CLCN4 (NM_001256944) Human Untagged Clone

CAT#: SC332498

CLCN4 (untagged) - Homo sapiens chloride channel, voltage-sensitive 4 (CLCN4), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: CLCN4
• Synonyms: ClC-4; ClC-4A; CLC4; MRX15; MRX49; MRXSRC
• Vector: pCMV6 series
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_001256944, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGACGGACCTGAAGGAGGGGGTCTGCCTGTCTGCCTTCTGGTATAGCCATGAGCAGTGTTGCTGGACTT
  CTAACGAGACCACTTTTGAGGACAGAGACAAGTGTCCCCTGTGGCAGAAATGGTCGGAGCTGCTGGTGAA
  TCAGTCAGAGGGTGCCAGTGCTTACATTCTGAATTACTTAATGTACATCCTATGGGCGCTGCTGTTTGCA
  TTTTTGGCTGTCTCCCTGGTGCGTGTATTTGCACCATATGCCTGTGGCTCTGGCATACCAGAGATAAAGA
  CCATTTTGAGCGGCTTTATCATCAGGGGCTACTTGGGGAAGTGGACCCTGCTAATCAAGACAGTCACGCT
  GGTGCTGGTAGTGTCCTCCGGTCTGAGCCTTGGGAAGGAAGGGCCGCTAGTGCACGTGGCTTGTTGCTGT
  GGCAACTTCTTCAGCAGCCTTTTCTCCAAGTACAGCAAGAATGAGGGCAAGAGGCGGGAGGTGCTTTCAG
  CTGCAGCGGCTGCTGGAGTCTCTGTTGCCTTTGGTGCACCAATTGGAGGCGTGCTTTTCAGTCTAGAAGA
  GGTCAGTTACTACTTTCCCCTGAAGACCTTGTGGAGGTCATTTTTCGCAGCCCTGGTGGCGGCCTTTACG
  CTGAGATCCATCAATCCCTTTGGGAATAGCCGTCTCGTTCTCTTTTATGTGGAATACCACACGCCCTGGT
  ACATGGCTGAACTCTTCCCCTTCATCCTGCTTGGGGTCTTCGGGGGCTTGTGGGGAACCCTCTTCATCCG
  CTGCAACATCGCCTGGTGCAGGAGGCGCAAGACCACCAGGCTGGGGAAGTACCCGGTGCTGGAGGTCATT
  GTGGTGACTGCCATCACTGCCATCATTGCCTACCCCAATCCCTACACACGCCAGAGCACCAGCGAGCTCA
  TTTCTGAGCTGTTCAATGACTGTGGAGCCCTTGAGTCTTCCCAGCTCTGTGACTACATCAATGACCCCAA
  CATGACTCGGCCTGTGGATGACATTCCAGACCGGCCGGCTGGTGTCGGTGTTTACACGGCCATGTGGCAG
  CTGGCCCTGGCACTGATCTTCAAAATCGTCGTTACCATATTTACCTTTGGCATGAAGATCCCGTCGGGCC
  TCTTCATCCCCAGCATGGCTGTGGGCGCGATAGCGGGCAGGATGGTGGGAATTGGCGTGGAGCAGCTGGC
  CTACCATCACCATGACTGGATCATCTTCAGGAACTGGTGCAGACCCGGTGCAGACTGTGTCACGCCAGGG
  CTGTACGCAATGGTGGGAGCTGCGGCCTGCCTCGGTGGAGTTACCAGGATGACGGTGTCATTGGTGGTCA
  TCATGTTTGAATTAACCGGGGGTCTGGAGTACATCGTGCCCCTGATGGCGGCGGCTGTGACCAGCAAGTG
  GGTAGCTGATGCATTTGGGAAAGAAGGCATCTACGAGGCCCACATCCACTTAAATGGGTACCCTTTCCTT
  GACGTGAAGGACGAGTTTACTCACCGCACACTGGCCACCGACGTCATGCGGCCCCGGCGGGGAGAGCCGC
  CACTGTCGGTGCTCACCCAGGACAGCATGACTGTCGAGGACGTGGAGACGCTCATCAAGGAGACCGACTA
  CAACGGCTTCCCCGTGGTGGTCTCCAGAGACTCCGAGCGCCTCATTGGATTTGCCCAGAGGAGGGAACTG
  ATTCTCGCAATAAAGAACGCCAGACAGAGGCAGGAGGGCATTGTGAGCAATTCCATCATGTACTTCACGG
  AGGAACCCCCCGAGCTGCCGGCCAACAGCCCACATCCCCTGAAGCTGCGGCGCATCCTGAACCTCAGCCC
  GTTTACAGTGACAGACCACACTCCGATGGAAACGGTGGTGGATATCTTCCGGAAACTGGGGCTTCGGCAG
  TGCCTGGTGACGCGGAGCGGGAGACTTCTTGGCATCATCACAAAAAAGGATGTTCTGAGACATATGGCCC
  AGATGGCAAACCAGGACCCCGAATCCATCATGTTTAATTAG
  
  
• Restriction Sites: SgfI-MluI
• ACCN: NM_001256944
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_001256944.1, NP_001243873.1
• RefSeq Size: 6534 bp
• RefSeq ORF: 2001 bp
• Locus ID: 1183
• Cytogenetics: Xp22.2
• Protein Families: Druggable Genome, Ion Channels: Other, Transmembrane
• Gene Summary: 'The CLCN family of voltage-dependent chloride channel genes comprises nine members (CLCN1-7, Ka and Kb) which demonstrate quite diverse functional characteristics while sharing significant sequence homology. Chloride channel 4 has an evolutionary conserved CpG island and is conserved in both mouse and hamster. This gene is mapped in close proximity to APXL (Apical protein Xenopus laevis-like) and OA1 (Ocular albinism type I), which are both located on the human X chromosome at band p22.3. The physiological role of chloride channel 4 remains unknown but may contribute to the pathogenesis of neuronal disorders. Alternate splicing results in two transcript variants that encode different proteins. [provided by RefSeq, Mar 2012]'
  Transcript Variant: This variant (2) differs in the 5' UTR and lacks an in-frame portion of the 5' coding region, compared to variant 1. The resulting isoform (2) has a shorter N-terminus, compared to isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.