NFAT1 (NFATC2) (NM_001258294) Human Untagged Clone

CAT#: SC332640

NFATC2 (untagged) - Homo sapiens nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 (NFATC2), transcript variant 5

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: NFATC2
• Synonyms: NFAT1; NFATP
• Vector: pCMV6 series
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_001258294, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGTCACCTCGAACCAGCCTCGCCGAGGACAGCTGCCTGGGCCGCCACTCGCCCGTGCCCCGTCCGGCCT
  CCCGCTCCTCATCGCCTGGTGCCAAGCGGAGGCATTCGTGCGCCGAGGCCTTGGTTGCCCTGCCGCCCGG
  AGCCTCACCCCAGCGCTCCCGGAGCCCCTCGCCGCAGCCCTCATCTCACGTGGCACCCCAGGACCACGGC
  TCCCCGGCTGGGTACCCCCCTGTGGCTGGCTCTGCCGTGATCATGGATGCCCTGAACAGCCTCGCCACGG
  ACTCGCCTTGTGGGATCCCCCCCAAGATGTGGAAGACCAGCCCTGACCCCTCGCCGGTGTCTGCCGCCCC
  ATCCAAGGCCGGCCTGCCTCGCCACATCTACCCGGCCGTGGAGTTCCTGGGGCCCTGCGAGCAGGGCGAG
  AGGAGAAACTCGGCTCCAGAATCCATCCTGCTGGTTCCGCCCACTTGGCCCAAGCCGCTGGTGCCTGCCA
  TTCCCATCTGCAGCATCCCAGTGACTGCATCCCTCCCTCCACTTGAGTGGCCGCTGTCCAGTCAGTCAGG
  CTCTTACGAGCTGCGGATCGAGGTGCAGCCCAAGCCACATCACCGGGCCCACTATGAGACAGAAGGCAGC
  CGAGGGGCTGTCAAAGCTCCAACTGGAGGCCACCCTGTGGTTCAGCTCCATGGCTACATGGAAAACAAGC
  CTCTGGGACTTCAGATCTTCATTGGGACAGCTGATGAGCGGATCCTTAAGCCGCACGCCTTCTACCAGGT
  GCACCGAATCACGGGGAAAACTGTCACCACCACCAGCTATGAGAAGATAGTGGGCAACACCAAAGTCCTG
  GAGATACCCTTGGAGCCCAAAAACAACATGAGGGCAACCATCGACTGTGCGGGGATCTTGAAGCTTAGAA
  ACGCCGACATTGAGCTGCGGAAAGGCGAGACGGACATTGGAAGAAAGAACACGCGGGTGAGACTGGTTTT
  CCGAGTTCACATCCCAGAGTCCAGTGGCAGAATCGTCTCTTTACAGACTGCATCTAACCCCATCGAGTGC
  TCCCAGCGATCTGCTCACGAGCTGCCCATGGTTGAAAGACAAGACACAGACAGCTGCCTGGTCTATGGCG
  GCCAGCAAATGATCCTCACGGGGCAGAACTTTACATCCGAGTCCAAAGTTGTGTTTACTGAGAAGACCAC
  AGATGGACAGCAAATTTGGGAGATGGAAGCCACGGTGGATAAGGACAAGAGCCAGCCCAACATGCTTTTT
  GTTGAGATCCCTGAATATCGGAACAAGCATATCCGCACACCTGTAAAAGTGAACTTCTACGTCATCAATG
  GGAAGAGAAAACGAAGTCAGCCTCAGCACTTTACCTACCACCCAGTCCCAGCCATCAAGACGGAGCCCAC
  GGATGAATATGACCCCACTCTGATCTGCAGCCCCACCCATGGAGGCCTGGGGAGCCAGCCTTACTACCCC
  CAGCACCCGATGGTGGCCGAGTCCCCCTCCTGCCTCGTGGCCACCATGGCTCCCTGCCAGCAGTTCCGCA
  CGGGGCTCTCATCCCCTGACGCCCGCTACCAGCAACAGAACCCAGCGGCCGTACTCTACCAGCGGAGCAA
  GAGCCTGAGCCCCAGCCTGCTGGGCTATCAGCAGCCGGCCCTCATGGCCGCCCCGCTGTCCCTTGCGGAC
  GCTCACCGCTCTGTGCTGGTGCACGCCGGCTCCCAGGGCCAGAGCTCAGCCCTGCTCCACCCCTCTCCGA
  CCAACCAGCAGGCCTCGCCTGTGATCCACTACTCACCCACCAACCAGCAGCTGCGCTGCGGAAGCCACCA
  GGAGTTCCAGCACATCATGTACTGCGAGAATTTCGCACCAGGCACCACCAGACCTGGCCCGCCCCCGGTC
  AGTCAAGGTCAGAGGCTGAGCCCGGGTTCCTACCCCACAGTCATTCAGCAGCAGAATGCCACGAGCCAAA
  GAGCCGCCAAAAACGGACCCCCGGTCAGTGACCAAAAGGAAGTATTACCTGCGGGGGTGACCATTAAACA
  GGAGCAGAACTTGGACCAGACCTACTTGGATGATGAGCTGATAGACACACACCTTAGCTGGATACAAAAC
  ATATTATGA
  
  
• Restriction Sites: SgfI-MluI
• ACCN: NM_001258294
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_001258294.1, NP_001245223.1
• RefSeq Size: 6938 bp
• RefSeq ORF: 2109 bp
• Locus ID: 4773
• Cytogenetics: 20q13.2
• Protein Families: Druggable Genome, Transcription Factors
• Protein Pathways: Axon guidance, B cell receptor signaling pathway, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, T cell receptor signaling pathway, VEGF signaling pathway, Wnt signaling pathway
• Gene Summary: 'This gene is a member of the nuclear factor of activated T cells (NFAT) family. The product of this gene is a DNA-binding protein with a REL-homology region (RHR) and an NFAT-homology region (NHR). This protein is present in the cytosol and only translocates to the nucleus upon T cell receptor (TCR) stimulation, where it becomes a member of the nuclear factors of activated T cells transcription complex. This complex plays a central role in inducing gene transcription during the immune response. Alternate transcriptional splice variants encoding different isoforms have been characterized. [provided by RefSeq, Apr 2012]'
  Transcript Variant: This variant (5) has an alternate first exon, an alternate exon in the 3' end, and uses an alternate splice junction at the 5' end of a coding exon compared to variant 2. The resulting isoform (F) is shorter at the N-terminus and has a shorter and distinct C-terminus compared to isoform C. Variants 5 and 7 both encode the same isoform (F). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.