Cytochrome P450 26B (CYP26B1) (NM_001277742) Human Untagged Clone

CAT#: SC336125

CYP26B1 (untagged) - Human cytochrome P450, family 26, subfamily B, polypeptide 1 (CYP26B1), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: CYP26B1
• Synonyms: CYP26A2; P450RAI-2; P450RAI2; RHFCA
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_001277742, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGCTCTTTGAGGGCTTGGATCTGGTGTCGGCGCTGGCCACCCTCGCCGCGTGCCTGGTGTCCGTGACGC
  TGCTGCTGGCCGTGTCGCAGCAGCTGTGGCAGCTGCGCTGGGCCGCCACTCGCGACAAGAGCTGCAAGCT
  GCCCATCCCCAAGGGATCCATGGGCTTCCCGCTCATCGGAGAGACCGGCCACTGGCTGCTGCAGGTCTTC
  TCCAAGATCTTCAGCCACGAGGCCCTGGAGAGTTACCTGCCCAAGATCCAGCTGGTGATCCAGGACACAC
  TGCGCGCCTGGAGCAGCCACCCCGAGGCCATCAACGTGTACCAGGAGGCGCAGAAGCTGACCTTCCGCAT
  GGCCATCCGGGTGCTGCTGGGCTTCAGCATCCCTGAGGAGGACCTTGGGCACCTCTTTGAGGTCTACCAG
  CAGTTTGTGGACAATGTCTTCTCCCTGCCTGTCGACCTGCCCTTCAGTGGCTACCGGCGGGGCATTCAGG
  CTCGGCAGATCCTGCAGAAGGGGCTGGAGAAGGCCATCCGGGAGAAGCTGCAGTGCACACAGGGCAAGGA
  CTACTTGGACGCCCTGGACCTCCTCATTGAGAGCAGCAAGGAGCACGGGAAGGAGATGACCATGCAGGAG
  CTGAAGGACGGGACCCTGGAGCTGATCTTTGCGGCCTATGCCACCACGGCCAGCGCCAGCACCTCACTCA
  TCATGCAGCTGCTGAAGCACCCCACTGTGCTGGAGAAGCTGCGGGATGAGCTGCGGGCTCATGGCATCCT
  GCACAGTGGCGGCTGCCCCTGCGAGGGCACACTGCGCCTGGACACGCTCAGTGGGCTGCGCTACCTGGAC
  TGCGTCATCAAGGAGGTCATGCGCCTGTTCACGCCCATTTCCGGCGGCTACCGCACTGTGCTGCAGACCT
  TCGAGCTTGATGGTTTCCAGATCCCCAAAGGCTGGAGTGTCATGTATAGCATCCGGGACACCCATGACAC
  AGCGCCCGTGTTCAAAGACGTGAACGTGTTCGACCCCGATCGCTTCAGCCAGGCGCGGAGCGAGGACAAG
  GATGGCCGCTTCCATTACCTCCCGTTCGGTGGCGGTGTCCGGACCTGCCTGGGCAAGCACCTGGCCAAGC
  TGTTCCTGAAGGTGCTGGCGGTGGAGCTGGCTAGCACCAGCCGCTTTGAGCTGGCCACACGGACCTTCCC
  CCGCATCACCTTGGTCCCCGTCCTGCACCCCGTGGATGGCCTCAGCGTCAAGTTCTTTGGCCTGGACTCC
  AACCAGAACGAGATCCTGCCGGAGACGGAGGCCATGCTGAGCGCCACAGTCTAA
  
  
• Restriction Sites: SgfI-MluI
• ACCN: NM_001277742
• ORF Size: 1314 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_001277742.1, NP_001264671.1
• RefSeq Size: 4342
• RefSeq ORF: 1314
• Locus ID: 56603
• Protein Families: Druggable Genome, P450
• Protein Pathways: Retinol metabolism
• Gene Summary: This gene encodes a member of the cytochrome P450 superfamily. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. The encoded protein is localized to the endoplasmic reticulum, and functions as a critical regulator of all-trans retinoic acid levels by the specific inactivation of all-trans retinoic acid to hydroxylated forms. Mutations in this gene are associated with radiohumeral fusions and other skeletal and craniofacial anomalies, and increased levels of the encoded protein are associated with atherosclerotic lesions. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2013]
  Transcript Variant: This variant (2) lacks an in-frame exon in the coding region, compared to variant 1. The encoded isoform (2) is shorter, compared to isoform 1.