NPSR1 (NM_001300935) Human Untagged Clone

CAT#: SC335813

NPSR1 (untagged) - Human neuropeptide S receptor 1 (NPSR1), transcript variant 5


  "NM_001300935" in other vectors (1)

Reconstitution Protocol

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Size
    • 10 ug

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Specifications

Product Data
Type Human Untagged Clone
Tag Tag Free
Symbol NPSR1
Synonyms ASRT2; GPR154; GPRA; NPSR; PGR14; VRR1
Vector pCMV6-Entry
E. coli Selection Kanamycin (25 ug/mL)
Mammalian Cell Selection Neomycin
Sequence Data
>NCBI ORF sequence for NM_001300935, the custom clone sequence may differ by one or more nucleotides


ATGCCAGCCAACTTCACAGAGGGCAGCTTCGATTCCAGTGGGACCGGGCAGACGCTGGATTCTTCCCCAG
TGGCTTGCACTGAAACAGTGACTTTTACTGAAGTGGTGGAAGGAAAGGAATGGGGTTCCTTCTACTACTC
CTTTAAGACTGAGCAATTGATAACTCTGTGGGTCCTCTTTGTTTTTACCATTGTTGGAAACTCCGTTGTG
CTTTTTTCCACATGGAGGAGAAAGAAGAAGTCAAGAATGACCTTCTTTGTGACTCAGCTGGCCATCACAG
ATTCTTTCACAGGACTGGTCAACATCTTGACAGATATTAATTGGCGATTCACTGGAGACTTCACGGCACC
TGACCTGGTTTGCCGAGTGGTCCGCTATTTGCAGGTTGTGCTGCTCTACGCCTCTACCTACGTCCTGGTG
TCCCTCAGCATAGACAGATACCATGCCATCGTCTACCCCATGAAGTTCCTTCAAGGAGAAAAGCAAGCCA
GGGTCCTCATTGTGATCGCCTGGAGCCTGTCTTTTCTGTTCTCCATTCCCACCCTGATCATATTTGGGAA
GAGGACACTGTCCAACGGTGAAGTGCAGTGCTGGGCCCTGTGGCCTGACGACTCCTACTGGACCCCATAC
ATGACCATCGTGGCCTTCCTGGTGTACTTCATCCCTCTGACAATCATCAGCATCATGTATGGCATTGTGA
TCCGAACTATTTGGATTAAAAGCAAAACCTACGAAACAGTGATTTCCAACTGCTCAGATGGGAAACTGTG
CAGCAGCTATAACCGAGGACTCATCTCAAAGGCAAAAATCAAGGCTATCAAGTATAGCATCATCATCATT
CTTGCCTTCATCTGCTGTTGGAGTCCATACTTCCTGTTTGACATTTTGGACAATTTCAACCTCCTTCCAG
ACACCCAGGAGCGTTTCTATGCCTCTGTGATCATTCAGAACCTGCCAGCATTGAATAGTGCCATCAACCC
CCTCATCTACTGTGTCTTCAGCAGCTCCATCTCTTTCCCCTGCAGGGCTAATAGCAGTGTCTACCTGTTG
GCCTGTGATGTCTCTGTCCTCTGGGCTCTGGTGCTGACCAGTGAGAAGGAGAGCTGTGAGTCATGGAGAA
GGAAGGGAGCAAAGATCACAGGATTCCAGAATGACGTTCCGGGAGAGAACTGA


Restriction Sites SgfI-MluI     
ACCN NM_001300935
ORF Size 1173 bp
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Reference Data
RefSeq NM_001300935.1, NP_001287864.1
RefSeq Size 1713
RefSeq ORF 1173
Locus ID 387129
Protein Families Druggable Genome, Transmembrane
Gene Summary This gene encodes a member of the vasopressin/oxytocin subfamily of G protein-coupled receptors. The encoded membrane protein acts as a receptor for neuropeptide S and affects a variety of cellular processes through its signaling. Increased expression of this gene in ciliated cells of the respiratory epithelium and in bronchial smooth muscle cells is associated with asthma. Polymorphisms in this gene have also been associated with asthma susceptibility, panic disorders, inflammatory bowel disease, and rheumatoid arthritis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014]
Transcript Variant: This variant (5) includes an alternate exon in the 3' coding region, which results in a frameshift, compared to variant 1. The encoded isoform (G) has a longer and distinct C-terminus, compared to isoform A.

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