FBXO31 (NM_001282683) Human Untagged Clone

CAT#: SC335654

FBXO31 (untagged) - Human F-box protein 31 (FBXO31), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: FBXO31
• Synonyms: FBX14; Fbx31; FBXO14; MRT45; pp2386
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_001282683, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGTACCTGCCTCCCCATGACCCCCACGTCGATGACCCTATGAGATTCAAGCCTCTGTTCAGGATCCACC
  TGATGGAGAGGAAGGCTGCCACAGTGGAGTGCATGTACGGCCACAAAGGGCCCCACCACGGCCACATCCA
  GATTGTGAAGAAGGATGAGTTCTCCACCAAGTGCAACCAGACGGACCACCACAGGATGTCCGGCGGGAGG
  CAGGAGGAGTTTCGGACGTGGCTGAGGGAGGAATGGGGGCGCACGCTGGAGGACATCTTCCACGAGCACA
  TGCAGGAGCTCATCCTGATGAAGTTCATCTACACCAGTCAGTACGACAACTGCCTGACCTACCGCCGCAT
  CTACCTGCCGCCCAGCCGCCCCGACGACCTCATCAAGCCTGGCCTCTTCAAAGGTACCTATGGCAGCCAC
  GGCCTGGAGATTGTGATGCTCAGCTTCCACGGCCGGCGTGCCAGGGGCACCAAGATCACGGGCGACCCCA
  ACATCCCCGCTGGGCAGCAGACAGTGGAGATCGACCTGAGGCATCGGATCCAGCTGCCCGACCTCGAGAA
  CCAGCGCAACTTCAATGAGCTCTCCCGCATCGTCCTGGAGGTGCGCGAGAGGGTGCGCCAGGAGCAGCAG
  GAAGGCGGGCACGAGGCGGGCGAGGGTCGTGGCCGGCAGGGCCCCCGGGAGTCCCAGCCAAGCCCTGCCC
  AGCCCAGGGCAGAGGCGCCCAGCAAGGGCCCAGATGGGACACCTGGTGAGGATGGTGGCGAGCCTGGGGA
  TGCCGTAGCTGCGGCCGAGCAGCCTGCCCAGTGTGGGCAGGGGCAGCCGTTCGTGCTGCCCGTGGGCGTG
  AGCTCCAGGAATGAGGACTACCCCCGAACCTGCAGGATGTGTTTTTATGGCACAGGCCTCATCGCGGGCC
  ACGGCTTCACCAGCCCTGAACGCACCCCCGGGGTCTTCATCCTCTTCGATGAGGACCGCTTCGGGTTCGT
  CTGGCTGGAGCTGAAATCCTTCAGCCTGTACAGCCGGGTCCAGGCCACCTTCCGGAACGCAGATGCGCCG
  TCCCCACAGGCCTTCGATGAGATGCTCAAGAACATTCAGTCCCTCACCTCCTGA
  
  
• Restriction Sites: SgfI-MluI
• ACCN: NM_001282683
• ORF Size: 1104 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_001282683.1, NP_001269612.1
• RefSeq Size: 5738
• RefSeq ORF: 1104
• Locus ID: 79791
• Protein Families: Druggable Genome
• Gene Summary: This gene is a member of the F-box family. Members are classified into three classes according to the substrate interaction domain, FBW for WD40 repeats, FBL for leucing-rich repeats, and FBXO for other domains. This protein, classified into the last category because of the lack of a recognizable substrate binding domain, has been proposed to be a component of the SCF ubiquitination complex. It is thought to bind and recruit substrate for ubiquitination and degradation. This protein may have a role in regulating the cell cycle as well as dendrite growth and neuronal migration. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013]
  Transcript Variant: This variant (2) represents use of an alternate promoter and thus differs in the 5' UTR and 5' coding region compared to variant 1. These differences cause translation initiation at a downstream AUG and result in an isoform (2) with a shorter N-terminus, compared to isoform 1.