VPS45A (VPS45) (NM_001279353) Human Untagged Clone

CAT#: SC336687

VPS45 (untagged) - Human vacuolar protein sorting 45 homolog (S. cerevisiae) (VPS45), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: VPS45
• Synonyms: H1; H1VPS45; SCN5; VPS45A; VPS45B; VPS54A; VSP45; VSP45A
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_001279353, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGGTATACACACAATCGGAGATTCTACAGAAGGAAGTGTACCTCTTTGAACGCATTGATTCTCAAAATC
  GAGAGATCATGAAACACCTGAAGGCAATTTGTTTTCTTCGACCTACAAAGGAGAATGTGGATTATATTAT
  TCAGGAGCTCCGAAGACCCAAATACACTATATATTTCATTTATTTCAGTAATGTGATCAGCAAGAGTGAC
  GTGAAGTCATTGGCTGAAGCTGATGAACAGGAAGTTGTGGCTGAGGTTCAGCAAGTGATAACTAAAGAAT
  ATGAACTGTTTGAATTCCGTCGGACAGAGGTTCCTCCATTGCTCCTTATTTTAGATCGCTGTGATGATGC
  CATCACCCCATTGCTAAACCAGTGGACATATCAGGCCATGGTCCACGAACTACTAGGCATAAACAACAAT
  CGGATTGATCTTTCCAGAGTGCCGGGAATCAGTAAAGACTTAAGAGAAGTGGTCCTATCTGCTGAAAATG
  ATGAATTCTATGCTAATAATATGTACCTGAACTTTGCTGAGATTGGTAGCAATATAAAGAATCTCATGGA
  AGATTTTCAGAAGAAGAAACCAAAAGAACAGCAAAAACTAGAATCAATAGCAGACATGAAGGCGTTTGTT
  GAGAATTATCCACAGTTCAAGAAAATGTCTGGGACTGTTTCAAAGCATGTGACAGTGGTTGGAGAACTGT
  CTCGATTGGTCAGTGAACGGAATCTGCTGGAGGTTTCAGAGGTTGAGCAAGAACTGGCCTGTCAAAATGA
  CCATTCTAGTGCTCTCCAGAATATAAAAAGGCTTCTGCAGAACCCCAAAGTGACAGAGTTTGATGCTGCC
  CGCCTGGTGATGCTTTATGCTTTACATTATGAGCGACACAGCAGCAATAGCCTGCCAGGACTAATGATGG
  ACCTCAGGAATAAAGGTGTTTCTGAGAAGTATCGAAAGCTCGTGTCTGCAGTTGTTGAATATGGTGGTAA
  ACGAGTCAGAGGAAGTGACCTCTTCAGCCCCAAAGATGCTGTGGCTATCACCAAACAATTCCTCAAAGGA
  CTGAAGGGAGTAGAAAATGTATATACACAGCATCAACCTTTCCTACATGAAACCCTGGATCATCTCATCA
  AAGGAAGGCTTAAGGAAAACCTATATCCTTATTTAGGCCCCAGCACACTCAGAGACAGACCTCAGGATAT
  CATTGTGTTTGTAATTGGAGGAGCCACCTATGAAGAGGCTCTAACAGTTTATAACCTGAACCGCACCACT
  CCTGGAGTGAGGATTGTCCTGGGAGGCACCACAGTGCACAACACGAAAAGAGATGGGGTTTCACTATGTT
  CCCCTGCCTGGTTTCGAACTCCTGGGCTCAAGCGATCCACCCGCCTCAGCCTCCCAAAGTGCTGGGATTA
  CAGCTTTCCTAGAGGAAGTTCTGGCTTCTGGACTGCACAGCCGAAGCAAGGAGAGCTCTCAAGTCACATC
  AAGGTCAGCGAGCAGAAGATGAAACGGTGGTTGGGGGAAGGGCACAGCTTCCTCTCTTGTCCCCACTACA
  GGTTTTCCCTACTAAACAAAGGTGTTGGAGAGCAGCTTTGGGTTCTGTGCTGGTTGTTAGAACTCATCTC
  CAGGTAG
  
  
• Restriction Sites: SgfI-MluI
• ACCN: NM_001279353
• ORF Size: 1617 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_001279353.1, NP_001266282.1
• RefSeq Size: 2367
• RefSeq ORF: 1617
• Locus ID: 11311
• Protein Pathways: Endocytosis
• Gene Summary: Vesicle mediated protein sorting plays an important role in segregation of intracellular molecules into distinct organelles. Genetic studies in yeast have identified more than 40 vacuolar protein sorting (VPS) genes involved in vesicle transport to vacuoles. This gene is a member of the Sec1 domain family, and shows a high degree of sequence similarity to mouse, rat and yeast Vps45. The exact function of this gene is not known, but its high expression in peripheral blood mononuclear cells suggests a role in trafficking proteins, including inflammatory mediators. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jul 2013]
  Transcript Variant: This variant (2) differs in the 5' UTR and has multiple differences in the coding region, compared to variant 1. The resulting isoform (2) is shorter and has a shorter N-terminus, lacks an internal segment and has a longer and distinct C-terminus, compared to isoform 1.