THBS3 (NM_001252607) Human Untagged Clone

CAT#: SC332199

THBS3 (untagged) - Homo sapiens thrombospondin 3 (THBS3), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: THBS3
• Synonyms: TSP3
• Vector: pCMV6 series
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_001252607, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGGAGACGCAGGAACTTCGGGGGGCCCTGGCTCTTCTCCTCCTTTGCTTTTTCACATCTGCCAGTCAGG
  ATCTGCAGGTAATTGACCTGCTGACTGTGGGCGAGTCTCGGCAGATGGTAGCTGTGGCAGAGAAGATCCG
  GACAGCCTTGCTCACTGCTGGGGACATCTACCTCTTATCCACCTTCCGCCTGCCCCCCAAGCAGGGTGGT
  GTCCTCTTTGGCCTCTATTCTCGCCAAGACAACACTCGATGGCTGGAGGCCTCTGTTGTAGGCAAGATCA
  ACAAAGTACTGGTGCGATACCAGCGGGAGGATGGCAAAGTCCACGCCGTGAACCTACAGCAAGCGGGCCT
  GGCTGATGGGCGCACACACACAGTTCTCCTGCGACTCCGAGGTCCCTCCAGACCCAGCCCTGCCCTACAT
  CTCTACGTGGACTGCAAACTGGGTGACCAACATGCAGGCCTTCCAGCACTGGCCCCCATTCCTCCAGCGG
  AGGTCGATGGGCTGGAGATTAGGACTGGACAGAAGGCGTATTTGAGGATGCAGGGCTTTGTGGAATCTAT
  GAAAATTATTCTGGGTGGGTCCATGGCCCGGGTAGGAGCCCTGAGTGAGTGTCCATTCCAAGGGGACGAG
  TCCATCCACAGTGCAGGGGAGCAGACCAAGGCGCTGGTCACCCAACTCACCCTCTTCAACCAGATCCTGG
  TGGAGCTGCGGGATGATATACGAGACCAGGTGAAGGAAATGTCCCTGATCCGAAACACCATTATGGAGTG
  TCAGGTGTGCGGCTTCCATGAGCAGCGTTCCCACTGCAGCCCCAATCCCTGCTTCCGAGGTGTGGACTGC
  ATGGAAGTGTACGAGTACCCAGGCTACCGCTGTGGGCCCTGCCCCCCTGGCCTGCAGGGCAACGGCACCC
  ACTGCAGTGACATCAATGAGTGTGCTCACGCTGACCCCTGTTTCCCGGGCTCCAGCTGCATCAACACCAT
  GCCCGGCTTCCACTGTGAGGCCTGTCCTCGAGGGTACAAGGGCACACAGGTGTCTGGTGTGGGCATTGAC
  TATGCCCGGGCCAGCAAACAGGTCTGCAATGACATCGATGAATGCAACGATGGCAACAATGGTGGCTGTG
  ACCCAAACTCCATCTGCACCAACACTGTGGGCTCTTTCAAGTGTGGTCCCTGCCGCCTGGGTTTCCTGGG
  CAACCAGAGCCAGGGCTGCCTCCCAGCCCGGACCTGCCACAGCCCAGCCCACAGCCCCTGCCACATCCAT
  GCTCACTGTCTCTTTGAACGCAATGGTGCAGTGTCCTGCCAGTGTAACGTGGGCTGGGCTGGGAATGGGA
  ACGTGTGTGGGACTGACACAGACATCGATGGCTACCCAGACCAAGCACTGCCCTGCATGGACAACAACAA
  ACACTGCAAACAGGACAACTGCCTTTTGACACCCAACTCTGGGCAGGAAGATGCTGATAATGATGGTGTG
  GGGGACCAGTGTGATGATGATGCTGATGGGGATGGGATCAAGAATGTTGAGGACAACTGCCGGCTGTTCC
  CCAACAAAGACCAGCAGAACTCAGATACAGATTCATTTGGTGATGCCTGTGACAATTGCCCCAACGTTCC
  CAACAATGACCAGAAGGACACAGATGGCAATGGGGAAGGAGATGCCTGTGACAACGACGTGGATGGGGAT
  GGCATCCCCAATGGATTGGACAATTGCCCTAAAGTCCCCAACCCACTACAGACAGACAGGGATGAGGACG
