LILRB2 (NM_001278404) Human Untagged Clone

CAT#: SC336381

LILRB2 (untagged) - Human leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2 (LILRB2), transcript variant 4


  "NM_001278404" in other vectors (1)

Reconstitution Protocol

USD 480.00

2 Weeks*

Size
    • 10 ug

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Specifications

Product Data
Type Human Untagged Clone
Tag Tag Free
Symbol LILRB2
Synonyms CD85D; ILT-4; ILT4; LIR-2; LIR2; MIR-10; MIR10
Vector pCMV6-Entry
E. coli Selection Kanamycin (25 ug/mL)
Mammalian Cell Selection Neomycin
Sequence Data
>NCBI ORF sequence for NM_001278404, the custom clone sequence may differ by one or more nucleotides


ATGACAGGAGCCTACCCAAAACCCACCCTCTCAGCCCAGCCCAGCCCTGTGGTGACCTCAGGAGGAAGGG
TGACCCTCCAGTGTGAGTCACAGGTGGCATTTGGCGGCTTCATTCTGTGTAAGGAAGGAGAAGATGAACA
CCCACAATGCCTGAACTCCCAGCCCCATGCCCGTGGGTCGTCCCGCGCCATCTTCTCCGTGGGCCCCGTG
AGCCCGAATCGCAGGTGGTCGCACAGGTGCTATGGTTATGACTTGAACTCTCCCTATGTGTGGTCTTCAC
CCAGTGATCTCCTGGAGCTCCTGGTCCCAGGTGTTTCTAAGAAGCCATCACTCTCAGTGCAGCCGGGTCC
TGTCATGGCCCCTGGGGAAAGCCTGACCCTCCAGTGTGTCTCTGATGTCGGCTATGACAGATTTGTTCTG
TACAAGGAGGGGGAACGTGACCTTCGCCAGCTCCCTGGCCGGCAGCCCCAGGCTGGGCTCTCCCAGGCCA
ACTTCACCCTGGGCCCTGTGAGCCGCTCCTACGGGGGCCAGTACAGATGCTACGGTGCACACAACCTCTC
CTCTGAGTGCTCGGCCCCCAGCGACCCCCTGGACATCCTGATCACAGGACAGATCCGTGGCACACCCTTC
ATCTCAGTGCAGCCAGGCCCCACAGTGGCCTCAGGAGAGAACGTGACCCTGCTGTGTCAGTCATGGCGGC
AGTTCCACACTTTCCTTCTGACCAAGGCGGGAGCAGCTGATGCCCCACTCCGTCTAAGATCAATACACGA
ATATCCTAAGTACCAGGCTGAATTCCCCATGAGTCCTGTGACCTCAGCCCACGCGGGGACCTACAGGTGC
TACGGCTCACTCAACTCCGACCCCTACCTGCTGTCTCACCCCAGTGAGCCCCTGGAGCTCGTGGTCTCAG
GACCCTCCATGGGTTCCAGCCCCCCACCCACCGGTCCCATCTCCACACCTGCAGGCCCTGAGGACCAGCC
CCTCACCCCCACTGGGTCGGATCCCCAAAGTGGTCTGGGAAGGCACCTGGGGGTTGTGATCGGCATCTTG
GTGGCCGTCGTCCTACTGCTCCTCCTCCTCCTCCTCCTCTTCCTCATCCTCCGACATCGACGTCAGGGCA
AACACTGGACATCGACCCAGAGAAAGGCTGATTTCCAACATCCTGCAGGGGCTGTGGGGCCAGAGCCCAC
AGACAGAGGCCTGCAGTGGAGGTCCAGCCCAGCTGCCGACGCCCAGGAAGAAAACCTCTATGCTGCCGTG
AAGGACACACAGCCTGAAGATGGGGTGGAGATGGACACTCGGGCTGCTGCATCTGAAGCCCCCCAGGATG
TGACCTACGCCCAGCTGCACAGCTTGACCCTCAGACGGAAGGCAACTGAGCCTCCTCCATCCCAGGAAAG
GGAACCTCCAGCTGAGCCCAGCATCTACGCCACCCTGGCCATCCACTAG


Restriction Sites SgfI-MluI     
ACCN NM_001278404
ORF Size 1449 bp
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Reference Data
RefSeq NM_001278404.2, NP_001265333.2
RefSeq Size 2789
RefSeq ORF 1449
Locus ID 10288
Protein Families Transmembrane
Gene Summary This gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. The encoded protein belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). The receptor is expressed on immune cells where it binds to MHC class I molecules on antigen-presenting cells and transduces a negative signal that inhibits stimulation of an immune response. It is thought to control inflammatory responses and cytotoxicity to help focus the immune response and limit autoreactivity. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Transcript Variant: This variant (4) lacks a portion of the 5' coding region, and uses a downstream in-frame start codon, compared to variant 1. The encoded isoform (3) has a shorter N-terminus, compared to isoform 1.

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.