CACNA1B (NM_001243812) Human Untagged Clone

CAT#: SC332047

CACNA1B (untagged) - Homo sapiens calcium channel, voltage-dependent, N type, alpha 1B subunit (CACNA1B), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: CACNA1B
• Synonyms: BIII; CACNL1A5; CACNN; Cav2.2; DYT23
• Vector: pCMV6 series
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_001243812, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGGTCCGCTTCGGGGACGAGCTGGGCGGCCGCTATGGGGGCCCCGGCGGCGGAGAGCGGGCCCGGGGCG
  GCGGGGCCGGCGGGGCGGGGGGCCCGGGTCCCGGGGGGCTGCAGCCCGGCCAGCGGGTCCTCTACAAGCA
  ATCGATCGCGCAGCGCGCGCGGACCATGGCGCTGTACAACCCCATCCCGGTCAAGCAGAACTGCTTCACC
  GTCAACCGCTCGCTCTTCGTCTTCAGCGAGGACAACGTCGTCCGCAAATACGCGAAGCGCATCACCGAGT
  GGCCTCCATTCGAGTATATGATCCTGGCCACCATCATCGCCAACTGCATCGTGCTGGCCCTGGAGCAGCA
  CCTCCCTGATGGGGACAAAACGCCCATGTCCGAGCGGCTGGACGACACGGAGCCCTATTTCATCGGGATC
  TTTTGCTTCGAGGCAGGGATCAAAATCATCGCTCTGGGCTTTGTCTTCCACAAGGGCTCTTACCTGCGGA
  ACGGCTGGAACGTCATGGACTTCGTGGTCGTCCTCACAGGGATCCTTGCCACGGCTGGAACTGACTTCGA
  CCTGCGAACACTGAGGGCTGTGCGTGTGCTGAGGCCCCTGAAGCTGGTGTCTGGGATTCCAAGTTTGCAG
  GTGGTGCTCAAGTCCATCATGAAGGCCATGGTTCCACTCCTGCAGATTGGGCTGCTTCTCTTCTTTGCCA
  TCCTCATGTTTGCCATCATTGGCCTGGAGTTCTACATGGGCAAGTTCCACAAGGCCTGTTTCCCCAACAG
  CACAGATGCGGAGCCCGTGGGTGACTTCCCCTGTGGCAAGGAGGCCCCAGCCCGGCTGTGCGAGGGCGAC
  ACTGAGTGCCGGGAGTACTGGCCAGGACCCAACTTTGGCATCACCAACTTTGACAATATCCTGTTTGCCA
  TCTTGACGGTGTTCCAGTGCATCACCATGGAGGGCTGGACTGACATCCTCTATAATACAAACGATGCGGC
  CGGCAACACCTGGAACTGGCTCTACTTCATCCCTCTCATCATCATCGGCTCCTTCTTCATGCTCAACCTG
  GTGCTGGGCGTGCTCTCGGGGGAGTTTGCCAAGGAGCGAGAGAGGGTGGAGAACCGCCGCGCCTTCCTGA
  AGCTGCGCCGGCAGCAGCAGATCGAGCGAGAGCTCAACGGGTACCTGGAGTGGATCTTCAAGGCGGAGGA
  AGTCATGCTGGCCGAGGAGGACAGGAATGCAGAGGAGAAGTCCCCTTTGGACGTGCTGAAGAGAGCGGCC
  ACCAAGAAGAGCAGAAATGACCTGATCCACGCAGAGGAGGGAGAGGACCGGTTTGCAGATCTCTGTGCTG
  TTGGATCCCCCTTCGCCCGCGCCAGCCTCAAGAGCGGGAAGACAGAGAGCTCGTCATACTTCCGGAGGAA
  GGAGAAGATGTTCCGGTTTTTTATCCGGCGCATGGTGAAGGCTCAGAGCTTCTACTGGGTGGTGCTGTGC
  GTGGTGGCCCTGAACACACTGTGTGTGGCCATGGTGCATTACAACCAGCCGCGGCGGCTTACCACGACCC
  TGTATTTTGCAGAGTTTGTTTTCCTGGGTCTCTTCCTCACAGAGATGTCCCTGAAGATGTATGGCCTGGG
  GCCCAGAAGCTACTTCCGGTCCTCCTTCAACTGCTTCGACTTTGGGGTCATCGTGGGGAGCGTCTTTGAA
