NALP6 (NLRP6) (NM_001276700) Human Untagged Clone

CAT#: SC333261

NLRP6 (untagged) - Homo sapiens NLR family, pyrin domain containing 6 (NLRP6), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: NLRP6
• Synonyms: AVR; CLR11.4; NALP6; NAVR; NAVR/AVR; PAN3; PYPAF5
• Vector: pCMV6 series
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_001276700, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGGACCAGCCAGAGGCCCCCTGCTCCAGCACGGGGCCGCGCCTCGCGGTGGCCCGCGAGCTGCTCCTGG
  CTGCGCTGGAGGAACTGAGCCAAGAGCAGCTGAAGCGCTTCCGCCACAAGCTGCGCGACGTGGGCCCGGA
  CGGACGCAGCATCCCGTGGGGGCGGCTGGAGCGCGCGGACGCCGTGGACCTCGCGGAGCAGCTGGCCCAG
  TTCTACGGCCCGGAGCCTGCCCTGGAGGTGGCCCGCAAGACCCTCAAGAGGGCGGACGCGCGCGACGTGG
  CGGCGCAGCTCCAGGAGCGGCGGCTGCAGCGGCTCGGGCTCGGCTCCGGGACGCTGCTCTCCGTGTCCGA
  GTACAAGAAGAAGTACCGGGAGCACGTGCTGCAGCTGCACGCTCGGGTGAAGGAGAGGAACGCCCGCTCC
  GTGAAGATCACCAAGCGCTTCACCAAGCTGCTCATCGCGCCCGAGAGCGCCGCCCCGGAGGAGGCGATGG
  GGCCCGCGGAAGAGCCTGAGCCGGGGCGCGCGCGGCGCTCGGACACGCACACTTTCAACCGCCTCTTCCG
  CCGCGACGAGGAGGGCCGGCGGCCGCTGACCGTGGTGCTGCAGGGCCCGGCGGGCATCGGCAAGACCATG
  GCGGCCAAAAAGATCCTGTACGACTGGGCGGCGGGCAAGCTGTACCAGGGCCAGGTGGACTTCGCCTTCT
  TCATGCCCTGCGGCGAGCTGCTGGAGAGGCCGGGCACGCGCAGCCTGGCTGACCTGATCCTGGACCAGTG
  CCCCGACCGCGGCGCGCCGGTGCCGCAGATGCTGGCCCAGCCGCAGCGGCTGCTCTTCATCCTGGACGGC
  GCGGACGAGCTGCCGGCGCTGGGGGGCCCCGAGGCCGCGCCCTGCACAGACCCCTTCGAGGCGGCGAGCG
  GCGCGCGGGTGCTAGGCGGGCTGCTGAGCAAGGCGCTGCTGCCCACGGCCCTCCTGCTGGTGACCACGCG
  CGCCGCCGCCCCCGGGAGGCTGCAGGGCCGCCTGTGTTCCCCGCAGTGCGCCGAGGTGCGCGGCTTCTCC
  GACAAGGACAAGAAGAAGTATTTCTACAAGTATTTCCGGGATGAGAGGAGGGCCGAGCGCGCCTACCGCT
  TCGTGAAGGAGAACGAGACGCTGTTCGCGCTGTGCTTCGTGCCCTTCGTGTGCTGGATCGTGTGCACCGT
  GCTGCGCCAGCAGCTGGAGCTCGGTCGGGACCTGTCGCGCACGTCCAAGACCACCACGTCAGTGTACCTG
  CTTTTCATCACCAGCGTTCTGAGCTCGGCTCCGGTAGCCGACGGGCCCCGGTTGCAGGGCGACCTGCGCA
  ATCTGTGCCGCCTGGCCCGCGAGGGCGTCCTCGGACGCAGGGCGCAGTTTGCCGAGAAGGAACTGGAGCA
  ACTGGAGCTTCGTGGCTCCAAAGTGCAGACGCTGTTTCTCAGCAAAAAGGAGCTGCCGGGCGTGCTGGAG
  ACAGAGGTCACCTACCAGTTCATCGACCAGAGCTTCCAGGAGTTCCTCGCGGCACTGTCCTACCTGCTGG
  AGGACGGCGGGGTGCCCAGGACCGCGGCTGGCGGCGTTGGGACACTCCTGCGTGGGGACGCCCAGCCGCA
