SYT8 (NM_001290334) Human Untagged Clone

CAT#: SC335881

SYT8 (untagged) - Human synaptotagmin VIII (SYT8), transcript variant 4

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: SYT8
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_001290334, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGCTCCACCTGCATGGCTGGCAAACCATGGGTAGAAAGATGGGGCACCCACCAGTCTCTCCCAGTGCCC
  CGGCCCCAGCTGGCACCACAGCTATACCTGGGCTTATTCCAGACCTTGTCGCCGGGACCCCCTGGCCCCG
  CTGGGCTCTCATTGCCGGCGCCCTTGCCGCGGGCGTCCTCCTCGTCTCCTGCCTCCTCTGTGCTGCCTGC
  TGCTGCTGCCGCCGCCACAGGAAGAAGCCCAGGGACAAGGAGTCCGTGGGTCTGGGCAGTGCCCGCGGCA
  CCACCACCACCCACCTGGTGCAACCTGATGTGGATGGCCTGGAGTCCAGCCCGGGGGATGCTCAGCAATG
  GGGGCGCCTGCAGCTCTCCCTGGAGTTCGACTTTGGAAGCCAGGAGATCAGGGTGGGCCTGAGGCAGGCA
  GCCGACCTGAGGCCTGGGGGCACCGTGGACCCCTATGCCCGGGTCAGCGTCTCCACCCAGGCCGGACACA
  GACATGAGACAAAAGTGCACCGAGGCACGCTCTGCCCCGTGTTTGACGAGACCTGCTGCTTCCACATCCC
  GCAGGCGGAGCTGCCAGGGGCCACCCTGCAGGTGCAGCTTTTCAACTTCAAGCGCTTCTCGGGGCATGAG
  CCCCTGGGTGAGCTCCGTCTGCCACTGGGCACCGTGGATCTGCAGCATGTTCTGGAGCACTGGTACCTGC
  TGGGCCCGCCGGCTGCCACTCAGCCCGAGCAGGTCGGGGAGCTGTGCTTCTCTCTCCGGTACGTGCCCAG
  CTCAGGCCGGCTGACCGTGGTGGTGCTGGAGGCTCGAGGCCTGCGTCCAGGACTTGCAGAGCCCTACGTG
  AAGGTCCAGCTCATGCTGAACCAGAGGAAGTGGAAGAAGAGAAAGACAGCCACCAAAAAGGGCACGGCGG
  CCCCCTACTTCAATGAGGCCTTCACCTTCCTGGTGCCCTTCAGCCAGGTCCAGAATGTGGACCTGGTGCT
  GGCTGTCTGGGACCGCAGCCTGCCGCTCCGAACTGAGCCCGTAGGCAAGGTGCACCTGGGTGCCCGGGCC
  TCGGGGCAGCCCCTGCAGCACTGGGCAGACATGCTGGCCCACGCCCGGCGGCCCATTGCCCAGCGGCACC
  CCCTGCGGCCAGCCAGGGAGGTGGACCGCATGCTGGCCCTGCAGCCCCGCCTTCGCCTGCGCCTGCCCTT
  GCCCCACTCCTGA
  
  
• Restriction Sites: SgfI-MluI
• ACCN: NM_001290334
• ORF Size: 1203 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_001290334.1, NP_001277263.1
• RefSeq Size: 1555
• RefSeq ORF: 1203
• Locus ID: 90019
• Protein Families: Transmembrane
• Gene Summary: This gene encodes a member of the synaptotagmin protein family. Synaptotagmins are membrane proteins that are important in neurotransmission and hormone secretion, both of which involve regulated exocytosis. Expression of the encoded protein in human pancreatic islets has been connected to activity of the promoter for the insulin gene, on the same chromosome several hundred kilobases away (PMID: 21336277 and 22928559). This association would link response to gluclose to insulin secretion. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Mar 2014]
  Transcript Variant: This variant (4) uses an alternate in-frame splice site, and an alternate upstream translation start, compared to variant 1. The encoded protein (isoform 4) is shorter and has a distinct N-terminus, compared to isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.