VPS33B (NM_001289149) Human Untagged Clone

CAT#: SC336612

VPS33B (untagged) - Human vacuolar protein sorting 33 homolog B (yeast) (VPS33B), transcript variant 3

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: VPS33B
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_001289149, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGCGATACATTGCCAGTCTTGTCAATGCTGACAAATTGGCTGGCCGAACTCGCAAATACAAAGTGATCT
  TCAGCCCTCAAAAGTTCTATGCGTGTGAGATGGTGCTTGAGGAAGAGGGAATCTATGGAGATGTGAGCTG
  TGATGAATGGGCCTTCTCTTTGCTGCCTCTTGATGTGGATCTGCTGAGCATGGAACTACCAGAATTTTTC
  AGGGATTACTTTCTGGAAGGAGATCAGCGTTGGATCAACACTGTAGCTCAGGCCTTACACCTTCTCAGCA
  CTCTCTATGGACCCTTTCCAAACTGCTATGGAATTGGCAGGTGCGCCAAGATGGCATATGAATTGTGGAG
  GAACCTGGAGGAGGAGGAGGATGGCGAAACCAAGGGCCGAAGGCCAGAGATTGGACATATCTTTCTCTTG
  GACAGAGATGTGGACTTTGTGACAGCACTTTGCTCCCAAGTGGTTTATGAGGGCCTAGTAGATGACACCT
  TCCGCATCAAGTGTGGGAGTGTCGACTTTGGCCCAGAAGTCACATCCTCTGACAAGAGCCTGAAGGTGCT
  ACTCAATGCCGAGGACAAGGTGTTTAATGAGATTCGGAACGAGCACTTCTCCAATGTCTTTGGCTTCTTG
  AGCCAGAAGGCCCGGAACTTGCAGGCCCAGTATGATCGCCGGAGAGGCATGGACATTAAGCAGATGAAGA
  ATTTCGTGTCCCAGGAGCTCAAGGGCCTGAAACAGGAGCACCGCCTGCTGAGTCTCCATATTGGGGCCTG
  TGAATCCATCATGAAGAAGAAAACCAAGCAGGATTTCCAGGAGCTAATCAAGACTGAGCATGCACTGCTA
  GAGGGGTTCAACATCCGGGAGAGCACCAGCTACATTGAGGAACACATAGACCGGCAGGTGTCGCCTATAG
  AAAGCCTGCGCCTCATGTGCCTTTTGTCCATCACTGAGAATGGTTTGATCCCCAAGGATTACCGATCTCT
  GAAAACACAGTATCTGCAGAGCTATGGCCCTGAGCACCTGCTAACCTTCTCCAATCTGCGAAGAGCTGGG
  CTCCTAACGGAGCAGGCCCCCGGGGACACCCTCACAGCCGTGGAGAGTAAAGTGAGCAAGCTGGTGACCG
  ACAAGGCTGCAGGAAAGATTACTGATGCCTTCAGTTCTCTGGCCAAGAGGAGCAATTTTCGTGCCATCAG
  CAAAAAGCTGAATTTGATCCCACGTGTGGACGGCGAGTATGATCTGAAAGTGCCCCGAGACATGGCTTAC
  GTCTTCGGTGGTGCTTATGTGCCCCTGAGCTGCCGAATCATTGAGCAGGTGCTAGAGCGGCGAAGCTGGC
  AGGGCCTTGATGAGGTGGTACGGCTGCTCAACTGCAGTGACTTTGCATTCACAGATATGACTAAGGAAGA
  CAAGGCTTCCAGTGAGTCCCTGCGCCTCATCTTGGTGGTGTTCTTGGGTGGTTGTACATTCTCTGAGATC
  TCAGCCCTCCGGTTCCTGGGCAGAGAGAAAGGCTACAGGTTCATTTTCCTGACGACAGCAGTCACAAACA
  GCGCTCGCCTTATGGAGGCCATGAGTGAGGTGAAAGCCTGA
  
  
• Restriction Sites: SgfI-MluI
• ACCN: NM_001289149
• ORF Size: 1581 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_001289149.1, NP_001276078.1
• RefSeq Size: 2733
• RefSeq ORF: 1581
• Locus ID: 26276
• Gene Summary: Vesicle mediated protein sorting plays an important role in segregation of intracellular molecules into distinct organelles. Genetic studies in yeast have identified more than 40 vacuolar protein sorting (VPS) genes involved in vesicle transport to vacuoles. This gene is a member of the Sec-1 domain family, and encodes the human ortholog of rat Vps33b which is homologous to the yeast class C Vps33 protein. The mammalian class C vacuolar protein sorting proteins are predominantly associated with late endosomes/lysosomes, and like their yeast counterparts, may mediate vesicle trafficking steps in the endosome/lysosome pathway. Mutations in this gene are associated with arthrogryposis-renal dysfunction-cholestasis syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014]
  Transcript Variant: This variant (3) differs in its 5' UTR and uses a downstream start codon, compared to variant 1. The encoded isoform (3) has a shorter N-terminus, compared to isoform 1.