GABRA2 (NM_001286827) Human Untagged Clone
CAT#: SC336229
GABRA2 (untagged) - Human gamma-aminobutyric acid (GABA) A receptor, alpha 2 (GABRA2), transcript variant 3
"NM_001286827" in other vectors (1)
Product Images
Specifications
Product Data | |
Type | Human Untagged Clone |
Tag | Tag Free |
Symbol | GABRA2 |
Vector | pCMV6-Entry |
E. coli Selection | Kanamycin (25 ug/mL) |
Mammalian Cell Selection | Neomycin |
Sequence Data |
>NCBI ORF sequence for NM_001286827, the custom clone sequence may differ by one or more nucleotides
ATGAGGCTAAAAATAACATTACCATCTTTACGAGAATTCTTGACAGACTTCTGGATGGTTACGATAATCG GCTTAGACCAGGACTGGGAGGAATATACAATTGATGTTTTCTTTCGACAAAAATGGAAAGATGAACGTTT AAAATTTAAAGGTCCTATGAATATCCTTCGACTAAACAATTTAATGGCTAGCAAAATCTGGACTCCAGAT ACCTTTTTTCACAATGGGAAAAAATCAGTAGCTCATAATATGACAATGCCAAATAAGTTGCTTCGAATTC AGGATGATGGGACTCTGCTGTATACCATGAGGCTTACAGTTCAAGCTGAATGCCCAATGCACTTGGAGGA TTTCCCAATGGATGCTCATTCATGTCCTCTGAAATTTGGCAGCTATGCATATACAACTTCAGAGGTCACT TATATTTGGACTTACAATGCATCTGATTCAGTACAGGTTGCTCCTGATGGCTCTAGGTTAAATCAATATG ACCTGCTGGGCCAATCAATCGGAAAGGAGACAATTAAATCCAGTACAGGTGAATATACTGTAATGACAGC TCATTTCCACCTGAAAAGAAAAATTGGGTATTTTGTGATTCAAACCTATCTGCCTTGCATCATGACTGTC ATTCTCTCCCAAGTTTCATTCTGGCTTAACAGAGAATCTGTGCCTGCAAGAACTGTGTTTGGAGTAACAA CTGTCCTAACAATGACAACTCTAAGCATCAGTGCTCGGAATTCTCTCCCCAAAGTGGCTTATGCAACTGC CATGGACTGGTTTATTGCTGTTTGTTATGCATTTGTGTTCTCTGCCCTAATTGAATTTGCAACTGTTAAT TACTTCACCAAAAGAGGATGGGCTTGGGATGGGAAGAGTGTAGTAAATGACAAGTCCCCTTCAATAAAAG CTGAAGGCATTACATTAACATACAACTCAGTGAAAGCAATTCTTCAAGGAGCTAAGCTAATATGGTCCAA GTATATAGCTTTCTCATGGCCCAGTTTATTCCAAGAAAAGACTTTAGAGTACTTAGAGAAGTGGATGGAC TGTTTAACCTTCAAACAATCTTCTAAAAAAGAAAAGGCTTCCGTTATGATACAGAACAACGCTTATGCAG TGGCTGTTGCCAATTATGCCCCGAATCTTTCAAAAGATCCAGTTCTCTCCACCATCTCCAAGAGTGCAAC CACGCCAGAACCCAACAAGAAGCCAGAAAACAAGCCAGCTGAAGCAAAGAAAACTTTCAACAGTGTTAGC AAAATTGACAGAATGTCCAGAATAGTTTTTCCAGTTTTGTTTGGTACCTTTAATTTAGTTTACTGGGCTA CATATTTAAACAGAGAACCTGTATTAGGGGTCAGTCCTTGA |
Restriction Sites | SgfI-MluI |
ACCN | NM_001286827 |
OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
Product Components | The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones. |
Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
Reference Data | |
RefSeq | NM_001286827.1, NP_001273756.1 |
RefSeq Size | 2538 bp |
RefSeq ORF | 1371 bp |
Locus ID | 2555 |
Cytogenetics | 4p12 |
Protein Families | Druggable Genome, Ion Channels: Cys-loop Receptors, Transmembrane |
Protein Pathways | Neuroactive ligand-receptor interaction |
Gene Summary | 'GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. At least 16 distinct subunits of GABA-A receptors have been identified. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2013]' Transcript Variant: This variant (3) lacks an alternate exon in the 5' end and contains an alternate in-frame exon in the 3' end, which leads to the use of a downstream start codon compared to variant 1. The resulting isoform (b) has a shorter and distinct N-terminus and contains an alternate segment compared to isoform a. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. |
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Other Versions
SKU | Description | Size | Price |
---|---|---|---|
RC238335 | GABRA2 (myc-DDK-tagged) - Human gamma-aminobutyric acid (GABA) A receptor, alpha 2 (GABRA2), transcript variant 3 |
USD 420.00 |
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