  GTGGTCTGGGCGGCCATCAAGCCGGGAAGCTCCTTTGGGATCAGTGTGCTGCGGGCCCTCCGCCTGCTGA
  GGATCTTCAAAGTCACGAAGTACTGGAGCTCCCTGCGGAACCTGGTGGTGTCCCTGCTGAACTCCATGAA
  GTCCATCATCAGCCTGCTCTTCTTGCTCTTCCTGTTCATTGTGGTCTTCGCCCTGCTGGGGATGCAGCTG
  TTTGGGGGACAGTTCAACTTCCAGGATGAGACTCCCACAACCAACTTCGACACCTTCCCTGCCGCCATCC
  TCACTGTCTTCCAGATCCTGACGGGAGAGGACTGGAATGCAGTGATGTATCACGGGATCGAATCGCAAGG
  CGGCGTCAGCAAAGGCATGTTCTCGTCCTTTTACTTCATTGTCCTGACACTGTTCGGAAACTACACTCTG
  CTGAATGTCTTTCTGGCCATCGCTGTGGACAACCTGGCCAACGCCCAAGAGCTGACCAAGGATGAAGAGG
  AGATGGAAGAAGCAGCCAATCAGAAGCTTGCTCTGCAAAAGGCCAAAGAAGTGGCTGAAGTCAGCCCCAT
  GTCTGCCGCGAACATCTCCATCGCCGCCAGGCAGCAGAACTCGGCCAAGGCGCGCTCGGTGTGGGAGCAG
  CGGGCCAGCCAGCTACGGCTGCAGAACCTGCGGGCCAGCTGCGAGGCGCTGTACAGCGAGATGGACCCCG
  AGGAGCGGCTGCGCTTCGCCACTACGCGCCACCTGCGGCCCGACATGAAGACGCACCTGGACCGGCCGCT
  GGTGGTGGAGCTGGGCCGCGACGGCGCGCGGGGGCCCGTGGGAGGCAAAGCCCGACCTGAGGCTGCGGAG
  GCCCCCGAGGGCGTCGACCCTCCGCGCAGGCACCACCGGCACCGCGACAAGGACAAGACCCCCGCGGCGG
  GGGACCAGGACCGAGCAGAGGCCCCGAAGGCGGAGAGCGGGGAGCCCGGTGCCCGGGAGGAGCGGCCGCG
  GCCGCACCGCAGCCACAGCAAGGAGGCCGCGGGGCCCCCGGAGGCGCGGAGCGAGCGCGGCCGAGGCCCA
  GGCCCCGAGGGCGGCCGGCGGCACCACCGGCGCGGCTCCCCGGAGGAGGCGGCCGAGCGGGAGCCCCGAC
  GCCACCGCGCGCACCGGCACCAGGATCCGAGCAAGGAGTGCGCCGGCGCCAAGGGCGAGCGGCGCGCGCG
  GCACCGCGGCGGCCCCCGAGCGGGGCCCCGGGAGGCGGAGAGCGGGGAGGAGCCGGCGCGGCGGCACCGG
  GCCCGGCACAAGGCGCAGCCTGCTCACGAGGCTGTGGAGAAGGAGACCACGGAGAAGGAGGCCACGGAGA
  AGGAGGCTGAGATAGTGGAAGCCGACAAGGAAAAGGAGCTCCGGAACCACCAGCCCCGGGAGCCACACTG
  TGACCTGGAGACCAGTGGGACTGTGACTGTGGGTCCCATGCACACACTGCCCAGCACCTGTCTCCAGAAG
  GTGGAGGAACAGCCAGAGGATGCAGACAATCAGCGGAACGTCACTCGCATGGGCAGTCAGCCCCCAGACC
  CGAACACTATTGTACATATCCCAGTGATGCTGACGGGCCCTCTTGGGGAAGCCACGGTCGTTCCCAGTGG
  TAACGTGGACCTGGAAAGCCAAGCAGAGGGGAAGAAGGAGGTGGAAGCGGATGACGTGATGAGGAGCGGC
  CCCCGGCCTATCGTCCCATACAGCTCCATGTTCTGTTTAAGCCCCACCAACCTGCTCCGCCGCTTCTGCC
  ACTACATCGTGACCATGAGGTACTTCGAGGTGGTCATTCTCGTGGTCATCGCCTTGAGCAGCATCGCCCT
  GGCTGCTGAGGACCCAGTGCGCACAGACTCGCCCAGGAACAACGCTCTGAAATACCTGGATTACATTTTC
  ACTGGTGTCTTTACCTTTGAGATGGTGATAAAGATGATCGACTTGGGACTGCTGCTTCACCCTGGAGCCT
  ATTTCCGGGACTTGTGGAACATTCTGGACTTCATTGTGGTCAGTGGCGCCCTGGTGGCGTTTGCTTTCTC
