ASPM (NM_001206846) Human Untagged Clone

CAT#: SC331694

ASPM (untagged) - Homo sapiens asp (abnormal spindle) homolog, microcephaly associated (Drosophila) (ASPM), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: ASPM
• Synonyms: ASP; Calmbp1; MCPH5
• Vector: pCMV6 series
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_001206846, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGGCGAACCGGCGAGTGGGGCGAGGCTGCTGGGAAGTGAGCCCGACCGAGCGGAGGCCGCCCGCGGGGC
  TGCGGGGCCCCGCGGCCGAGGAGGAGGCGTCTTCCCCGCCGGTCCTGTCTCTCAGCCACTTCTGCAGGTC
  TCCTTTCCTTTGCTTCGGGGACGTTCTCCTGGGAGCCTCACGGACGCTGTCTCTGGCCCTAGACAACCCT
  AACGAGGAGGTGGCAGAAGTGAAGATCTCCCACTTCCCGGCCGCGGACCTGGGCTTCAGTGTGTCGCAGC
  GCTGTTTCGTGTTGCAGCCTAAAGAGAAAATTGTTATTTCTGTTAACTGGACACCACTCAAAGAAGGCCG
  AGTAAGAGAGATTATGACATTTCTTGTAAATGATGTTCTGAAACACCAAGCTATATTACTAGGAAATGCA
  GAAGAGCAGAAAAAGAAAAAGAGGAGTCTTTGGGATACCATTAAAAAGAAGAAAATTTCAGCCTCTACAA
  GTCACAACAGAAGGGTTTCAAATATTCAGAATGTTAATAAAACATTTAGTGTTTCCCAAAAAGTTGACAG
  AGTTAGGAGCCCACTACAAGCTTGTGAAAACTTGGCTATGAATGAAGGCGGTCCCCCAACAGAAAACAAT
  TCTTTAATACTTGAAGAAAATAAAATACCCATATCACCTATTAGCCCTGCTTTCAATGAATGCCATGGTG
  CAACTTGCTTGCCACTCTCTGTACGTCGATCTACTACCTACTCATCTCTTCATGCATCAGAAAATAGGGA
  ACTATTAAATGTACACAGTGCCAACGTTTCAAAAGTTTCTTTTAATGAGAAAGCTGTAACTGAAACTTCC
  TTTAATTCCGTAAATGTTAATGGCCAAAGAGGAGAGAATAGTAAACTTAGTCTTACCCCCAACTGTTCTT
  CAACTTTGAACATTACACAAAGCCAAATACATTTTCTAAGTCCAGATTCTTTTGTAAATAATAGTCATGG
  AGCTAATAATGAACTAGAATTAGTAACATGTCTTTCATCAGATATGTTTATGAAAGATAATTCACAGCCT
  GTGCATTTGGAATCAACAATTGCACATGAAATTTATCAGAAAATTTTAAGTCCAGATTCTTTCATAAAAG
  ATAATTATGGACTAAATCAGGATCTAGAATCAGAGTCAGTTAATCCTATTTTATCCCCTAATCAATTTTT
  AAAAGATAACATGGCATATATGTGTACATCTCAGCAAACATGTAAAGTACCATTATCAAATGAAAATTCT
  CAAGTCCCACAGTCTCCTGAAGATTGGAGAAAAAGTGAAGTTTCGCCACGTATTCCTGAATGTCAGGGTT
  CAAAATCTCCCAAAGCTATTTTTGAAGAACTAGTAGAAATGAAGTCAAATTACTACAGTTTTATAAAACA
  AAATAATCCTAAATTTTCTGCAGTTCAGGATATTTCTAGTCATAGCCACAATAAACAACCTAAGAGACGT
  CCAATACTTTCTGCCACTGTTACTAAAAGGAAGGCCACCTGTACCAGAGAAAACCAAACTGAGATTAATA
  AACCAAAAGCAAAAAGATGTCTCAACAGTGCAGTGGGTGAACATGAAAAAGTAATAAATAATCAAAAGGA
  AAAAGAAGATTTTCATTCTTATCTTCCAATTATAGATCCAATATTAAGTAAATCTAAGAGTTATAAAAAC
  GAGGTAACACCCTCTTCGACAACAGCTTCAGTTGCTCGGAAAAGAAAGAGCGATGGAAGCATGGAAGATG
  CAAATGTGAGAGTTGCAATTACAGAACATACAGAAGTGCGAGAAATCAAAAGAATCCATTTTTCTCCCTC
  AGAGCCTAAAACATCAGCTGTTAAGAAAACAAAAAATGTGACAACACCCATCTCAAAACGTATTAGCAAC
