SGLT1 (SLC5A1) (NM_001256314) Human Untagged Clone

CAT#: SC332345

SLC5A1 (untagged) - Homo sapiens solute carrier family 5 (sodium/glucose cotransporter), member 1 (SLC5A1), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: SLC5A1
• Synonyms: D22S675; NAGT; SGLT1
• Vector: pCMV6 series
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_001256314, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGCCAGAGTACCTGAGGAAGCGGTTTGGAGGCCAGCGGATCCAGGTCTACCTTTCCCTTCTGTCCCTGC
  TGCTCTACATTTTCACCAAGATCTCGGCAGACATCTTCTCGGGGGCCATATTCATCAATCTGGCCTTAGG
  CCTGAATCTGTATTTAGCCATCTTTCTCTTATTGGCAATCACTGCCCTTTACACAATTACAGGGGGCCTG
  GCGGCGGTGATTTACACGGACACCTTGCAGACGGTGATCATGCTGGTGGGGTCTTTAATCCTGACTGGGT
  TTGCTTTTCACGAAGTGGGAGGCTATGACGCCTTCATGGAAAAGTACATGAAAGCCATTCCAACCATAGT
  GTCTGATGGCAACACCACCTTTCAGGAAAAATGCTACACTCCAAGGGCCGACTCCTTCCACATCTTCCGA
  GATCCCCTCACGGGAGACCTCCCATGGCCTGGGTTCATCTTTGGGATGTCCATCCTTACCTTGTGGTACT
  GGTGCACAGATCAGGTCATTGTGCAGCGCTGCCTCTCAGCCAAGAATATGTCTCACGTGAAGGGTGGCTG
  CATCCTGTGTGGGTATCTAAAGCTGATGCCCATGTTCATCATGGTGATGCCAGGAATGATCAGCCGCATT
  CTGTACACAGAAAAAATTGCCTGTGTCGTCCCTTCAGAATGTGAGAAATATTGCGGTACCAAGGTTGGCT
  GTACCAACATCGCCTATCCAACCTTAGTGGTGGAGCTCATGCCCAATGGACTGCGAGGCCTGATGCTATC
  AGTCATGCTGGCCTCCCTCATGAGCTCCCTGACCTCCATCTTCAACAGCGCCAGCACCCTCTTCACCATG
  GACATCTACGCCAAGGTCCGCAAGAGAGCATCTGAGAAAGAGCTCATGATTGCCGGAAGGTTGTTTATCC
  TGGTGCTGATTGGCATCAGCATCGCCTGGGTGCCCATTGTGCAGTCAGCACAAAGTGGGCAACTCTTCGA
  TTACATCCAGTCCATCACCAGTTACTTGGGACCACCCATTGCGGCTGTCTTCCTGCTTGCTATTTTCTGG
  AAGAGAGTCAATGAGCCAGGAGCCTTTTGGGGACTGATCCTAGGACTTCTGATTGGGATTTCACGTATGA
  TTACTGAGTTTGCTTATGGAACCGGGAGCTGCATGGAGCCCAGCAACTGTCCCACGATTATCTGTGGGGT
  GCACTACTTGTACTTTGCCATTATCCTCTTCGCCATTTCTTTCATCACCATCGTGGTCATCTCCCTCCTC
  ACCAAACCCATTCCGGATGTGCATCTCTACCGTCTGTGTTGGAGCCTGCGCAACAGCAAAGAGGAGCGTA
  TTGACCTGGATGCGGAAGAGGAGAACATCCAAGAAGGCCCTAAGGAGACCATTGAAATAGAAACACAAGT
  TCCTGAGAAGAAAAAAGGAATCTTCAGGAGAGCCTATGACCTATTTTGTGGGCTAGAGCAGCACGGTGCA
  CCCAAGATGACTGAGGAAGAGGAGAAAGCCATGAAGATGAAGATGACGGACACCTCTGAGAAGCCTTTGT
  GGAGGACAGTGTTGAACGTCAATGGCATCATCCTGGTGACCGTGGCTGTCTTTTGCCATGCATATTTTGC
  CTGA
  
  
• Restriction Sites: SgfI-MluI
• ACCN: NM_001256314
• ORF Size: 1614 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_001256314.1, NP_001243243.1
• RefSeq Size: 4779
• RefSeq ORF: 1614
• Locus ID: 6523
• Protein Families: Druggable Genome, Transmembrane
• Gene Summary: This gene encodes a member of the sodium-dependent glucose transporter (SGLT) family. The encoded integral membrane protein is the primary mediator of dietary glucose and galactose uptake from the intestinal lumen. Mutations in this gene have been associated with glucose-galactose malabsorption. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012]
  Transcript Variant: This variant (2) lacks several 5' exons compared to variant 1. This variant represents translation initiation at a downstream AUG compared to variant 1; the 5'-most initiation codon, as used in variant 1, is associated with a weak Kozak sequence and a truncated ORF that would render the transcript a candidate for nonsense-mediated decay (NMD). Leaky scanning may allow translation initiation at the downstream AUG. The encoded protein (isoform 2) has a shorter N-terminus, compared to isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.