Phospholipase D2 (PLD2) (NM_001243108) Human Untagged Clone

CAT#: SC331947

PLD2 (untagged) - Homo sapiens phospholipase D2 (PLD2), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: PLD2
• Synonyms: PLD1C
• Vector: pCMV6 series
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_001243108, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGACGGCGACCCCTGAGAGCCTCTTCCCCACTGGGGACGAACTGGACTCCAGCCAGCTCCAGATGGAGT
  CCGATGAGGTGGACACCCTGAAGGAGGGAGAGGACCCAGCCGACCGGATGCACCCGTTTCTGGCCATCTA
  TGAGCTTCAGTCTCTGAAAGTGCACCCCTTGGTGTTCGCACCTGGGGTCCCTGTCACAGCCCAGGTGGTG
  GGCACCGAAAGATATACCAGCGGATCCAAGGTGGGAACCTGCACTCTGTATTCTGTCCGCTTGACTCACG
  GCGACTTTTCCTGGACAACCAAGAAGAAATACCGTCATTTTCAGGAGCTGCATCGGGACCTCCTGAGACA
  CAAAGTCTTGATGAGTCTGCTCCCTCTGGCTCGATTTGCCGTTGCCTATTCTCCAGCCCGAGATGCAGGC
  AACAGAGAGATGCCCTCTCTACCCCGGGCAGGTCCTGAGGGCTCCACCAGACATGCAGCCAGCAAACAGA
  AATACCTGGAGAATTACCTCAACCGTCTCTTGACCATGTCTTTCTATCGCAACTACCATGCCATGACAGA
  GTTCCTGGAAGTCAGTCAGCTGTCCTTTATCCCGGACTTGGGCCGCAAAGGACTGGAGGGGATGATCCGG
  AAGCGCTCAGGTGGCCACCGTGTTCCTGGCCTCACCTGCTGTGGCCGAGACCAAGTTTGTTATCGCTGGT
  CCAAGAGGTGGCTGGTGGTGAAGGACTCCTTCCTGCTGTACATGTGCCTCGAGACAGGTGCCATCTCATT
  TGTTCAGCTCTTTGACCCTGGCTTTGAGGTGCAAGTGGGGAAAAGGAGCACGGAGGCACGGCACGGCGTG
  CGGATCGATACCTCCCACAGGTCCTTGATTCTCAAGTGCAGCAGCTACCGGCAGGCACGGTGGTGGGCCC
  AAGAGATCACTGAGCTGGCACAGGGCCCAGGCAGAGACTTCCTACAGCTGCACCGGCATGACAGCTACGC
  CCCACCCCGGCCTGGGACCTTGGCCCGGTGGTTTGTGAATGGGGCAGGTTACTTTGCTGCTGTGGCAGAT
  GCCATCCTTCGAGCTCAAGAGGAGATTTTCATCACAGACTGGTGGTTGAGTCCTGAGGTTTACCTGAAGC
  GTCCGGCCCATTCAGATGACTGGAGACTGGACATTATGCTCAAGAGGAAGGCGGAGGAGGGTGTCCGTGT
  GTCTATTCTGCTGTTTAAAGAAGTGGAATTGGCCTTGGGCATCAACAGTGGCTATAGCAAGAGGGCGCTG
  ATGCTGCTGCACCCCAACATAAAGGTGATGCGTCACCCAGACCAAGTGACGTTGTGGGCCCATCATGAGA
  AGCTCCTGGTGGTGGACCAAGTGGTAGCATTCCTGGGGGGACTGGACCTTGCCTATGGCCGCTGGGATGA
  CCTGCACTACCGACTGACTGACCTTGGAGACTCCTCTGAATCAGCTGCCTCCCAGCCTCCCACCCCGCGC
  CCAGACTCACCAGCCACCCCAGACCTCTCTCACAACCAATTCTTCTGGCTGGGCAAGGACTACAGCAATC
  TTATCACCAAGGACTGGGTGCAGCTGGACCGGCCTTTCGAAGATTTCATTGACAGGGAGACGACCCCTCG
  GATGCCATGGCGGGACGTTGGGGTGGTCGTCCATGGCCTACCGGCCCGGGACCTTGCCCGGCACTTCATC
  CAGCGCTGGAACTTCACCAAGACCACCAAGGCCAAGTACAAGACTCCCACATACCCCTACCTGCTTCCCA
