PKMYT1 (NM_001258451) Human Untagged Clone

CAT#: SC332718

PKMYT1 (untagged) - Homo sapiens protein kinase, membrane associated tyrosine/threonine 1 (PKMYT1), transcript variant 4

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: PKMYT1
• Synonyms: MYT1; PPP1R126
• Vector: pCMV6 series
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_001258451, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGCCCATGCCCACGGAGGGCACCCCGCCACCTCTGAGTGGCACCCCCATCCCAGTCCCAGCCTACTTCC
  GCCACGCAGAACCTGGATTCTCCCTCAAGAGGCCCAGGGGGCTCAGCCGGAGCCTCCCACCTCCGCCCCC
  TGCCAAGGGCAGCATTCCCATCAGCCGCCTCTTCCCTCCTCGGACCCCAGGCTGGCACCAGCTGCAGCCC
  CGGCGGGTGTCATTCCGGGGCGAGGCCTCAGAGACTCTGCAGAGCCCTGGGTATGACCCAAGCCGGCCAG
  AGTCCTTCTTCCAGCAGAGCTTCCAGAGGCTCAGCCGCCTGGGCCATGGCTCCTACGGAGAGGTCTTCAA
  GGTGCGCTCCAAGGAGGACGGCCGGCTCTATGCGGTAAAGCGTTCCATGTCACCATTCCGGGGCCCCAAG
  GACCGGGCCCGCAAGTTGGCCGAGGTGGGCAGCCACGAGAAGGTGGGGCAGCACCCATGCTGCGTGCGGC
  TGGAGCAGGCCTGGGAGGAGGGCGGCATCCTGTACCTGCAGACGGAGCTGTGCGGGCCCAGCCTGCAGCA
  ACACTGTGAGGCCTGGGGTGCCAGCCTGCCTGAGGCCCAGGTCTGGGGCTACCTGCGGGACACGCTGCTT
  GCCCTGGCCCATCTGCACAGCCAGGGCCTGGTGCACCTTGATGTCAAGCCTGCCAACATCTTCCTGGGGC
  CCCGGGGCCGCTGCAAGCTGGGTGACTTCGGACTGCTGGTGGAGCTGGGTACAGCAGGAGCTGGTGAGGT
  CCAGGAGGGAGACCCCCGCTACATGGCCCCCGAGCTGCTGCAGGGCTCCTATGGGACAGCAGCGGATGTG
  TTCAGTCTGGGCCTCACCATCCTGGAAGTGGCATGCAACATGGAGCTGCCCCACGGTGGGGAGGGCTGGC
  AGCAGCTGCGCCAGGGCTACCTGCCCCCTGAGTTCACTGCCGGTCTGTCTTCCGAGCTGCGTTCTGTCCT
  TGTCATGATGCTGGAGCCAGACCCCAAGCTGCGGGCCACGGCCGAGGCCCTGCTGGCACTGCCTGTGTTG
  AGGCAGCCGCGGGCCTGGGGTGTGCTGTGGTGCATGGCAGCGGAGGCCCTGAGCCGAGGGTGGGCCCTGT
  GGCAGGCCCTGCTTGCCCTGCTCTGCTGGCTCTGGCATGGGCTGGCTCACCCTGCCAGCTGGCTACAGCC
  CCTGGGCCCGCCAGCCACCCCGCCTGGCTCACCACCCTGCAGTTTGCTCCTGGACAGCAGCCTCTCCAGC
  AACTGGGATGACGACAGCCTAGGGCCTTCACTCTCCCCTGAGGCTGTCCTGGCCCGGACTGTGGGGAGCA
  CCTCCACCCCCCGGAGCAGGTGCACACCCAGGGATGCCCTGGACCTAAGTGACATCAACTCAGAGCCTCC
  TCGGGGCTCCTTCCCCTCCTTTGAGCCTCGGAACCTCCTCAGCCTGTTTGAGGACACCCTAGACCCAACC
  TGA
  
  
• Restriction Sites: SgfI-MluI
• ACCN: NM_001258451
• ORF Size: 1473 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_001258451.1, NP_001245380.1
• RefSeq Size: 2051
• RefSeq ORF: 1473
• Locus ID: 9088
• Protein Families: Druggable Genome, Protein Kinase
• Protein Pathways: Cell cycle, Oocyte meiosis, Progesterone-mediated oocyte maturation
• Gene Summary: This gene encodes a member of the serine/threonine protein kinase family. The encoded protein is a membrane-associated kinase that negatively regulates the G2/M transition of the cell cycle by phosphorylating and inactivating cyclin-dependent kinase 1. The activity of the encoded protein is regulated by polo-like kinase 1. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, May 2012]
  Transcript Variant: This variant (4) differs in the 5' UTR, lacks a portion of the 5' coding region and initiates translation at a downstream, in-frame start codon, compared to variant 1. The encoded isoform (4) has a shorter N-terminus, compared to isoform 1.