  AGAGAGAAATTAAACCTGAAGAAGAAAACTGATTTATCAATATTCAGAACTCCAATTTCTAAAACAAACA
  AAAGGACAAAACCCATTATCGCTGTGGCACAGTCCAGTTTGACCTTCATAAAACCATTAAAAACAGATAT
  TCCCAGACACCCGATGCCATTTGCTGCAAAAAACATGTTTTATGATGAACGCTGGAAGGAAAAGCAGGAA
  CAGGGCTTCACTTGGTGGTTAAATTTTATATTAACCCCTGATGACTTCACTGTAAAAACAAATATTTCTG
  AAGTAAATGCTGCTACTCTTCTTTTGGGAATAGAGAATCAACATAAAATAAGTGTTCCTAGAGCACCTAC
  AAAAGAGGAAATGTCTCTCAGAGCTTATACTGCTCGGTGTAGGTTAAACAGACTACGTCGTGCAGCATGC
  CGTTTGTTTACTTCTGAAAAAATGGTTAAAGCTATTAAAAAGCTTGAAATTGAAATTGAAGCTAGGCGGT
  TAATTGTTCGAAAAGATAGACACCTATGGAAAGATGTGGGAGAACGTCAGAAAGTCCTGAATTGGCTGTT
  GTCCTACAATCCTTTGTGGCTTCGAATTGGTCTAGAGACAACTTATGGAGAACTCATATCTTTGGAAGAT
  AACAGTGATGTCACAGGGTTGGCTATGTTTATTCTGAATCGCCTACTTTGGAATCCTGATATAGCAGCTG
  AGTATAGACACCCCACTGTTCCTCACCTGTATAGAGATGGTCATGAAGAAGCTTTGTCCAAGTTTACATT
  GAAAAAGTTATTGTTGTTGGTCTGTTTTCTTGATTATGCTAAAATTTCCAGACTCATTGATCATGATCCT
  TGTCTCTTCTGTAAAGATGCCGAATTCAAGGCTAGTAAAGAAATCCTTTTGGCTTTTTCACGAGATTTCC
  TAAGTGGTGAAGGTGACCTTTCCCGTCACCTTGGCTTATTGGGATTACCTGTTAACCATGTTCAGACACC
  ATTTGATGAATTTGATTTTGCCGTTACAAATCTTGCCGTAGACTTGCAATGTGGAGTGCGCCTTGTGCGA
  ACCATGGAACTTCTCACACAGAACTGGGACCTCTCAAAGAAACTCAGGATTCCGGCAATAAGTCGTCTTC
  AAAAGATGCACAATGTTGACATTGTTCTTCAAGTTCTTAAATCACGAGGAATTGAATTAAGTGATGAGCA
  TGGAAATACAATTCTATCTAAGGATATTGTGGATAGGCACAGAGAAAAAACTCTCAGGTTGCTTTGGAAA
  ATAGCGTTTGCTTTTCAGGTGGATATTTCCCTTAACTTAGATCAATTAAAGGAAGAAATTGCCTTTCTAA
  AACACACAAAGAGTATAAAGAAAACAATATCTCTACTATCATGCCATTCTGATGATCTTATTAATAAGAA
  AAAAGGCAAAAGGGATAGTGGTTCCTTTGAACAATATAGTGAAAACATAAAGTTATTGATGGATTGGGTA
  AATGCTGTTTGTGCCTTCTATAATAAAAAGGTGGAGAATTTTACAGTGTCTTTCTCAGACGGCCGTGTGT
  TATGTTACCTGATCCACCATTACCATCCTTGCTATGTGCCATTTGACGCTATATGTCAGCGTACTACTCA
  AACTGTGGAATGTACGCAAACTGGTTCAGTGGTATTAAATTCATCATCTGAATCTGATGACAGTTCTCTG
  GATATGTCTCTTAAAGCATTTGATCATGAAAATACTTCAGAGCTATACAAAGAGCTCCTAGAAAATGAAA
  AGAAAAATTTTCACTTGGTTAGGTCTGCAGTTAGAGACCTTGGTGGAATACCTGCTATGATTAATCATTC
  AGATATGTCAAATACAATTCCAGATGAAAAGGTGGTTATTACCTATTTGTCATTTCTTTGTGCAAGGCTT
  TTGGATCTTCGTAAAGAAATAAGAGCTGCTCGACTCATACAAACAACATGGAGAAAATATAAACTAAAAA
  CAGATCTCAAACGCCATCAGGAGAGAGAGAAAGCTGCAAGAATTATTCAATTGGCTGTAATCAATTTTCT
  AGCAAAACAAAGATTGAGAAAAAGAGTTAATGCAGCACTCGTCATTCAGAAATATTGGCGAAGAGTCTTA
  GCACAGAGAAAATTATTAATGTTAAAAAAGGAAAAGCTGGAAAAAGTTCAAAATAAAGCAGCATCACTTA
  TTCAGGCTATGTGGAGGAGATATAGAGCCAAGAAATATTTATGTAAAGTGAAAGCTGCCTGCAAGATTCA
  AGCCTGGTATAGATGTTGGAGAGCACACAAAGAATATCTAGCTATATTAAAAGCTGTTAAAATTATTCAA