  AGGATCCAAAGGGAAAGACATCAATACCATCAAGTCTCTGAGAGTCCTTCGTGTCCTGCGGCCCCTCAAG
  ACCATCAAACGGCTGCCCAAGCTCAAGGCTGTGTTTGACTGTGTGGTGAACTCCCTGAAGAATGTCCTCA
  ACATCTTGATTGTCTACATGCTCTTCATGTTCATATTTGCCGTCATTGCGGTGCAGCTCTTCAAAGGGAA
  GTTTTTCTACTGCACAGATGAATCCAAGGAGCTGGAGAGGGACTGCAGGGGTCAGTATTTGGATTATGAG
  AAGGAGGAAGTGGAAGCTCAGCCCAGGCAGTGGAAGAAATACGACTTTCACTACGACAATGTGCTCTGGG
  CTCTGCTGACGCTGTTCACAGTGTCCACGGGAGAAGGCTGGCCCATGGTGCTGAAACACTCCGTGGATGC
  CACCTATGAGGAGCAGGGTCCAAGCCCTGGGTACCGCATGGAGCTGTCCATCTTCTACGTGGTCTACTTT
  GTGGTCTTTCCCTTCTTCTTCGTCAACATCTTTGTGGCTTTGATCATCATCACCTTCCAGGAGCAGGGGG
  ACAAGGTGATGTCTGAATGCAGCCTGGAGAAGAACGAGAGGGCTTGCATTGACTTCGCCATCAGCGCCAA
  ACCCCTGACACGGTACATGCCCCAAAACCGGCAGTCGTTCCAGTATAAGACGTGGACATTTGTGGTCTCC
  CCGCCCTTTGAATACTTCATCATGGCCATGATAGCCCTCAACACTGTGGTGCTGATGATGAAGTTCTATG
  ATGCACCCTATGAGTACGAGCTGATGCTGAAATGCCTGAACATCGTGTTCACATCCATGTTCTCCATGGA
  ATGCGTGCTGAAGATCATCGCCTTTGGGGTGCTGAACTATTTCAGAGATGCCTGGAATGTCTTTGACTTT
  GTCACTGTGTTGGGAAGTATTACTGATATTTTAGTAACAGAGATTGCGGAAACGAACAATTTCATCAACC
  TCAGCTTCCTCCGCCTCTTTCGAGCTGCGCGGCTGATCAAGCTGCTCCGCCAGGGCTACACCATCCGCAT
  CCTGCTGTGGACCTTTGTCCAGTCCTTCAAGGCCCTGCCCTACGTGTGTCTGCTCATTGCCATGCTGTTC
  TTCATCTACGCCATCATCGGCATGCAGGTGTTTGGGAATATTGCCCTGGATGATGACACCAGCATCAACC
  GCCACAACAACTTCCGGACGTTTTTGCAAGCCCTGATGCTGCTGTTCAGGAGCGCCACGGGGGAGGCCTG
  GCACGAGATCATGCTGTCCTGCCTGAGCAACCAGGCCTGTGATGAGCAGGCCAATGCCACCGAGTGTGGA
  AGTGACTTTGCCTACTTCTACTTCGTCTCCTTCATCTTCCTGTGCTCCTTTCTGATGTTGAACCTCTTTG
  TGGCTGTGATCATGGACAATTTTGAGTACCTCACGCGGGACTCTTCCATCCTAGGTCCTCACCACTTGGA
  TGAGTTCATCCGGGTCTGGGCTGAATACGACCCGGCTGCGTGTGGGCGCATCAGTTACAATGACATGTTT
  GAGATGCTGAAACACATGTCCCCGCCTCTGGGGCTGGGGAAGAAATGCCCTGCTCGAGTTGCTTACAAGC
  GCCTGGTTCGCATGAACATGCCCATCTCCAACGAGGACATGACTGTTCACTTCACGTCCACGCTGATGGC
  CCTCATCCGGACGGCACTGGAGATCAAGCTGGCCCCAGCTGGGACAAAGCAGCATCAGTGTGACGCGGAG
  TTGAGGAAGGAGATTTCCGTTGTGTGGGCCAATCTGCCCCAGAAGACTTTGGACTTGCTGGTACCACCCC
  ATAAGCCTGATGAGATGACAGTGGGGAAGGTTTATGCAGCTCTGATGATATTCGACTTCTACAAGCAGAA
  CAAAACCACCAGAGACCAGATGCAGCAGGCTCCTGGAGGCCTCTCCCAGATGGGTCCTGTGTCCCTGTTC
  CACCCTCTGAAGGCCACCCTGGAGCAGACACAGCCGGCTGTGCTCCGAGGAGCCCGGGTTTTCCTTCGAC
