IL18R1 (NM_001282399) Human Untagged Clone

CAT#: SC335784

IL18R1 (untagged) - Human interleukin 18 receptor 1 (IL18R1), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: IL18R1
• Synonyms: CD218a; CDw218a; IL-1Rrp; IL1RRP; IL18RA
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_001282399, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGAACTGTAAAAAGCTACTACTGGAGAACAATAAAAACCCAACGATAAAGAAGAACGCCGAGTTTGAAG
  ATCAGGGGTATTACTCCTGCGTGCATTTCCTTCATCATAATGGAAAACTATTTAATATCACCAAAACCTT
  CAATATAACAATAGTGGAAGATCGCAGTAATATAGTTCCGGTTCTTCTTGGACCAAAGCTTAACCATGTT
  GCAGTGGAATTAGGAAAAAACGTAAGGCTCAACTGCTCTGCTTTGCTGAATGAAGAGGATGTAATTTATT
  GGATGTTCGGGGAAGAAAATGGATCGGATCCTAATATACATGAAGAGAAAGAAATGAGAATTATGACTCC
  AGAAGGCAAATGGCATGCTTCAAAAGTATTGAGAATTGAAAATATTGGTGAAAGCAATCTAAATGTTTTA
  TATAATTGCACTGTGGCCAGCACGGGAGGCACAGACACCAAAAGCTTCATCTTGGTGAGAAAAGACATGG
  CTGATATCCCAGGCCACGTCTTCACAAGAGGAATGATCATAGCTGTTTTGATCTTGGTGGCAGTAGTGTG
  CCTAGTGACTGTGTGTGTCATTTATAGAGTTGACTTGGTTCTATTTTATAGACATTTAACGAGAAGAGAT
  GAAACATTAACAGATGGAAAAACATATGATGCTTTTGTGTCTTACCTAAAAGAATGCCGACCTGAAAATG
  GAGAGGAGCACACCTTTGCTGTGGAGATTTTGCCCAGGGTGTTGGAGAAACATTTTGGGTATAAGTTATG
  CATATTTGAAAGGGATGTAGTGCCTGGAGGAGCTGTTGTTGATGAAATCCACTCACTGATAGAGAAAAGC
  CGAAGACTAATCATTGTCCTAAGTAAAAGTTATATGTCTAATGAGGTCAGGTATGAACTTGAAAGTGGAC
  TCCATGAAGCATTGGTGGAAAGAAAAATTAAAATAATCTTAATTGAATTTACACCTGTTACTGACTTCAC
  ATTCTTGCCCCAATCACTAAAGCTTTTGAAATCTCACAGAGTTCTGAAGTGGAAGGCCGATAAATCTCTT
  TCTTATAACTCAAGGTTCTGGAAGAACCTTCTTTACTTAATGCCTGCAAAAACAGTCAAGCCAGGTAGAG
  ACGAACCGGAAGTCTTGCCTGTTCTTTCCGAGTCTTAA
  
  
• Restriction Sites: SgfI-MluI
• ACCN: NM_001282399
• ORF Size: 1158 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_001282399.1, NP_001269328.1
• RefSeq Size: 3471
• RefSeq ORF: 1158
• Locus ID: 8809
• Protein Families: Druggable Genome, Transmembrane
• Protein Pathways: Cytokine-cytokine receptor interaction
• Gene Summary: The protein encoded by this gene is a cytokine receptor that belongs to the interleukin 1 receptor family. This receptor specifically binds interleukin 18 (IL18), and is essential for IL18 mediated signal transduction. IFN-alpha and IL12 are reported to induce the expression of this receptor in NK and T cells. This gene along with four other members of the interleukin 1 receptor family, including IL1R2, IL1R1, ILRL2 (IL-1Rrp2), and IL1RL1 (T1/ST2), form a gene cluster on chromosome 2q. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2013]
  Transcript Variant: This variant (2) lacks an exon in the 5' region but has an additional exon in a downstream region, compared to variant 1. The resulting isoform (2) has a shorter N-terminus, compared to isoform 1.