RGS6 (NM_001204423) Human Untagged Clone

CAT#: SC331583

RGS6 (untagged) - Homo sapiens regulator of G-protein signaling 6 (RGS6), transcript variant 9

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: RGS6
• Synonyms: GAP; HA117; S914
• Vector: pCMV6 series
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_001204423, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGCAAGATGACAAGACAGGGGGTGTGCCCATCAGAACAGTCAAGAGCTTTCTCTCCAAAATCCCCAGTG
  TCGTCACAGGTACTGACATTGTGCAGTGGCTTATGAAGAACCTTTCCATTGAGGACCCAGTTGAAGCAAT
  ACACTTGGGGAGCCTTATCGCTGCCCAGGGCTACATCTTTCCAATCTCAGACCATGTTCTCACCATGAAG
  GATGATGGCACCTTTTATCGTTTCCAGGCTCCGTACTTCTGGCCTTCGAACTGCTGGGAACCTGAAAACA
  CTGACTATGCCATCTATCTCTGTAAGAGGACAATGCAAAATAAAGCAAGGCTGGAACTGGCAGATTATGA
  AGCAGAAAACTTAGCAAGACTCCAGAGGGCCTTTGCGAGGAAGTGGGAATTCATCTTTATGCAAGCAGAA
  GCACAAGTAAAGATTGACCGGAAAAAAGACAAGACAGAAAGGAAAATTTTGGATAGTCAAGAACGAGCCT
  TTTGGGATGTCCACAGGCCTGTGCCAGGCTGTGTGAACACAACAGAAATGGATATCCGAAAATGTCGACG
  TTTGAAGAATCCACAAAAGGTTAAAAAGTCCGTGTATGGCGTGACTGAAGAGTCCCAGGCACAGAGCCCG
  GTGCATGTACTCAGCCAACCAATCAGGAAAACAACAAAAGAGGACATCCGGAAACAGATAACATTTTTGA
  ACGCACAGATCGACAGACATTGTTTGAAAATGTCCAAAGTGGCTGAAAGTTTAATTGCCTACACGGAACA
  ATATGTGGAATATGACCCTTTGATAACACCAGCTGAGCCATCCAACCCTTGGATCAGCGATGACGTTGCT
  TTGTGGGACATAGAGATGAGCAAAGAGCCCAGCCAACAGCGAGTAAAAAGATGGGGCTTCTCTTTCGATG
  AGATATTGAAGGACCAGGTGGGGCGGGACCAGTTTCTACGATTCCTGGAGTCCGAATTCAGTTCAGAAAA
  CCTCAGGTTCTGGCTGGCTGTCCAAGATCTTAAGAAACAACCCCTACAGGATGTGGCCAAGAGGGTAGAA
  GAAATCTGGCAAGAGTTTCTGGCTCCAGGGGCTCCAAGTGCAATCAACCTGGATTCTCACAGCTATGAGA
  TAACCAGTCAAAATGTCAAAGATGGAGGGAGATATACATTTGAAGACGCCCAGGAGCACATCTACAAGCT
  GATGAAGAGTGACAGCTATGCCCGCTTCCTCCGGTCAAATGCTTACCAGGATTTGCTGCTGGCCAAGAAG
  AAGGGAAAGTCGCTGGCGGGCAAGCGCCTCACGGGCCTGATGCAGTCCTCCTGA
  
  
• Restriction Sites: SgfI-MluI
• ACCN: NM_001204423
• ORF Size: 1314 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_001204423.1, NP_001191352.1
• RefSeq Size: 5546
• RefSeq ORF: 1314
• Locus ID: 9628
• Protein Families: Druggable Genome
• Gene Summary: This gene encodes a member of the RGS (regulator of G protein signaling) family of proteins, which are defined by the presence of a RGS domain that confers the GTPase-activating activity of these proteins toward certain G alpha subunits. This protein also belongs to a subfamily of RGS proteins characterized by the presence of DEP and GGL domains, the latter a G beta 5-interacting domain. The RGS proteins negatively regulate G protein signaling, and may modulate neuronal, cardiovascular, lymphocytic activities, and cancer risk. Many alternatively spliced transcript variants encoding different isoforms with long or short N-terminal domains, complete or incomplete GGL domains, and distinct C-terminal domains, have been described for this gene, however, the full-length nature of some of these variants is not known. [provided by RefSeq, Mar 2011]
  Transcript Variant: This variant (9) differs in the 5' UTR, and is missing 2 non-consecutive exons compared to variant 1. This results in translation initiation from an in-frame downstream AUG, and an isoform (9) with a shorter N-terminus compared to isoform 1.