  GGTTGCTTCTATACCAAACTAGAGAGAACACGGTTTTTGAATGTGAGAGCATCAGCAATTATCATTCAGA
  GAAAATGGAGAGCTATACTTCCTGCAAAGATAGCTCATGAACACTTCTTAATGATAAAAAGACATCGAGC
  TGCTTGTTTGATCCAAGCACATTATAGAGGATATAAAGGAAGGCAGGTCTTTCTTCGGCAGAAATCTGCT
  GCTTTGATCATACAAAAATATATACGAGCCAGGGAGGCTGGAAAGCATGAAAGGATAAAATATATTGAAT
  TTAAAAAATCTACAGTTATCCTACAAGCACTGGTGCGTGGTTGGCTAGTACGAAAAAGATTTTTAGAACA
  GAGAGCCAAAATTCGACTTCTTCACTTCACTGCAGCTGCATATTATCACCTGAATGCTGTTAGAATTCAA
  AGAGCCTATAAACTTTACCTGGCTGTGAAGAATGCTAACAAGCAGGTTAATTCAGTCATCTGTATTCAGA
  GATGGTTTCGAGCAAGATTACAAGAAAAGAGATTTATTCAGAAATATCATAGCATCAAAAAGATTGAGCA
  TGAAGGTCAAGAATGTCTGAGCCAGCGAAATAGGGCTGCATCAGTAATACAGAAAGCAGTGCGCCATTTT
  CTCCTCCGTAAAAAGCAGGAAAAATTCACTAGTGGAATCATTAAAATTCAGGCATTATGGAGAGGCTATT
  CTTGGAGGAAGAAAAATGATTGTACAAAAATTAAAGCTATACGACTAAGTCTTCAAGTTGTTAATAGGGA
  GATTCGAGAAGAAAACAAACTCTACAAAAGAACTGCACTTGCACTTCATTACCTTTTGACATATAAGCAC
  CTTTCTGCCATTCTTGAGGCCTTAAAACACCTAGAGGTAGTTACTAGATTGTCTCCACTTTGTTGTGAGA
  ACATGGCCCAGAGTGGAGCAATTTCTAAAATATTTGTTTTGATCCGAAGTTGTAATCGCAGTATTCCTTG
  TATGGAAGTCATCAGATATGCTGTGCAAGTCTTGCTTAATGTATCTAAGTATGAGAAAACTACTTCAGCA
  GTTTATGATGTAGAAAATTGTATAGATATACTATTGGAGCTTTTGCAGATATACCGAGAAAAGCCTGGTA
  ATAAAGTTGCAGACAAAGGCGGAAGCATTTTTACAAAAACTTGTTGTTTGTTGGCTATTTTACTGAAGAC
  AACAAATAGAGCCTCTGATGTACGAAGTAGGTCCAAAGTTGTTGACCGTATTTACAGTCTCTACAAACTT
  ACAGCTCATAAACATAAAATGAATACTGAAAGAATACTTTACAAGCAAAAGAAGAATTCTTCTATAAGCA
  TTCCTTTTATCCCAGAAACACCTGTAAGGACCAGAATAGTTTCAAGACTTAAGCCAGATTGGGTTTTGAG
  AAGAGATAACATGGAAGAAATCACAAATCCCCTGCAAGCTATTCAAATGGTGATGGATACGCTTGGCATT
  CCTTATTAG
  
  
• Restriction Sites: SgfI-MluI
• ACCN: NM_001206846
• ORF Size: 5679 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_001206846.1, NP_001193775.1
• RefSeq Size: 6151
• RefSeq ORF: 5679
• Locus ID: 259266
• Protein Families: Druggable Genome
• Gene Summary: This gene is the human ortholog of the Drosophila melanogaster 'abnormal spindle' gene (asp), which is essential for normal mitotic spindle function in embryonic neuroblasts. Studies in mouse also suggest a role of this gene in mitotic spindle regulation, with a preferential role in regulating neurogenesis. Mutations in this gene are associated with microcephaly primary type 5. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2011]
  Transcript Variant: This variant (2) lacks an in-frame exon in the coding region, compared to variant 1. This results in a shorter protein (isoform 2), compared to isoform 1.