ABCB7 (NM_001271697) Human Untagged Clone

CAT#: SC333086

ABCB7 (untagged) - Homo sapiens ATP-binding cassette, sub-family B (MDR/TAP), member 7 (ABCB7), transcript variant 3

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: ABCB7
• Synonyms: ABC7; ASAT; Atm1p; EST140535
• Vector: pCMV6 series
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_001271697, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGGCGCTGCTCGCGATGCATTCTTGGCGCTGGGCGGCCGCGGCGGCTGCTTTCGAAAAGCGCCGGCACT
  CCGCGATTCTGATCCGGCCTTTAGTCTCTGTTAGCGGCTCAGGTCCGCAGTGGAGGCCACATCAACTCGG
  CGCCTTGGGAACCGCTCGAGCCTACCAGATTCCAGAGTCATTAAAAAGTATCACATGGCAGAGATTGGGA
  AAAGGCAATTCAGGACAGTTCTTAGATGCTGCAAAGGCTCTCCAGGTATGGCCACTGATAGAAAAGAGGA
  CATGTTGGCATGGTCATGCAGGAGGAGGACTCCACACAGACCCAAAAGAAGGGGCCATGAATATTGTGGT
  TCCCTTCATGTTTAAATATGCTGTAGACAGCCTCAACCAGATGTCGGGAAACATGCTGAACCTGAGTGAT
  GCACCAAATACAGTTGCAACCATGGCAACAGCAGTTCTGATTGGCTATGGTGTATCAAGAGCTGGAGCTG
  CTTTTTTTAACGAAGTTCGAAATGCAGTATTTGGCAAGGTAGCCCAGAATTCAATCCGAAGAATAGCCAA
  AAATGTCTTTCTCCATCTTCACAACCTGGATCTGGGTTTTCACCTGAGCAGACAGACGGGAGCTTTATCT
  AAGGCTATTGACAGAGGAACAAGGGGTATCAGTTTTGTCCTGAGTGCTTTGGTATTTAATCTTCTTCCCA
  TCATGTTTGAAGTGATGCTTGTCAGTGGTGTTTTGTATTACAAATGCGGTGCCCAGTTTGCTTTGGTAAC
  CCTTGGAACACTTGGTACATACACAGCATTCACAGTTGCAGTCACACGGTGGAGAACTAGATTTAGAATA
  GAAATGAACAAAGCAGATAATGATGCAGGTAATGCTGCTATAGACTCACTGCTGAATTATGAAACTGTGA
  AGTATTTTAATAATGAAAGATATGAAGCACAGAGATATGATGGATTTTTGAAGACGTATGAGACTGCTTC
  ATTGAAAAGTACCTCTACTCTGGCTATGCTGAACTTTGGTCAAAGTGCTATTTTCAGTGTCGGTTTAACA
  GCTATAATGGTGCTCGCCAGTCAGGGAATTGTGGCAGGTACCCTTACTGTTGGAGATCTAGTAATGGTGA
  ATGGACTGCTTTTTCAGCTTTCATTACCCCTGAACTTTCTGGGAACTGTATATAGAGAGACTAGACAAGC
  ACTCATAGATATGAACACCTTGTTTACTCTACTCAAGGTAGACACCCAAATTAAAGACAAAGTGATGGCA
  TCTCCCCTTCAGATCACACCACAGACAGCTACCGTGGCCTTTGATAATGTGCATTTTGAATACATTGAGG
  GCCAGAAAGTCCTTAGTGGAATATCCTTTGAAGTCCCTGCAGGAAAGAAAGTGGCCATTGTAGGAGGTAG
  TGGGTCAGGGAAAAGCACAATAGTGAGGCTATTATTTCGCTTCTATGAGCCTCAAAAGGGTAGCATTTAT
  CTTGCTGGTCAAAATATACAAGATGTGAGCCTGGAAAGCCTTCGGAGGGCAGTGGGAGTGGTACCTCAGG
  ATGCTGTCCTCTTCCATAATACTATTTATTACAACCTCTTATATGGAAACATCAGTGCTTCACCTGAGGA
  AGTGTATGCAGTGGCAAAATTAGCTGGACTTCATGATGCAATTCTTCGAATGCCACATGGATATGACACC
  CAAGTAGGGGAACGAGGACTCAAGCTTTCAGGAGGAGAAAAGCAAAGAGTAGCAATTGCAAGAGCCATTT
  TGAAGGACCCCCCAGTCATACTCTATGATGAAGCTACTTCATCGTTAGATTCGATTACTGAAGAGACTAT
  TCTTGGTGCCATGAAGGATGTGGTCAAACACAGAACTTCTATTTTCATTGCACACAGATTGTCAACAGTG
  GTTGATGCAGATGAAATCATTGTCTTGGATCAGGGTAAGGTAGCCGAACGTGGTACCCACCATGGTTTGC
  TTGCTAACCCTCATAGTATCTATTCAGAAATGTGGCATACACAGAGCAGCCGTGTGCAGAACCATGATAA
  CCCCAAATGGGAAGCAAAGAAAGAAAATATATCCAAAGAGGAGGAAAGAAAGAAACTACAAGAAGAAATT
  GTCAATAGTGTGAAAGGCTGTGGAAACTGTTCGTGCTAA
  
  
• Restriction Sites: SgfI-MluI
• ACCN: NM_001271697
• ORF Size: 2139 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_001271697.1, NP_001258626.1
• RefSeq Size: 2405
• RefSeq ORF: 2139
• Locus ID: 22
• Protein Families: Druggable Genome, Transmembrane
• Protein Pathways: ABC transporters
• Gene Summary: The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance as well as antigen presentation. This gene encodes a half-transporter involved in the transport of heme from the mitochondria to the cytosol. With iron/sulfur cluster precursors as its substrates, this protein may play a role in metal homeostasis. Mutations in this gene have been associated with mitochondrial iron accumulation and isodicentric (X)(q13) and sideroblastic anemia. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Nov 2012]
  Transcript Variant: This variant (3) uses an alternate in-frame splice site in the 5' coding region and lacks an alternate in-frame exon, compared to variant 1. This results in a shorter protein (isoform 3), compared to isoform 1.