EXDL1 (EXD1) (NM_001286441) Human Untagged Clone

CAT#: SC336834

EXD1 (untagged) - Human exonuclease 3'-5' domain containing 1 (EXD1), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: EXD1
• Synonyms: EXDL1
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_001286441, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGGACCCCAGCAGTGACTACCATTTCCTCAGCCAGATTTTGTGGAAGAGGGTGAAACTCACATTGGTCT
  GTGGTGTCTTCGAGGGTGTGCTTCAGCATGTTGACCCTAATAAGATTGTTGTCCTGAAGAAAGTGAAGAA
  TGTGGAGACAGGTCGAAGTGTCCCAGGAGTGAAGTTGTTTTTTGGGCATGAGATTGTGAATGTGGAACTA
  CTAGATGAAGTGGAACAAGGCTCAGTGAGAGCAAAAGCATCTTCTGTTAGTCTACATGCAGAAAGAACCT
  GGATGGAGAAAATGAAAGTTGAAGACCTAAATGTATGTGAGCCTGCTTCTCCTGCCCCTGAAGCACCAGC
  TACCTCTCTGCTGAATGACCTCAAGTACAGCCCATCAGAGGAAGAGGAGGTGACATACACAGTCATTAAT
  CAATTCCAGCAGAAGTTTGGTGCTGCGATACTCCATATCAAGAAGCAGAATGTCCTGAGTGTGGCAGCAG
  AAGGAGCGAATGTATGTCGCCATGGCAAACTGTGCTGGCTGCAGGTGGCCACAAATTGCCGAGTTTACTT
  ATTTGACATTTTCCTTCTGGGAAGTCGAGCTTTCCACAATGGACTTCAGATGATACTAGAAGACAAGAGA
  ATTTTGAAGGTTATCCATGATTGTCGTTGGCTTTCTGATTGCCTCTCTCATCAGTATGGAATTTTGCTGA
  ATAATGTCTTTGACACACAGGTAGCAGATGTACTTCAGTTTTCCATGGAAACGGGTGGCTATCTTCCAAA
  CTGCATCACTACTTTGCAGGAGAGTTTAATCAAACACCTTCAAGTAGCCCCTAAATATCTCTCCTTTCTA
  GAAAAGAGACAAAAACTAATTCAGGAAAATCCAGAAGTATGGTTCATCCGACCTGTTTCACCCTCTTTAC
  TGAAAATTTTGGCCCTGGAAGCTACCTACCTGTTACCCCTTCGCTTGGCACTCCTAGATGAGATGATGTC
  TGACCTAACCACCCTGGTGGATGGTTACCTAAACACGTATCGCGAAGGGTCTGCAGACCGGCTTGGAGGC
  ACTGAGCCTACATGTATGGAGCTGCCAGAGGAACTGCTTCAACTCAAGGACTTCCAGAAGCAGCGCAGGG
  AGAAAGCTGCAAGAGAATATAGGGTGAATGCACAGGGACTCCTGATAAGGACAGTGCTACAGCCAAAGAA
  ATTAGTGACAGAGACAGCAGGGAAAGAGGAGAAAGTCAAAGGCTTCTTATTTGGTAAAAATTTTAGGATA
  GATAAAGCTCCAAGTTTTACATCTCAAGACTTTCACGGGGATGTGAATTTACTGAAAGAAGAATCTTTGA
  ATAAACAAGCTACAAATCCTCAACATCTACCTCCCACAGAGGAAGGGGAAACCAGTGAGGATTCCAGTAA
  CAAACTCATTTGCACAAAGTCAAAGGGGTCAGAGGACCAGAGAATAACTCAGAAAGAACACTTTATGACA
  CCCAAACATGAGTTTCAGGCAAGTTTATCTTTGAAAGAGGAGACAGAACAGTTATTGATGGTGGAAAACA
  AGGAAGATTTAAAATGCACAAAACAGGCTGTTTCAATGTCTTCCTTTCCTCAGGAAACCAGAGTGTCTCC
  AAGTGACACTTTTTATCCTATCAGAAAGACTGTGGTTTCCACACTCCCTCCCTGTCCAGCCTTGGAGAAG
  ATCGATTCCTGGATAAGTCCTTTTCTAAATCTGCCCTAG
  
  
• Restriction Sites: SgfI-MluI
• ACCN: NM_001286441
• ORF Size: 1719 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_001286441.1, NP_001273370.1
• RefSeq Size: 3264
• RefSeq ORF: 1719
• Locus ID: 161829
• Gene Summary: RNA-binding component of the PET complex, a multiprotein complex required for the processing of piRNAs during spermatogenesis. The piRNA metabolic process mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposable elements, preventing their mobilization, which is essential for the germline integrity (By similarity). The PET complex is required during the secondary piRNAs metabolic process for the PIWIL2 slicing-triggered loading of PIWIL4 piRNAs. In the PET complex, EXD1 probably acts as an RNA adapter. EXD1 is an inactive exonuclease. [UniProtKB/Swiss-Prot Function]
  Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.