TOP1MT (NM_001258446) Human Untagged Clone

CAT#: SC332713

TOP1MT (untagged) - Homo sapiens topoisomerase (DNA) I, mitochondrial (TOP1MT), transcript variant 2


  "NM_001258446" in other vectors (2)

Reconstitution Protocol

USD 500.00

5 Weeks*

Size
    • 10 ug

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Specifications

Product Data
Type Human Untagged Clone
Tag Tag Free
Symbol TOP1MT
Vector pCMV6 series
Sequence Data
>NCBI ORF sequence for NM_001258446, the custom clone sequence may differ by one or more nucleotides


ATGTTAGATCATGAATACACAACAAAGGAGGTTTTCCGGAAGAACTTCTTCAATGACTGGCGAAAGGAAA
TGGCGGTGGAAGAGAGGGAAGTCATCAAGAGCCTGGACAAGTGTGACTTCACGGAGATCCACAGATACTT
TGTGGACAAGGCCGCAGCCCGGAAAGTCCTGAGCAGGGAGGAGAAGCAGAAGCTAAAAGAAGAGGCAGAA
AAACTTCAGCAAGAGTTCGGCTACTGTATTTTAGATGGTCACCAAGAAAAAATAGGCAACTTCAAGATTG
AGCCGCCTGGCTTGTTCCGTGGCCGTGGCGACCATCCCAAGATGGGGATGCTGAAGAGAAGGATCACGCC
AGAGGATGTGGTTATCAACTGCAGCAGGGACTCGAAGATCCCCGAGCCGCCGGCGGGGCACCAGTGGAAG
GAGGTGCGCTCCGATAACACCGTCACGTGGCTGGCAGCTTGGACCGAGAGCGTTCAGAACTCCATCAAGT
ACATCATGCTGAACCCTTGCTCGAAGCTGAAGGGGGAGACAGCTTGGCAGAAGTTTGAAACAGCTCGACG
CCTGCGGGGATTTGTGGACGAGATCCGCTCCCAGTACCGGGCTGACTGGAAGTCTCGGGAAATGAAGACG
AGACAGCGGGCGGTGGCCCTGTATTTCATCGATAAGCTGGCACTGAGAGCAGGAAATGAGAAGGAGGACG
GTGAGGCGGCCGACACCGTGGGCTGCTGTTCCCTCCGCGTGGAGCACGTCCAGCTGCACCCGGAGGCCGA
TGGCTGCCAACACGTGGTGGAATTTGACTTCCTGGGGAAGGACTGCATCCGCTACTACAACAGAGTGCCG
GTGGAGAAGCCGGTGTACAAGAACTTACAGCTCTTTATGGAGAACAAGGACCCCCGGGACGACCTCTTCG
ACAGGCTGACCACGACCAGCCTGAACAAGCACCTCCAGGAGCTGATGGACGGGCTGACGGCCAAGGTGTT
CCGGACCTACAACGCCTCCATCACTCTGCAGGAGCAGCTGCGGGCCCTGACGCGCGCCGAGGACAGCATA
GCAGCTAAGATCTTATCCTACAACCGAGCCAACCGAGTCGTGGCCATTCTCTGCAACCATCAGCGAGCAA
CCCCCAGTACGTTCGAGAAGTCGATGCAGAATCTCCAGACGAAGATCCAGGCAAAGAAGGAGCAGGTGGC
TGAGGCCAGGGCAGAGCTGAGGAGGGCGAGGGCTGAGCACAAAGCCCAAGGGGATGGCAAGTCCAGGAGT
GTCCTGGAGAAGAAGAGGCGGCTCCTGGAGAAGCTGCAGGAGCAGCTGGCGCAGCTGAGTGTGCAGGCCA
CGGACAAGGAGGAGAACAAGCAGGTGGCCCTGGGCACGTCCAAGCTCAACTACCTGGACCCCAGGATCAG
CATTGCCTGGTGCAAGCGGTTCAGGGTGCCAGTGGAGAAGATCTACAGCAAAACACAGCGGGAGAGGTTC
GCCTGGGCTCTCGCCATGGCAGGAGAAGACTTTGAATTCTAA


Restriction Sites SgfI-MluI     
ACCN NM_001258446
ORF Size 1512 bp
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Reference Data
RefSeq NM_001258446.1, NP_001245375.1
RefSeq Size 2045
RefSeq ORF 1512
Locus ID 116447
Protein Families Druggable Genome
Gene Summary This gene encodes a mitochondrial DNA topoisomerase that plays a role in the modification of DNA topology. The encoded protein is a type IB topoisomerase and catalyzes the transient breaking and rejoining of DNA to relieve tension and DNA supercoiling generated in the mitochondrial genome during replication and transcription. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, May 2012]
Transcript Variant: This variant (2) differs in the 5' UTR, lacks a portion of the 5' coding region and initiates translation at a downstream, in-frame start codon, compared to variant 1. Variants 2 and 3 encode the same isoform (2), which has a shorter N-terminus compared to isoform 1.

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.