  CAGCCACTTGGTGCTCACCACGCGCTTCCTCTTCGGACTGCTGAGCGCGGAGCGGATGCGCGACATCGAG
  CGCCACTTCGGCTGCATGGTTTCAGAGCGTGTGAAGCAGGAGGCCCTGCGGTGGGTGCAGGGACAGGGAC
  AGGGCTGCCCCGGAGTGGCACCAGAGGTGACCGAGGGGGCCAAAGGGCTCGAGGACACCGAAGAGCCAGA
  GGAGGAGGAGGAGGGAGAGGAGCCCAACTACCCACTGGAGTTGCTGTACTGCCTGTACGAGACGCAGGAG
  GACGCGTTTGTGCGCCAAGCCCTGTGCCGGTTCCCGGAGCTGGCGCTGCAGCGAGTGCGCTTCTGCCGCA
  TGGACGTGGCTGTTCTGAGCTACTGCGTGAGGTGCTGCCCTGCTGGACAGGCACTGCGGCTGATCAGCTG
  CAGATTGGTTGCTGCGCAGGAGAAGAAGAAGAAGAGCCTGGGGAAGCGGCTCCAGGCCAGCCTGGGTGGC
  GGCAGTTCTCAAGGCACCACAAAACAACTGCCAGCCTCCCTTCTTCATCCACTCTTTCAGGCAATGACTG
  ACCCACTGTGCCATCTGAGCAGCCTCACGCTGTCCCACTGCAAACTCCCTGACGCGGTCTGCCGAGACCT
  TTCTGAGGCCCTGAGGGCAGCCCCCGCACTGACGGAGCTGGGCCTCCTCCACAACAGGCTCAGTGAGGCG
  GGACTGCGTATGCTGAGTGAGGGCCTAGCCTGGCCGCAGTGCAGGGTGCAGACGGTCAGGGTACAGCTGC
  CTGACCCCCAGCGAGGGCTCCAGTACCTGGTGGGTATGCTTCGGCAGAGCCCTGCCCTGACCACCCTGGA
  TCTCAGCGGCTGCCAACTGCCCGCCCCCATGGTGACCTACCTGTGTGCAGTCCTGCAGCACCAGGGATGC
  GGCCTGCAGACCCTCAGTCTGGCCTCTGTGGAGCTGAGCGAGCAGTCACTACAGGAGCTTCAGGCTGTGA
  AGAGAGCAAAGCCGGATCTGGTCATCACACACCCAGCGCTGGACGGCCACCCACAACCTCCCAAGGAACT
  CATCTCGACCTTCTGA
  
  
• Restriction Sites: SgfI-RsrII
• ACCN: NM_001276700
• ORF Size: 2676 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_001276700.1, NP_001263629.1
• RefSeq Size: 2760
• RefSeq ORF: 2676
• Locus ID: 171389
• Gene Summary: The protein encoded by this gene binds arginine-vasopressin and may be involved in the arginine-vasopressin-mediated regulation of renal salt-water balance. The encoded protein also mediates inflammatory responses in the colon to allow recovery from intestinal epithelial damage and protects against tumorigenesis and the development of colitis. Finally, this protein can increase activation of NF-kappa-B, activation of CASP1 through interaction with ASC, and cAMP accumulation. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2013]
  Transcript Variant: This variant (2) uses an alternate in-frame exon at the 5' end of an exon compared to variant 1. The resulting isoform (2) lacks a single internal aa compared to isoform 1.