INSC (NM_001278316) Human Untagged Clone

CAT#: SC336423

INSC (untagged) - Human inscuteable homolog (Drosophila) (INSC), transcript variant 6

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: INSC
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_001278316, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGATGGCACTGCCTGGAGGTCGCCACCTGGACTCCGTCACCCTGCCGGGTCAGCGGCTACACCTGATGC
  AGGTGGACTCAGTCCAGCGCTGGATGGAAGATCTGAAGCTCATGACCGAGTGCGAGTGCATGTGTGTCCT
  GCAGGCCAAGCCCATCAGCCTGGAAGAGGATGCACAGGGTGACCTCATCCTGGCAGGTGGCCCTGGCCCT
  GGAGACCCCCTGCAGCTGCTGCTCAAACGGGGTTGGGTCATTAGCACAGAGCTGCGCAGGATCGGGCAGA
  AGCTGGCCCAGGACCGCTGGGCACGGGTGCACAGCATGAGCGTGCGTCTGACCTGCCATGCCCGCTCCAT
  GGTCAGCGAGTACAGTGCTGTCAGCAGGAACTCCTTGAAGGAAATGGGCGAGATTGAGAAGCTGCTAATG
  GAGAAATGCTCGGAGCTCTCGGCAGTCACAGAGAGGTGCCTTCAGGTTGAGAATGAGCATGTCCTGAAGT
  CAATGAAGGCCTGCGTGAGTGAGACCCTGAGCATGCTGGGCCAGCACTTTGGTCAGCTGCTGGAGCTGGC
  CCTGACACGGGAGGTTCAGGCACTGGTGAGAAAAATTGATGCCTCAGACAATATCTACACCACAGAGTCC
  ACCACAGGGAACCTGTTCAGCCTGACCCAGGAGGGGGCTCCCTTGTGCCGCATCATAGCCAAGGTGGATG
  GCGTTCTGTGCTTGGCCGACATCCTGACCGACAACAGCCACTCAGAGGCCACACGGGCTGAGGCTGCGGC
  TGTGGTGGCCCAGGTCACCTCCCCACACCTGCCCGTCACCCAGCACCTCAGTAGCTTCCTGGAGAGCATG
  GAGGAGATCGTGACAGCCCTCGTCAAACTGTGCCAAGAGGCCTCATCAGGGGAAGTCTTCCTACTGGCCT
  CTGCGGCCCTTGCCAACATCACGTTCTTTGACACAATGGCCTGCGAGATGCTCCTGCAGTTGAATGCCAT
  CCGTGTTCTCCTGGAAGCCTGCAGTGACAAGCAGAGAGTGGACACGCCTTACACTCGGGACCAGATTGTG
  ACCATCTTGGCAAACATGTCTGTCCTAGAACAGTGTGCCTCTGACATCATTCAGGAAAATGGGGTCCAGC
  TTATCATGGGCATGCTGTCTGAAAAACCAAGGTCTGGGACTCCTGCTGAAGTGGCAGCCTGTGAGCGAGT
  CCAGCAGAAAGCTGCAGTGACCCTGGCTCGTCTCAGCCGAGACCCAGATGTGGCACGGGAGGCCGTGCGG
  CTCAGCTGCATGTCCCGTCTCATCGAGCTCTGCAGATCCCCATCAGAGAGGAACAGCAGTGACGCCGTGC
  TTGTGGCCTGCCTGGCTGCTCTGCGTAGATTGGCTGGGGTCTGCCCTGAAGGCCTCCAGGACTCTGACTT
  TCAGCAGTTGGTCCAGCCTCGGCTGGTGGACTCCTTCTTACTCTGCAGCAACATGGAGGAGAGTTTTGTG
  TAG
  
  
• Restriction Sites: SgfI-MluI
• ACCN: NM_001278316
• ORF Size: 1473 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_001278316.1, NP_001265245.1
• RefSeq Size: 2730
• RefSeq ORF: 1473
• Locus ID: 387755
• Gene Summary: In Drosophila, neuroblasts divide asymmetrically into another neuroblast at the apical side and a smaller ganglion mother cell on the basal side. Cell polarization is precisely regulated by 2 apically localized multiprotein signaling complexes that are tethered by Inscuteable, which regulates their apical localization (Izaki et al., 2006 [PubMed 16458856]). [supplied by OMIM, Mar 2008]
  Transcript Variant: This variant (6) differs in the 5' UTR and has multiple coding region differences, compared to variant 1. The resulting isoform (e) is shorter at the N-terminus and lacks an internal segment, compared to isoform a.