  AGTCTACCAGCACGGCCAATCAGCTCCCCTTCACACTTCCAGGAGGGCAGTGCACCACCGTACAGGTCTT
  GCGATCAGTGGACCGCTGGTCAGCAGGGACTCTGGAGAACTCCATCCTCAATGCCTACCTGCACACCATC
  AGGGAGAGCCAGCACTTCCTCTACATTGAGAATCAGTTCTTCATTAGCTGCTCAGATGGGCGGACGGTTC
  TGAACAAGGTGGGCGATGAGATTGTGGACAGAATCCTGAAGGCCCACAAACAGGGGTGGTGTTACCGAGT
  CTACGTGCTTTTGCCCTTACTCCCTGGCTTCGAGGGTGACATCTCCACGGGCGGTGGCAACTCCATCCAG
  GCCATTCTGCACTTTACTTACAGGACCCTGTGTCGTGGGGAGTATTCAATCCTGCATCGCCTTAAAGCAG
  CCATGGGGACAGCATGGCGGGACTATATTTCCATCTGCGGGCTTCGTACACACGGAGAGCTGGGCGGGCA
  CCCCGTCTCGGAGCTCATCTACATCCACAGCAAGGTGCTCATCGCAGATGACCGGACAGTCATCATTGGT
  TCTGCAAACATCAATGACCGGAGCTTGCTGGGGAAGCGGGACAGTGAGCTGGCCGTGCTGATCGAGGACA
  CAGAGACGGAACCATCCCTCATGAATGGGGCAGAGTATCAGGCGGGCAGTGTGATTCTTGGAGCAAATAC
  CCGGCCAGACTTGGATCTCCGAGACCCCATCTGTGATGACTTCTTCCAGTTGTGGCAAGACATGGCTGAG
  AGCAACGCCAATATCTATGAGCAGATCTTCCGCTGCCTGCCATCCAATGCCACGCGTTCCCTGCGGACTC
  TCCGGGAGTACGTGGCCGTGGAGCCCTTGGCCACGGTCAGTCCCCCCTTGGCTCGGTCTGAGCTCACCCA
  GGTCCAGGGCCACCTGGTCCACTTCCCCCTCAAGTTCCTAGAGGATGAGTCTTTGCTGCCCCCGCTGGGT
  AGCAAGGAGGGCATGATCCCCCTAGAAGTGTGGACATAG
  
  
• Restriction Sites: SgfI-RsrII
• ACCN: NM_001243108
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_001243108.1, NP_001230037.1
• RefSeq Size: 3481 bp
• RefSeq ORF: 2769 bp
• Locus ID: 5338
• Cytogenetics: 17p13.2
• Protein Families: Druggable Genome
• Protein Pathways: Endocytosis, Ether lipid metabolism, Fc gamma R-mediated phagocytosis, Glycerophospholipid metabolism, GnRH signaling pathway, Metabolic pathways
• Gene Summary: 'The protein encoded by this gene catalyzes the hydrolysis of phosphatidylcholine to phosphatidic acid and choline. The activity of the encoded enzyme is enhanced by phosphatidylinositol 4,5-bisphosphate and ADP-ribosylation factor-1. This protein localizes to the peripheral membrane and may be involved in cytoskeletal organization, cell cycle control, transcriptional regulation, and/or regulated secretion. Two transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Jul 2011]'
  Transcript Variant: This variant (2) uses an alternate in-frame splice junction at the 3' end of an exon compared to variant 1. The resulting isoform (PLD2B) has the same N- and C-termini but is shorter compared to isoform PLD2A.