PKD1L2 (NM_001278423) Human Untagged Clone

CAT#: SC335235

PKD1L2 (untagged) - Human polycystic kidney disease 1-like 2 (gene/pseudogene) (PKD1L2), transcript variant 5

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: PKD1L2
• Synonyms: PC1L2
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_001278423, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGGGGGAGGACTCTCCAGTGGCTATGTTCAGCTGGTATTTGGACAACACCCCAACAGAGCAGGCTGAGC
  CCCTCCTGGATGCCTGCAGACTCAGAGGATTTTGGCCAAGGTCCTTAACCCTCCTCCAGAGCAACACCTC
  CACGTTGCTGTTGAACAGCTCGTTTCTGCAGTCCCGGGGAGAGGTCATCCGAATCAGAGCCACAGCACTG
  ACCAGGCATGCCTATGGGGAGGACACCTATGTGATCAGCACTGTGCCTCCCCGTGAGGTGCCTGCCTGCA
  CTATTGCCCCAGAGGAGGGCACCGTTCTGACGAGCTTTGCCATCTTCTGCAACGCCTCCACAGCCCTGGG
  ACCCCTGGAGTTCTGCTTCTGTCTGGAATCAGGTTCCTGCCTACACTGTGGCCCTGAACCTGCCCTCCCA
  TCAGTGTATCTGCCACTTGGAGAGGAGAACAATGACTTTGTGCTGACAGTAGTTATTTCTGCCACCAATC
  GTGCAGGGGACACGCAGCAGACCCAGGCCATGGCTAAGGTGGCACTCGGAGACACATGTGTTGAGGATGT
  AGCATTCCAGGCTGCCGTGTCAGAGAAAATCCCCACAGCTCTGCAAGGCGAGGGTGGCCCCGAGCAGCTC
  CTCCAGCTGGCCAAGGCTGTGTCCTCCATGCTGAACCAAGAGCATGAAAGCCAGGGCTCAGGACAGTCAC
  TGAGCATAGACGTCAGACAGAAGGTCAGAGAGCATGTGCTGGGATCACTGTCTGCAGTCACCACCGGCTT
  GGAGGACGTGCAGAGGGTGCAGGAGCTGGCCGAGGTGCTGAGAGAGGTGACCTGCCGGAGTAAGGAACTC
  ACACCCTCGGCCCAGGGGTCCTGCATGGGCGATTCATGGGAAGGTGCCCCTCCTGCTGCCCATGTATCTC
  ACGCTAGGTGA
  
  
• Restriction Sites: SgfI-MluI
• ACCN: NM_001278423
• ORF Size: 921 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_001278423.1, NP_001265352.1
• RefSeq Size: 1533
• RefSeq ORF: 921
• Locus ID: 114780
• Protein Families: Druggable Genome
• Gene Summary: This gene encodes a member of the polycystin protein family. The encoded protein contains 11 transmembrane domains, a latrophilin/CL-1-like GPCR proteolytic site (GPS) domain, and a polycystin-1, lipoxygenase, alpha-toxin (PLAT) domain. This protein may function as a component of cation channel pores. This gene appears to be a polymorphic pseudogene in humans, and the reference genome encodes a non-functional allele. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2019]
  Transcript Variant: This variant (5) lacks several 5' and 3' exons but includes alternate 5' and 3' exons, and it thus differs in both UTRs, uses a downstream in-frame start codon and has an alternate 3' coding region, compared to variant 1. The encoded isoform (e) is shorter and has a distinct C-terminus, compared to isoform a.