PI 3 Kinase p55 gamma (PIK3R3) (NM_001303428) Human Untagged Clone

CAT#: SC336358

PIK3R3 (untagged) - Human phosphoinositide-3-kinase, regulatory subunit 3 (gamma) (PIK3R3), transcript variant 4

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: PIK3R3
• Synonyms: p55; p55-GAMMA; p55PIK
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_001303428, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGCCTGCTGTCCCCCCTCCCGGCGCGGTTGGGTGGCGCCTCAGCGGCGCGATGTACAATACGGTGTGGA
  GTATGGACCGCGATGACGCAGACTGGAGGGAGGTGATGATGCCCTATTCGACAGAACTGATATTTTATAT
  TGAAATGGATCCTCCAGCTCTTCCACCAAAGCCACCTAAGCCAATGACTTCAGCAGTTCCAAATGGAATG
  AAGGACAGTTCTGTTTCTCTTCAGGATGCAGAATGGTACTGGGGGGATATTTCAAGGGAGGAGGTAAATG
  ACAAATTGCGGGATATGCCAGATGGGACCTTCTTGGTCCGAGATGCCTCAACAAAAATGCAGGGAGATTA
  TACTTTGACTTTGCGGAAGGGAGGCAATAATAAGTTAATAAAGATCTATCACCGGGATGGTAAATATGGC
  TTTTCTGATCCTCTGACATTTAATTCCGTGGTGGAGCTCATTAACCACTATCACCATGAATCTCTTGCTC
  AGTACAATCCCAAACTTGATGTGAAGCTGATGTACCCAGTGTCCAGATACCAACAGGATCAGTTGGTAAA
  AGAAGATAATATTGATGCAGTAGGTAAAAAACTGCAAGAATACCACTCTCAGTATCAGGAGAAGAGTAAA
  GAGTATGATAGGCTGTATGAAGAATATACTAGAACATCCCAGGAAATACAGATGAAGAGGACTGCAATAG
  AAGCTTTTAATGAAACAATTAAAATATTTGAAGAGCAGTGTCACACACAAGAACAACATAGCAAAGAATA
  TATTGAGCGATTTCGCAGAGAGGGGAATGAAAAGGAGATTGAACGAATTATGATGAATTATGATAAATTG
  AAATCACGTCTGGGTGAGATTCATGATAGCAAAATGCGTCTAGAGCAGGATTTGAAGAATCAAGCTTTGG
  ACAACCGAGAAATAGATAAAAAAATGAATAGCATCAAACCTGACCTGATCCAGCTGCGAAAGATCCGAGA
  TCAACACCTTGTATGGCTCAATCACAAAGGAGTGAGACAGAAACGCCTGAATGTCTGGCTGGGAATTAAG
  AATGAGGATGCTGATGAGAACTATTTTATCAATGAGGAAGATGAAAACCTGCCCCATTATGATGAGAAAA
  CCTGGTTTGTTGAGGATATCAATCGAGTACAAGCAGAGGACTTGCTTTATGGGAAACCTGATGGTGCATT
  CTTAATTCGTGAGAGTAGCAAGAAAGGATGCTATGCTTGCTCTGTGGTGGCCGATGGGGAAGTGAAGCAC
  TGTGTGATCTACAGCACTGCTCGGGGCTATGGCTTTGCAGAGCCCTACAACCTGTACAGCTCTCTGAAGG
  AGCTAGTGCTCCATTACCAGCAGACATCCTTGGTTCAGCACAACGACTCCCTCAACGTCAGGCTTGCCTA
  CCCTGTTCATGCACAGATGCCCTCGCTTTGCAGATAA
  
  
• Restriction Sites: SgfI-MluI
• ACCN: NM_001303428
• ORF Size: 1437 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_001303428.1, NP_001290357.1
• RefSeq Size: 5037
• RefSeq ORF: 1437
• Locus ID: 8503
• Protein Families: Druggable Genome
• Protein Pathways: Acute myeloid leukemia, Apoptosis, B cell receptor signaling pathway, Chemokine signaling pathway, Chronic myeloid leukemia, Colorectal cancer, Endometrial cancer, ErbB signaling pathway, Fc epsilon RI signaling pathway, Fc gamma R-mediated phagocytosis, Focal adhesion, Glioma, Insulin signaling pathway, Jak-STAT signaling pathway, Leukocyte transendothelial migration, Melanoma, mTOR signaling pathway, Natural killer cell mediated cytotoxicity, Neurotrophin signaling pathway, Non-small cell lung cancer, Pancreatic cancer, Pathways in cancer, Phosphatidylinositol signaling system, Progesterone-mediated oocyte maturation, Prostate cancer, Regulation of actin cytoskeleton, Renal cell carcinoma, Small cell lung cancer, T cell receptor signaling pathway, Toll-like receptor signaling pathway, Type II diabetes mellitus, VEGF signaling pathway
• Gene Summary: Phosphatidylinositol 3-kinase (PI3K) phosphorylates phosphatidylinositol and similar compounds, which then serve as second messengers in growth signaling pathways. PI3K is composed of a catalytic and a regulatory subunit. The protein encoded by this gene represents a regulatory subunit of PI3K. The encoded protein contains two SH2 domains through which it binds activated protein tyrosine kinases to regulate their activity. [provided by RefSeq, Jun 2016]
  Transcript Variant: This variant (4) contains an alternate exon and uses an alternate splice site in the 5' coding region. These differences cause translation initiation at an upstream start codon compared to variant 1. The encoded isoform (3) has a longer N-terminus than isoform 1.