PNMA3 (NM_001282535) Human Untagged Clone

CAT#: SC336224

PNMA3 (untagged) - Human paraneoplastic Ma antigen 3 (PNMA3), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: PNMA3
• Synonyms: MA3; MA5
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_001282535, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGCCGTTGACCTTGTTACAGGACTGGTGTCGGGGGGAACACCTGAACACCCGGAGGTGCATGCTCATCC
  TGGGGATCCCCGAGGACTGTGGCGAGGATGAGTTTGAGGAGACACTCCAGGAGGCTTGCAGGCACCTGGG
  CAGATACAGGGTGATTGGCAGGATGTTTAGGAGGGAGGAGAACGCCCAGGCGATTCTACTGGAGCTGGCA
  CAAGATATCGACTATGCTTTGCTCCCAAGGGAAATACCAGGAAAGGGGGGGCCCTGGGAAGTGATTGTAA
  AACCCCGTAACTCAGATGGGGAATTTCTCAACAGACTGAACCGCTTCTTAGAGGAGGAGAGGCGGACCGT
  GTCAGATATGAACCGAGTCCTCGGGTCGGACACCAATTGTTCGGCTCCAAGAGTGACTATATCACCAGAG
  TTCTGGACCTGGGCCCAGACTCTGGGGGCAGCAGTGCAGCCTCTGCTAGAACAAATGTTGTACCGAGAAC
  TAAGAGTGTTTTCTGGGAACACCATATCCATCCCAGGTGCACTGGCCTTTGATGCCTGGCTTGAGCACAC
  CACTGAGATGCTACAGATGTGGCAGGTGCCCGAGGGGGAAAAGAGGCGGAGGCTGATGGAATGCTTACGG
  GGCCCTGCTCTCCAGGTGGTCAGTGGGCTCCGGGCCAGCAATGCTTCCATAACTGTGGAGGAGTGCCTGG
  CTGCCTTGCAGCAGGTGTTCGGACCTGTGGAGAGCCATAAAATTGCCCAGGTGAAGTTGTGTAAAGCCTA
  TCAGGAGGCAGGAGAGAAAGTATCTAGCTTTGTGTTACGTTTGGAACCCCTGCTCCAAAGAGCTGTAGAA
  AACAATGTGGTATCACGTAGAAACGTGAATCAGACTCGCCTGAAACGAGTCTTAAGTGGGGCCACCCTTC
  CTGACAAACTCCGAGATAAGCTTAAGCTGATGAAACAGCGAAGGAAGCCTCCTGGTTTCCTGGCCCTGGT
  GAAGCTCCTGCGTGAGGAGGAGGAATGGGAGGCCACTTTAGGTCCAGATAGGGAGAGTCTGGAGGGGCTG
  GAAGTAGCCCCAAGGCCACCTGCCAGGATCACTGGGGTTGGGGCAGTACCTCTCCCTGCCTCTGGCAACA
  GTTTTGATGCGAGGCCTTCCCAGGGCTACCGGCGCCGGAGGGGCAGAGGCCAACACCGAAGGGGTGGTGT
  GGCAAGGGCTGGCTCTCGAGGCTCAAGAAAACGGAAACGCCACACATTCTGCTATAGCTGTGGGGAAGAC
  GGCCACATCAGGGTACAGTGCATCAACCCCTCCAACCTGCTCTTGGCCAAGGAGACAAAAGAGATATTGG
  AAGGAGGGGAAAGAGAAGCCCAGACAAACAGCAGATGA
  
  
• Restriction Sites: SgfI-MluI
• ACCN: NM_001282535
• ORF Size: 1368 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_001282535.1, NP_001269464.1
• RefSeq Size: 3647
• RefSeq ORF: 1368
• Locus ID: 29944
• Gene Summary: The protein encoded by this gene belongs to the paraneoplastic antigen MA (PNMA) family, which shares homology with retroviral Gag proteins. The PNMA antigens are highly expressed in the brain and also in a range of tumors associated with serious neurological phenotypes. PMID:16407312 reports the presence of a functional -1 ribosomal frameshift signal (consisting of a heptanucleotide shift motif followed 3' by a pseudoknot structure) in this gene, however, the frame-shifted product has not been characterized. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2013]
  Transcript Variant: This variant (2) is alternatively spliced in the 3' coding region, which results in a frame-shift compared to variant 1. The resulting isoform (2) is shorter with a distinct C-terminus compared to isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.