STIP1 (NM_001282653) Human Untagged Clone

CAT#: SC336588

STIP1 (untagged) - Human stress-induced phosphoprotein 1 (STIP1), transcript variant 3

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: STIP1
• Synonyms: HEL-S-94n; HOP; IEF-SSP-3521; P60; STI1; STI1L
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_001282653, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGGAGCAGGTCAATGAGCTGAAGGAGAAAGGCAACAAGGCCCTGAGCGTGGGTAACATCGATGATGCCT
  TACAGTGCTACTCCGAAGCTATTAAGCTGGATCCCCACAACCACGTGCTGTACAGCAACCGTTCTGCTGC
  CTATGCCAAGAAAGGAGACTACCAGAAGGCTTATGAGGATGGCTGCAAGACTGTCGACCTAAAGCCTGAC
  TGGGGCAAGGGCTTAAAACACGAGGCAAATAACCCTCAACTGAAAGAGGGTTTACAGAATATGGAGGCCA
  GGTTGGCAGAGAGAAAATTCATGAACCCTTTCAACATGCCTAATCTGTATCAGAAGTTGGAGAGTGATCC
  CAGGACAAGGACACTACTCAGTGATCCTACCTACCGGGAGCTGATAGAGCAGCTACGAAACAAGCCTTCT
  GACCTGGGCACGAAACTACAAGATCCCCGGATCATGACCACTCTCAGCGTCCTCCTTGGGGTCGATCTGG
  GCAGTATGGATGAGGAGGAAGAGATTGCAACACCTCCACCACCACCCCCTCCCAAAAAGGAGACCAAGCC
  AGAGCCAATGGAAGAAGATCTTCCAGAGAATAAGAAGCAGGCACTGAAAGAAAAAGAGCTGGGGAACGAT
  GCCTACAAGAAGAAAGACTTTGACACAGCCTTGAAGCATTACGACAAAGCCAAGGAGCTGGACCCCACTA
  ACATGACTTACATTACCAATCAAGCAGCGGTATACTTTGAAAAGGGCGACTACAATAAGTGCCGGGAGCT
  TTGTGAGAAGGCCATTGAAGTGGGGAGAGAAAACCGAGAAGACTATCGACAGATTGCCAAAGCATATGCT
  CGAATTGGCAACTCCTACTTCAAAGAAGAAAAGTACAAGGATGCCATCCATTTCTATAACAAGTCTCTGG
  CAGAGCACCGAACCCCAGATGTGCTCAAGAAATGCCAGCAGGCAGAGAAAATCCTGAAGGAGCAAGAGCG
  GCTGGCCTACATAAACCCCGACCTGGCTTTGGAGGAGAAGAACAAAGGCAACGAGTGTTTTCAGAAAGGG
  GACTATCCCCAGGCCATGAAGCATTATACAGAAGCCATCAAAAGGAACCCGAAAGATGCCAAATTATACA
  GCAATCGAGCTGCCTGCTACACCAAACTCCTGGAGTTCCAGCTGGCACTCAAGGACTGTGAGGAATGTAT
  CCAGCTGGAGCCGACCTTCATCAAGGGTTATACACGGAAAGCCGCTGCGCTGGAAGCGATGAAGGACTAC
  ACCAAAGCCATGGATGTGTACCAGAAGGCGCTAGACCTGGACTCCAGCTGTAAGGAGGCGGCAGACGGCT
  ACCAGCGCTGTATGATGGCGCAGTACAACCGGCACGACAGCCCCGAAGATGTGAAGCGACGAGCCATGGC
  CGACCCTGAGGTGCAGCAGATCATGAGTGACCCAGCCATGCGCCTTATCCTGGAACAGATGCAGAAGGAC
  CCCCAGGCACTCAGCGAACACTTAAAGAATCCTGTAATAGCACAGAAGATCCAGAAGCTGATGGATGTGG
  GTCTGATTGCAATTCGGTGA
  
  
• Restriction Sites: SgfI-MluI
• ACCN: NM_001282653
• ORF Size: 1560 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_001282653.1, NP_001269582.1
• RefSeq Size: 2147
• RefSeq ORF: 1560
• Locus ID: 10963
• Protein Families: Stem cell - Pluripotency
• Protein Pathways: Prion diseases
• Gene Summary: STIP1 is an adaptor protein that coordinates the functions of HSP70 (see HSPA1A; MIM 140550) and HSP90 (see HSP90AA1; MIM 140571) in protein folding. It is thought to assist in the transfer of proteins from HSP70 to HSP90 by binding both HSP90 and substrate-bound HSP70. STIP1 also stimulates the ATPase activity of HSP70 and inhibits the ATPase activity of HSP90, suggesting that it regulates both the conformations and ATPase cycles of these chaperones (Song and Masison, 2005 [PubMed 16100115]). [supplied by OMIM, Jul 2009]
  Transcript Variant: This variant (3) uses an alternate 5' terminal exon and thus differs in the 5' UTR and 5' coding region, uses an alternate start codon, and contains an in-frame splice site in the 5' coding region, compared to variant 1. The encoded isoform (c) has a distinct N-terminus and is shorter than isoform a.