAGCCCCAGCTCCCACAGCAGCACCCCGTCCTGGTGCGAGGAGCCGG
  CCCAAGCCAACATGGACATCTCCACGGGACACATGATTCTGGCATACATGGAGGATCACCTGCGGAACCG
  GGACCGCCTTGCCAAGGAGTGGCAGGCCCTCTGTGCCTACCAAGCAGAGCCAAACACCTGTGCCACCGCG
  CAGGGGGAGGGCAACATCAAAAAGAACCGGCATCCTGACTTCCTGCCCTATGACCATGCCCGCATAAAAC
  TGAAGGTGGAGAGCAGCCCTTCTCGGAGCGATTACATCAACGCCAGCCCCATTATTGAGCATGACCCTCG
  GATGCCAGCCTACATAGCCACGCAGGGCCCGCTGTCCCATACCATCGCAGACTTCTGGCAGATGGTGTGG
  GAGAGCGGCTGCACCGTCATCGTCATGCTGACCCCGCTGGTGGAGGATGGTGTCAAGCAGTGTGACCGCT
  ACTGGCCAGATGAGGGTGCCTCCCTCTACCACGTATATGAGGTGAACCTGGTGTCGGAGCACATCTGGTG
  CGAGGACTTTCTGGTGCGGAGCTTCTACCTGAAGAACGTGCAGACCCAGGAGACGCGCACGCTCACGCAG
  TTCCACTTCCTCAGCTGGCCGGCAGAGGGCACACCGGCCTCCACGCGGCCCCTGCTGGACTTCCGCAGGA
  AGGTGAACAAGTGCTACCGGGGCCGCTCCTGCCCCATCATCGTGCACTGCAGTGATGGTGCGGGGAGGAC
  CGGCACCTACATCCTCATCGACATGGTCCTGAACCGCATGGCAAAAGGAGTGAAGGAGATTGACATCGCT
  GCCACCCTGGAGCATGTCCGTGACCAGCGGCCTGGCCTTGTCCGCTCTAAGGACCAGTTTGAATTTGCCC
  TGACAGCCGTGGCGGAGGAAGTGAATGCCATCCTCAAGGCCCTGCCCCAGTGA
  
  
• Restriction Sites: SgfI-MluI
• ACCN: NM_001199763
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_001199763.1, NP_001186692.1
• RefSeq Size: 3712 bp
• RefSeq ORF: 2853 bp
• Locus ID: 5798
• Cytogenetics: 2q35
• Protein Families: Druggable Genome, Transmembrane
• Protein Pathways: Type I diabetes mellitus
• Gene Summary: 'The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and a single catalytic domain, and thus represents a receptor-type PTP. This PTP was found to be an autoantigen that is reactive with insulin-dependent diabetes mellitus (IDDM) patient sera, and thus may be a potential target of autoimmunity in diabetes mellitus. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Dec 2010]'
  Transcript Variant: This variant (2) lacks an in-frame exon in the coding region, compared to variant 1. The encoded isoform (2) is shorter than isoform 1.