GAB3 (NM_001282283) Human Untagged Clone

CAT#: SC336742

GAB3 (untagged) - Human GRB2-associated binding protein 3 (GAB3), transcript variant 3

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: GAB3
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_001282283, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGAGTGCGGGCGACGCAGTGTGCACCGGCTGGCTCGTTAAGTCGCCCCCCGAGAGGAAGCTACAGCGCT
  ACGCCTGGCGCAAGCGCTGGTTTGTCCTCCGGCGAGGCCGCATGAGCGGCAACCCCGATGTCTTGGAGTA
  CTACAGGAACAAGCACTCCAGCAAGCCCATCCGGGTGATAGACCTCAGCGAGTGTGCAGTGTGGAAGCAT
  GTGGGCCCCAGCTTTGTTCGGAAGGAATTTCAGAATAATTTCGTGTTCATTGTCAAGACTACTTCCCGTA
  CATTCTACCTGGTGGCCAAAACTGAGCAAGAAATGCAGGTGTGGGTGCACAGCATCAGTCAGGTCTGCAA
  CCTTGGCCACCTGGAGGATGGTGCAGCAGATTCCATGGAGAGCCTCTCTTACACGCCCTCCTCCCTGCAG
  CCATCCTCTGCCAGCTCCCTTCTTACCGCCCATGCTGCCAGCTCCTCTTTGCCAAGAGATGACCCAAACA
  CTAATGCCGTAGCCACTGAGGAAACCAGAAGTGAGTCAGAGCTTCTCTTCCTTCCAGATTATCTGGTTTT
  GTCCAACTGCGAGACTGGAAGACTGCACCATACCAGTCTACCCACCAGATGTGATAGCTGGTCAAACTCA
  GACCGTTCATTGGAACAGGCTTCATTTGATGATGTTTTTGTTGACTGCCTGCAGCCGCTCCCCTCCAGTC
  ATTTGGTCCACCCCTCATGCCATGGCAGTGGAGCTCAGGAGGTGCCATCCTCGAGGCCTCAGGCTGCCCT
  GATCTGGAGTAGAGAAATCAATGGGCCACCCAGGGACCACTTGTCTTCTTCACCATTGCTGGAAAGTTCC
  TTAAGTTCCACCATTCAGGTAGATAAAAATCAAGGTTCCTTACCCTGTGGAGCAAAAGAACTAGACATTA
  TGTCCAACACTCCACCTCCCCGCCCCCCTAAGCCAAGCCATCTGTCTGAACGGCGCCAAGAGGAGTGGAG
  TACACACAGTGGTAGCAAGAAGCCAGAATGCACTCTGGTTCCAAGAAGAATCTCCCTCTCTGGTTTAGAC
  AACATGAGAACCTGGAAAGCTGATGTAGAAGGCCAATCCTTAAGACACCGAGACAAGCGGCTTAGTTTGA
  ATTTGCCATGCAGGTTCTCCCCGATGTACCCCACAGCTTCAGCCAGTATCGAAGACAGCTATGTGCCCAT
  GAGCCCCCAGGCTGGTGCCTCTGGTCTTGGACCCCACTGCAGCCCTGATGACTACATTCCAATGAACTCA
  GGAAGCATCTCAAGCCCGTTGCCTGAGCTGCCTGCAAACCTGGAACCTCCCCCAGTGAATAGAGATCTCA
  AGCCTCAGAGGAAATCACGGCCACCTCCTCTGGACCTGAGAAACCTCTCGATCATCCGGGAACATGCATC
  TCTTACCAGGACCCGCACTGTGCCTTGCAGTCGAACCAGCTTTCTCTCTCCAGAAAGAAATGGTATTAAT
  TCTGCAAGATTTTTTGCTAATCCTGTTTCCAGAGAAGACGAAGAAAGCTACATCGAAATGAAACTTCTCC
  TTTCAGAAGAACAAAGAGTAGACTATGTCCAAGTGGATGAGCAGAAGACACAGGCTCTCCAGAGCACAAA
  ACAGGAGTGGACGGATGAAAGGCAATCCAAAGTATGA
  
  
• Restriction Sites: SgfI-MluI
• ACCN: NM_001282283
• ORF Size: 1647 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_001282283.1, NP_001269212.1
• RefSeq Size: 4647
• RefSeq ORF: 1647
• Locus ID: 139716
• Gene Summary: This gene is a member of the GRB2-associated binding protein gene family. These proteins are scaffolding/docking proteins that are involved in several growth factor and cytokine signaling pathways, and they contain a pleckstrin homology domain, and bind SHP2 tyrosine phosphatase and GRB2 adapter protein. The protein encoded by this gene facilitates macrophage differentiation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013]
  Transcript Variant: This variant (3) lacks an in-frame exon in the 3' coding region, compared to variant 1. The encoded isoform (3) is shorter, compared to isoform 1.