MARCH8 (NM_001282866) Human Untagged Clone

CAT#: SC336838

MARCH8 (untagged) - Human membrane-associated ring finger (C3HC4) 8, E3 ubiquitin protein ligase (MARCH8), transcript variant 4

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: MARCH8
• Synonyms: c-MIR; CMIR; MARCH-VIII; MIR; RNF178
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_001282866, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGAGCATGCCACTGCATCAGATCTCTGCCATTCCATCCCAGGATGCCATCTCTGCTAGAGTCTACAGAA
  GTAAGACCAAAGAAAAGGAGAGGGAAGAACAGAATGAGAAGACTTTGGGACATTTCATGAGTCATTCAAG
  CAACATTTCTAAGGCTGGGAGTCCTCCGTCAGCATCAGCTCCGGCTCCGGTGTCCTCCTTCTCTCGCACT
  TCTATCACGCCATCCAGCCAGGACATCTGCAGTTCCAGTGCAGTGTTTTCTGAGTGTTGTCACCACAGTT
  CCGTGCAGTCTGCTGTTGTCTCGAAAGCTCCTCACTGCCAGAGTTCTCTGACACAAGGGCTCACTGTGAC
  AGTTATCTGTAAGGACACATTACAGGCGTCAAAGAGAAATTCCTTTGGTTCAGAATGGGCCCAGGCCTTG
  AAGCCTGCTAAGAATACCAAAGCCAGAAGAACACTAAAGTTCTCAAGGTCCCTCAATGATGTGGGTGAGA
  AGGCGCAGGATACTTCAGAAAGTTTTGCCTATGTGGAAAGAACTTGTTCTGAAGGGAAATTAATACTCCC
  TCAAGATACGTGTCTCAGAACTAACAGGTTTCATCATAAAGAAAAAAGAACCCTGAACCACAAACCTCTT
  GGCAATTCCAAACATTCTTGTGTTTCATGCCTTTCTGCCGGTCGCTCAACTGCCTCAGAGGTGGAAGCTG
  GCAAGGGGGGCAGGCCCGGCCTGCTGCTGGAAGAGAAGGCGGATGGTGAGGCCACGTCCCGAAGCCGGCA
  ACTGCTCCAGTACCTGTTCTCACTCTCGCACGGCTTGAGCGCCAGCAGCCTGCACAGGTTCCATGAGCTG
  GAGAGCTGCGCTGCTCGCCTGCACACTGCCAAGTCCTCCAGCGGGCTGGCAGGGAGTATGGGCTTCTGCT
  CTGACGAGATGGGAGACGACGATGTCTTTGAGGACAGCACATCTGCAAAACTGAAGAGTAGGGTTCTGCG
  GGCGCCCCTCTGCTCCACGGAAAAGGACAGCGACCTGGATTGTCCTTCTCCCTTCTCTGAAAAATTACCC
  CCCATATCTCCCGTGTCCACGTCAGGGGATGTCTGCAGGATCTGCCACTGTGAAGGAGATGATGAGAGCC
  CCCTGATCACCCCCTGCCACTGCACAGGAAGCCTCCACTTCGTGCACCAGGCCTGCCTGCAGCAGTGGAT
  CAAGAGCTCCGACACGCGCTGCTGCGAGCTCTGCAAGTATGAGTTCATCATGGAGACCAAGCTGAAGCCA
  CTGAGAAAATGGGAGAAGTTGCAGATGACGTCCAGCGAGCGCAGGAAGATCATGTGCTCAGTGACATTCC
  ACGTCATTGCCATCACATGTGTGGTCTGGTCCTTGTATGTGCTCATTGACCGTACTGCTGAGGAGATCAA
  GCAGGGGCAGGCAACAGGAATCCTAGAATGGCCCTTTTGGACTAAATTGGTGGTTGTGGCCATCGGCTTC
  ACCGGAGGACTTCTTTTTATGTATGTTCAGTGTAAAGTGTATGTGCAATTGTGGAAGAGACTCAAGGCCT
  ATAATAGAGTGATCTATGTTCAAAACTGTCCAGAAACAAGCAAAAAGAATATTTTTGAAAAATCTCCACT
  AACAGAGCCCAACTTTGAAAATAAACATGGATATGGAATCTGTCATTCCGACACAAACTCTTCTTGTTGC
  ACAGAGCCTGAAGACACTGGAGCAGAAATCATTCACGTCTGA
  
  
• Restriction Sites: SgfI-MluI
• ACCN: NM_001282866
• ORF Size: 1722 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_001282866.1, NP_001269795.1
• RefSeq Size: 5658
• RefSeq ORF: 1722
• Locus ID: 220972
• Protein Families: Druggable Genome, Transmembrane
• Gene Summary: MARCH8 is a member of the MARCH family of membrane-bound E3 ubiquitin ligases (EC 6.3.2.19). MARCH enzymes add ubiquitin (see MIM 191339) to target lysines in substrate proteins, thereby signaling their vesicular transport between membrane compartments. MARCH8 induces the internalization of several membrane glycoproteins (Goto et al., 2003 [PubMed 12582153]; Bartee et al., 2004 [PubMed 14722266]). [supplied by OMIM, Apr 2010]
  Transcript Variant: This variant (4) represents the longest transcript and encodes the longer isoform (b).