  AGAAGAGTTCCACCTCCCTCAGCAATGGCGGGGCCATACAAAACCAAGAGAGTGGCATCAAAGAGTCTGT
  CTCCTGGGGCACTCAAAGGACCCAGGATGCACCCCATGAGGCCAGGCCACCCCTGGAGCGTGGCCACTCC
  ACAGAGATCCCTGTGGGGCGGTCAGGAGCACTGGCTGTGGACGTTCAGATGCAGAGCATAACCCGGAGGG
  GCCCTGATGGGGAGCCCCAGCCTGGGCTGGAGAGCCAGGGTCGAGCGGCCTCCATGCCCCGCCTTGCGGC
  CGAGACTCAGCCCGTCACAGATGCCAGCCCCATGAAGCGCTCCATCTCCACGCTGGCCCAGCGGCCCCGT
  GGGACTCATCTTTGCAGCACCACCCCGGACCGCCCACCCCCTAGCCAGGCGTCGTCGCACCACCACCACC
  ACCGCTGCCACCGCCGCAGGGACAGGAAGCAGAGGTCCCTGGAGAAGGGGCCCAGCCTGTCTGCCGATAT
  GGATGGCGCACCAAGCAGTGCTGTGGGGCCGGGGCTGCCCCCGGGAGAGGGGCCTACAGGCTGCCGGCGG
  GAACGAGAGCGCCGGCAGGAGCGGGGCCGGTCCCAGGAGCGGAGGCAGCCCTCATCCTCCTCCTCGGAGA
  AGCAGCGCTTCTACTCCTGCGACCGCTTTGGGGGCCGTGAGCCCCCGAAGCCCAAGCCCTCCCTCAGCAG
  CCACCCAACGTCGCCAACAGCTGGCCAGGAGCCGGGACCCCACCCACAGGCCGGCTCAGCCGTGGGCTTT
  CCGAACACAACGCCCTGCTGCAGAGAGACCCCCTCAGCCAGCCCCTGGCCCCTGGCTCTCGAATTGGCTC
  TGACCCTTACCTGGGGCAGCGTCTGGACAGTGAGGCCTCTGTCCACGCCCTGCCTGAGGACACTCTCACT
  TTCGAGGAGGCTGTGGCCACCAACTCGGGCCGCTCCTCCAGGACTTCCTACGTGTCCTCCCTGA
  
  
• Restriction Sites: SgfI-MluI
• ACCN: NM_001243812
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_001243812.1, NP_001230741.1
• RefSeq Size: 9618 bp
• RefSeq ORF: 6714 bp
• Locus ID: 774
• Cytogenetics: 9q34.3
• Protein Families: Druggable Genome, Ion Channels: Calcium, Transmembrane
• Protein Pathways: Calcium signaling pathway, MAPK signaling pathway, Taste transduction, Type II diabetes mellitus
• Gene Summary: 'The protein encoded by this gene is the pore-forming subunit of an N-type voltage-dependent calcium channel, which controls neurotransmitter release from neurons. The encoded protein forms a complex with alpha-2, beta, and delta subunits to form the high-voltage activated channel. This channel is sensitive to omega-conotoxin-GVIA and omega-agatoxin-IIIA but insensitive to dihydropyridines. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2011]'
  Transcript Variant: This variant (2) uses an alternate splice junction at the 5' end of an exon compared to variant 1. The resulting isoform (2) has a shorter and distinct C-terminus compared to isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.