PXK (NM_001289098) Human Untagged Clone

CAT#: SC336561

PXK (untagged) - Human PX domain containing serine/threonine kinase (PXK), transcript variant 4

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: PXK
• Synonyms: MONAKA; SLOB
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_001289098, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGGCCTTCATGGAGAAGCCGCCAGCCGGCAAGGTGCTGCTGGACGACACGGTGCCGCTGACAGCAGCCA
  TCGAGGCGAGCCAGAGCCTGCAGTCCCACACGGAATATATTATTCGAGTGCAAAGAGGAATTTCTGTGGA
  AAACAGCTGGCAGATTGTTAGAAGATACAGTGACTTTGATTTGCTTAACAACAGCTTACAGATTGCAGGC
  CTAAGTCTACCTCTTCCTCCCAAAAAATTGATTGGTAACATGGATCGTGAATTCATAGCTGAAAGGCAGA
  AAGGTCTTCAGAACTATCTCAACGTGATCACAACAAATCATATCTTGTCTAATTGTGAGCTGGTTAAGAA
  GTTTTTAGATCCAAACAACTATTCCGCAAACTATACTGAGATTGCCTTGCAACAGGTTTCCATGTTCTTC
  CGATCAGAACCAAAGTGGGAGGTGGTGGAACCTTTGAAAGACATAGGTTGGAGAATAAGGAAGAAATATT
  TCTTGATGAAGATTAAAAATCAGCCAAAGGAACGGCTAGTGTTAAGCTGGGCTGACCTTGGCCCAGACAA
  GTATTTGTCAGATAAAGATTTTCAGTGTCTAATCAAACTTCTGCCTTCTTGTTTGCACCCTTACATCTAT
  CGGGTTACCTTTGCCACAGCTAATGAATCCTCAGCGTTGCTAATTAGGATGTTTAACGAAAAGGGAACAT
  TGAAGGATCTGATCTACAAGGCAAAACCAAAAGACCCATTTCTAAAGAAGTACTGCAACCCTAAGAAGAT
  TCAGGGCCTGGAACTCCAGCAAATAAAAACATATGGACGGCAAATATTAGAGGTACTGAAGTTTCTTCAT
  GACAAGGGATTCCCTTATGGGCATCTTCACGCCTCCAATGTGATGCTCGATGGGGACACTTGCCGGCTGC
  TGGACCTTGAGAATTCCTTATTGGGCCTGCCTTCCTTCTACCGATCTTATTTTTCACAATTCAGGAAAAT
  CAATACATTGGAAAGTGTGGATGTCCACTGCTTTGGCCACTTACTGTATGAAATGACTTATGGACGACCG
  CCAGACTCGGTGCCTGTGGACTCCTTCCCTCCTGCCCCGTCCATGGCTGTGGTGGCCGTGTTGGAGTCTA
  CGCTGTCTTGTGAAGCCTGTAAAAATGGCATGCCTACCATCTCCCGGCTCTTACAGATGCCATTATTCAG
  CGATGTTTTACTAACCACTTCTGAAAAACCACAGTTTAAGATCCCTACAAAGTTAAAAGAGGCATTGAGA
  ATTGCCAAAGAATGTATAGAGAAGAGACTAATTGAGGAACAGAAACAGATTCACCAGCATCGAAGACTGA
  CAAGAGCTCAGTCCCACCATGGATCTGAGGAGGAAAGAAAAAAAAGAAAGATTTTAGCTCGAAAGAAGTC
  AAAACGATCTGCTCTTGAAAATAGTGAAGAGCATTCAGCGAAGTACAGCAACTCCAATAATTCAGCAGGA
  TCTGGGGCCAGCTCACCTCTCACGTCCCCGTCATCGCCAACTCCACCCTCTACATCAGTAGAGCATGCAC
  CATTTTGA
  
  
• Restriction Sites: SgfI-MluI
• ACCN: NM_001289098
• ORF Size: 1548 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_001289098.1, NP_001276027.1
• RefSeq Size: 3053
• RefSeq ORF: 1548
• Locus ID: 54899
• Protein Families: Druggable Genome, Protein Kinase
• Gene Summary: This gene encodes a phox (PX) domain-containing protein which may be involved in synaptic transmission and the ligand-induced internalization and degradation of epidermal growth factors. Variations in this gene may be associated with susceptibility to systemic lupus erythematosus (SLE). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014]
  Transcript Variant: This variant (4) contains an alternate exon in the 3' region, resulting in an early stop codon, compared to variant 1. It encodes isoform d (also known as isoform 4), which is shorter and has a distinct C-terminus, compared to isoform a. Variants 4 and 8 both encode the same isoform (d).