PTPN7 (NM_001199797) Human Untagged Clone

CAT#: SC331363

PTPN7 (untagged) - Homo sapiens protein tyrosine phosphatase, non-receptor type 7 (PTPN7), transcript variant 3

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: PTPN7
• Synonyms: BPTP-4; HEPTP; LC-PTP; LPTP; PTPNI
• Vector: pCMV6 series
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_001199797, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGAACCGGCTGGGCTGCTGGCCCGCAAGGAGCCTGCCAAGGTCAGGCAGGGGCAGTGGGCAGAGGAGTC
  TTGGACTTGGGGGCCACCCTTCAGGTCCCAGGCATCCAGGCACCCCAGCAGCGAAGAGGACATGGGAGTC
  CCCTGGTGTGAGGGCCAGAGACTGTCCACTGTCTACCTCATGGCTGAGTGAGCCTCCCCTGGGCCCAGCA
  CCCCACCTCAGCATGGTCCAAGCCCATGGGGGGCGCTCCAGAGCACAGCCGTTGACCTTGTCTTTGGGGG
  CAGCCATGACCCAGCCTCCGCCTGAAAAAACGCCAGCCAAGAAGCATGTGCGACTGCAGGAGAGGCGGGG
  CTCCAATGTGGCTCTGATGCTGGACGTTCGGTCCCTGGGGGCCGTAGAACCCATCTGCTCTGTGAACACA
  CCCCGGGAGGTCACCCTACACTTTCTGCGCACTGCTGGACACCCCCTTACCCGCTGGGCCCTTCAGCGCC
  AGCCACCCAGCCCCAAGCAACTGGAAGAAGAATTCTTGAAGATCCCTTCAAACTTTGTCAGCCCCGAAGA
  CCTGGACATCCCTGGCCACGCCTCCAAGGACCGATACAAGACCATCTTGCCAAATCCCCAGAGCCGTGTC
  TGTCTAGGCCGGGCACAGAGCCAGGAGGACGGAGATTACATCAATGCCAACTACATCCGAGGCTATGACG
  GGAAGGAGAAGGTCTACATTGCCACCCAGGGCCCCATGCCCAACACTGTGTCGGACTTCTGGGAGATGGT
  GTGGCAAGAGGAAGTGTCCCTCATTGTCATGCTCACTCAGCTCCGAGAGGGCAAGGAGAAATGTGTCCAC
  TACTGGCCCACAGAAGAGGAAACCTATGGACCCTTCCAGATCCGCATCCAGGACATGAAAGAGTGCCCAG
  AATACACTGTGCGGCAGCTCACCATCCAGTACCAGGAAGAGCGCCGGTCAGTAAAGCACATCCTCTTTTC
  GGCCTGGCCAGACCATCAGACACCAGAATCAGCTGGGCCCCTGCTGCGCCTAGTGGCAGAGGTGGAGGAG
  AGCCCGGAGACAGCCGCCCACCCCGGGCCTATCGTAGTCCACTGCAGTGCAGGGATTGGCCGGACGGGCT
  GCTTCATCGCCACGCGAATTGGCTGTCAACAGCTGAAAGCCCGAGGAGAAGTGGACATTCTGGGTATTGT
  GTGCCAACTGCGGCTAGACAGAGGGGGGATGATCCAGACGGCAGAGCAGTACCAGTTCCTGCACCACACT
  TTGGCCCTGTATGCAGGCCAGCTGCCTGAGGAACCCAGCCCCTGA
  
  
• Restriction Sites: SgfI-MluI
• ACCN: NM_001199797
• ORF Size: 1305 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_001199797.1, NP_001186726.1
• RefSeq Size: 2926
• RefSeq ORF: 1305
• Locus ID: 5778
• Protein Families: Druggable Genome, Phosphatase
• Protein Pathways: MAPK signaling pathway
• Gene Summary: The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This gene is preferentially expressed in a variety of hematopoietic cells, and is an early response gene in lymphokine stimulated cells. The non-catalytic N-terminus of this PTP can interact with MAP kinases and suppress the MAP kinase activities. This PTP was shown to be involved in the regulation of T cell antigen receptor (TCR) signaling, which was thought to function through dephosphorylating the molecules related to MAP kinase pathway. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Dec 2010]
  Transcript Variant: This variant (3) lacks a segment in the 5' region, resulting in an upstream AUG start codon, as compared to variant 1. The resulting isoform (3) has a shorter and distinct N-terminus, as compared to isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.