CDC2L6 (CDK19) (NM_001300964) Human Untagged Clone

CAT#: SC336152

CDK19 (untagged) - Human cyclin-dependent kinase 19 (CDK19), transcript variant 4

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: CDK19
• Synonyms: bA346C16.3; CDC2L6; CDK11
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_001300964, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGTCGGCTTGTAGAGAGATTGCACTTTTGCGAGAATTGAAGCACCCTAATGTGATTGCATTGCAGAAGG
  TGTTCCTTTCTCACAGTGACAGGAAGGTATGGCTGCTGTTTGATTATGCAGAGCATGACTTGTGGCATAT
  TATTAAGTTTCACCGTGCATCAAAAGCAAATAAAAAGCCCATGCAGTTGCCAAGATCTATGGTTAAATCC
  TTACTTTACCAGATTCTTGATGGTATCCATTACCTCCATGCAAATTGGGTGCTTCACAGAGACTTGAAAC
  CAGCAAATATCCTAGTAATGGGAGAAGGTCCTGAGAGGGGGAGAGTCAAAATAGCTGACATGGGTTTTGC
  CAGATTATTCAATTCTCCTCTAAAGCCACTAGCAGATTTGGATCCAGTAGTTGTGACATTTTGGTATCGG
  GCTCCAGAACTTTTGCTTGGTGCAAGGCATTATACAAAGGCCATTGATATATGGGCAATAGGTTGTATAT
  TTGCTGAATTGTTGACTTCGGAACCTATTTTTCACTGTCGTCAGGAAGATATAAAAACAAGCAATCCCTT
  TCATCATGATCAACTGGATCGGATATTTAGTGTCATGGGGTTTCCTGCAGATAAAGACTGGGAAGATATT
  AGAAAGATGCCAGAATATCCCACACTTCAAAAAGACTTTAGAAGAACAACGTATGCCAACAGTAGCCTCA
  TAAAGTACATGGAGAAACACAAGGTCAAGCCTGACAGCAAAGTGTTCCTCTTGCTTCAGAAACTCCTGAC
  CATGGATCCAACCAAGAGAATTACCTCGGAGCAAGCTCTGCAGGATCCCTATTTTCAGGAGGACCCTTTG
  CCAACATTAGATGTATTTGCCGGCTGCCAGATTCCATACCCCAAACGAGAATTCCTTAATGAAGATGATC
  CTGAAGAAAAAGGTGACAAGAATCAGCAACAGCAGCAGAACCAGCATCAGCAGCCCACAGCCCCTCCACA
  GCAGGCAGCAGCCCCTCCACAGGCGCCCCCACCACAGCAGAACAGCACCCAGACCAACGGGACCGCAGGT
  GGGGCTGGGGCCGGGGTCGGGGGCACCGGAGCAGGGTTGCAGCACAGCCAGGACTCCAGCCTGAACCAGG
  TGCCTCCAAACAAGAAGCCACGGCTAGGGCCTTCAGGCGCAAACTCAGGTGGACCTGTGATGCCCTCGGA
  TTATCAGCACTCCAGTTCTCGCCTGAATTACCAAAGCAGCGTTCAGGGATCCTCTCAGTCCCAGAGCACA
  CTTGGCTACTCTTCCTCGTCTCAGCAGAGCTCACAGTACCACCCATCTCACCAGGCCCACCGGTACTGA
  
  
• Restriction Sites: SgfI-MluI
• ACCN: NM_001300964
• ORF Size: 1329 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_001300964.1, NP_001287893.1
• RefSeq Size: 6016
• RefSeq ORF: 1329
• Locus ID: 23097
• Protein Families: Druggable Genome, Protein Kinase
• Gene Summary: This gene encodes a protein that is one of the components of the Mediator co-activator complex. The Mediator complex is a multi-protein complex required for transcriptional activation by DNA binding transcription factors of genes transcribed by RNA polymerase II. The protein encoded by this gene is similar to cyclin-dependent kinase 8 which can also be a component of the Mediator complex. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2014]
  Transcript Variant: This variant (4) represents use of an alternate promoter and therefore differs in the 5' UTR and 5' coding region, compared to variant 1. These differences cause translation initiation at a downstream start codon and result in an isoform (3) with a shorter N-terminus, compared to isoform 1. Variants 3 and 4 encode the same isoform (3).