VPS45A (VPS45) (NM_001279354) Human Untagged Clone

CAT#: SC336654

VPS45 (untagged) - Human vacuolar protein sorting 45 homolog (S. cerevisiae) (VPS45), transcript variant 3

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: VPS45
• Synonyms: H1; H1VPS45; SCN5; VPS45A; VPS45B; VPS54A; VSP45; VSP45A
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_001279354, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGGTATACACACAATCGGAGATTCTACAGAAGGAAGTGTACCTCTTTGAACGCATTGATTCTCAAAATC
  GAGAGATCATGAAACACCTGAAGGCAATTTGTTTTCTTCGACCTACAAAGGAGAATGTGGATTATATTAT
  TCAGGAGCTCCGAAGACCCAAATACACTATATATTTCATTTATTTCAGTAATGTGATCAGCAAGAGTGAC
  GTGAAGTCATTGGCTGAAGCTGATGAACAGGAAGTTGTGGCTGAGGTTCAGGAATTTTATGGTGATTACA
  TTGCTGTGAACCCACATTTGTTTTCCCTCAATATTTTGGGTTGCTGCCAGGGTCGAAATTGGGATCCAGC
  CCAGCTATCTAGAACAACTCAAGGGCTTACAGCTCTCCTTTTATCTCTGAAGAAGTGTCCCATGATTCGT
  TATCAGCTCTCATCAGAGGCAGCAAAGAGACTTGCAGAGTGCGTTAAGCAAGTGATAACTAAAGAATATG
  AACTGTTTGAATTCCGTCGGACAGAGGTTCCTCCATTGCTCCTTATTTTAGATCGCTGTGATGATGCCAT
  CACCCCATTGCTAAACCAGTGGACATATCAGGCCATGGTCCACGAACTACTAGGCATAAACAACAATCGG
  ATTGATCTTTCCAGAGTGCCGGGAATCAGTAAAGACTTAAGAGAAGTGGTCCTATCTGCTGAAAATGATG
  AATTCTATGCTAATAATATGTACCTGAACTTTGCTGAGATTGGTAGCAATATAAAGAATCTCATGGAAGA
  TTTTCAGAAGAAGAAACCAAAAGAACAGCAAAAACTAGAATCAATAGCAGACATGAAGGCGTTTGTTGAG
  AATTATCCACAGTTCAAGAAAATGTCTGGGACTGTTTCAAAGCATGTGACAGTGGTTGGAGAACTGTCTC
  GATTGGTCAGTGAACGGAATCTGCTGGAGGTTTCAGAGGTTGAGCAAGAACTGGCCTGTCAAAATGACCA
  TTCTAGTGCTCTCCAGAATATAAAAAGGCTTCTGCAGAACCCCAAAGTGACAGAGTTTGATGCTGCCCGC
  CTGGTGATGCTTTATGCTTTACATTATGAGCGACACAGCAGCAATAGCCTGCCAGGACTAATGATGGACC
  TCAGGAATAAAGGTGTTTCTGAGAAGTATCGAAAGCTCGTGTCTGCAGTTGTTGAATATGGTGGTAAACG
  AGTCAGAGGAAGTGACCTCTTCAGCCCCAAAGATGCTGTGGCTATCACCAAACAATTCCTCAAAGGACTG
  AAGGGAGTAGAAAATGTATATACACAGCATCAACCTTTCCTACATGAAACCCTGGATCATCTCATCAAAG
  GAAGGCTTAAGGAAAACCTATATCCTTATTTAGGCCCCAGCACACTCAGAGACAGACCTCAGGATATCAT
  TGTGTTTGTAATTGGAGGAGCCACCTATGAAGAGGCTCTAACAGTTTATAACCTGAACCGCACCACTCCT
  GGAGTGAGGATTGTCCTGGGAGGCACCACAGTGCACAACACGAAAAGTTTCCTAGAGGAAGTTCTGGCTT
  CTGGACTGCACAGCCGAAGCAAGGAGAGCTCTCAAGTCACATCAAGGTCAGCGAGCAGAAGATGA
  
  
• Restriction Sites: SgfI-MluI
• ACCN: NM_001279354
• ORF Size: 1605 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_001279354.1, NP_001266283.1
• RefSeq Size: 2469
• RefSeq ORF: 1605
• Locus ID: 11311
• Protein Pathways: Endocytosis
• Gene Summary: Vesicle mediated protein sorting plays an important role in segregation of intracellular molecules into distinct organelles. Genetic studies in yeast have identified more than 40 vacuolar protein sorting (VPS) genes involved in vesicle transport to vacuoles. This gene is a member of the Sec1 domain family, and shows a high degree of sequence similarity to mouse, rat and yeast Vps45. The exact function of this gene is not known, but its high expression in peripheral blood mononuclear cells suggests a role in trafficking proteins, including inflammatory mediators. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jul 2013]
  Transcript Variant: This variant (3) has an alternate splice site in the 5' region, which results in a downstream translation start codon, compared to variant 1. The resulting isoform (3) has a shorter N-terminus, compared to isoform 1.