  GGGTGGGAGATGCTTGCGACAGCTGCCCTGAAATGAGCAATCCTACCCAGACAGATGCAGACAGCGACCT
  GGTGGGGGATGTCTGTGATACTAATGAAGACAGCGATGGGGATGGGCATCAGGACACCAAGGACAACTGC
  CCACAGCTGCCAAATAGCTCCCAGCTGGACTCTGATAACGATGGACTTGGAGATGAGTGTGATGGGGATG
  ATGACAATGATGGCATCCCAGATTATGTGCCTCCTGGTCCCGATAACTGCCGCCTGGTACCCAATCCCAA
  TCAGAAGGACTCAGATGGCAATGGCGTTGGTGATGTGTGTGAGGATGACTTTGACAATGATGCTGTGGTC
  GACCCCCTGGATGTGTGTCCTGAAAGTGCAGAGGTAACGCTTACGGATTTTCGGGCCTATCAGACCGTCG
  TCCTGGATCCTGAGGGTGATGCTCAGATTGACCCAAACTGGGTTGTGCTCAACCAGGGCATGGAAATCGT
  TCAGACCATGAACAGTGACCCTGGCTTGGCAGTTGGATACACGGCCTTCAATGGTGTGGACTTTGAAGGC
  ACCTTCCATGTGAACACAGTGACTGATGATGACTACGCAGGCTTTCTCTTCAGTTATCAAGACAGTGGCC
  GCTTCTACGTAGTCATGTGGAAGCAGACCGAGCAGACCTACTGGCAGGCTACACCCTTCCGGGCGGTTGC
  CCAGCCCGGGCTGCAGCTCAAGGCAGTGACATCAGTGTCTGGCCCAGGTGAGCACCTCCGAAATGCCCTG
  TGGCATACTGGCCACACCCCTGATCAGGTACGACTGCTGTGGACAGACCCACGAAATGTGGGCTGGCGGG
  ACAAGACCTCCTATCGCTGGCAGCTTCTGCACCGGCCTCAAGTTGGCTACATTCGGGTGAAGCTCTATGA
  GGGACCCCAGCTTGTGGCGGATTCTGGGGTGATCATTGACACATCCATGCGAGGGGGGCGTCTTGGTGTA
  TTCTGCTTCTCCCAAGAAAACATAATTTGGTCCAATCTCCAGTATCGATGCAATGACACAGTGCCTGAGG
  ACTTTGAGCCATTCCGGAGGCAGCTGCTCCAGGGAAGGGTGTGA
  
  
• Restriction Sites: SgfI-MluI
• ACCN: NM_001252607
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_001252607.1, NP_001239536.1
• RefSeq Size: 3224 bp
• RefSeq ORF: 2844 bp
• Locus ID: 7059
• Cytogenetics: 1q22
• Protein Families: Druggable Genome
• Protein Pathways: ECM-receptor interaction, Focal adhesion, TGF-beta signaling pathway
• Gene Summary: 'The protein encoded by this gene belongs to the thrombospondin family. Thrombospondin family members are adhesive glycoproteins that mediate cell-to-cell and cell-to-matrix interactions. This protein forms a pentameric molecule linked by a single disulfide bond. This gene shares a common promoter with metaxin 1. Alternate splicing results in coding and non-coding transcript variants. [provided by RefSeq, Nov 2011]'
  Transcript Variant: This variant (2) lacks an in-frame exon in the coding region, compared to variant 1. The encoded isoform (2) is shorter, compared to isoform 1.