NR2C2 (NM_001291694) Human Untagged Clone

CAT#: SC336925

NR2C2 (untagged) - Human nuclear receptor subfamily 2, group C, member 2 (NR2C2), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: NR2C2
• Synonyms: TAK1; TR4
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_001291694, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGACCAGCCCCTCCCCACGCATCCAGATAATCTCCACCGACTCTGCTGTAGCCTCACCTCAGCGCATTC
  AGATTGTCACAGACCAGCAGACAGGACAGAAAATCCAGATAGTCACCGCAGTGGACGCCTCCGGATCCCC
  CAAACAGCAGTTCATCCTGACCAGCCCAGATGGAGCTGGAACTGGGAAGGTGATCCTGGCTTCCCCAGAG
  ACATCCAGCGCCAAGCAACTCATATTCACCACCTCAGACAACCTCGTCCCTGGCAGGATCCAGATTGTCA
  CGGATTCTGCCTCTGTGGAGCGTTTACTGGGGAAGACGGACGTCCAGCGGCCCCAGGTGGTAGAGTACTG
  TGTGGTCTGTGGCGACAAAGCCTCCGGCCGTCACTATGGGGCTGTCAGTTGTGAAGGTTGCAAAGGTTTC
  TTCAAAAGGAGTGTGAGGAAAAATTTGACCTACAGCTGCCGGAGCAACCAAGACTGCATCATCAATAAAC
  ATCACCGGAACCGCTGTCAGTTTTGCCGGCTGAAAAAATGCTTAGAGATGGGCATGAAAATGGAATCTGT
  GCAGAGTGAACGGAAGCCCTTCGATGTGCAACGGGAGAAACCAAGCAATTGTGCTGCTTCAACTGAGAAA
  ATCTATATCCGGAAAGACCTGAGAAGTCCCCTGATAGCTACTCCCACGTTTGTGGCAGACAAAGATGGAG
  CAAGACAAACAGGTCTTCTTGATCCAGGGATGCTTGTGAACATCCAGCAGCCTTTGATACGTGAGGATGG
  TACAGTTCTCCTGGCCACGGATTCTAAGGCTGAAACAAGCCAGGGAGCTCTGGGCACACTGGCAAATGTA
  GTGACCTCCCTTGCCAACCTAAGTGAATCTTTGAACAACGGTGACACTTCAGAAATCCAGCCAGAGGACC
  AGTCTGCAAGTGAGATAACTCGGGCATTTGATACCTTAGCTAAAGCACTTAATACCACAGACAGCTCCTC
  TTCTCCAAGCTTGGCAGATGGGATAGACACCAGTGGAGGAGGGAGCATCCACGTCATCAGCAGAGACCAG
  TCGACACCCATCATTGAGGTTGAAGGCCCCCTCCTTTCAGACACACACGTCACATTTAAGCTAACAATGC
  CCAGTCCAATGCCAGAGTACCTCAACGTGCACTACATCTGTGAGTCTGCATCCCGTCTGCTTTTCCTCTC
  AATGCACTGGGCTCGGTCAATCCCAGCCTTTCAGGCACTTGGGCAGGACTGCAACACCAGCCTTGTGCGG
  GCCTGCTGGAATGAGCTCTTCACCCTCGGCCTGGCCCAGTGTGCCCAGGTCATGAGTCTCTCCACCATCC
  TGGCTGCCATTGTCAACCACCTGCAGAACAGCATCCAGGAAGATAAACTTTCTGGTGACCGGATAAAGCA
  AGTCATGGAGCACATCTGGAAGCTGCAGGAGTTCTGTAACAGCATGGCGAAGCTGGATATAGATGGCTAT
  GAGTATGCATACCTTAAAGCTATAGTTCTCTTTAGCCCCGATCATCCAGGTTTGACCAGCACAAGCCAGA
  TTGAAAAATTCCAAGAAAAGGCACAGATGGAGTTGCAGGACTATGTTCAGAAAACCTACTCAGAAGACAC
  CTACCGATTGGCCCGGATCCTCGTTCGCCTGCCGGCACTCAGGCTGATGAGCTCCAACATAACAGAAGAA
  CTTTTTTTTACTGGTCTCATTGGCAATGTTTCGATAGACAGCATAATCCCCTACATCCTCAAGATGGAGA
  CAGCAGAGTATAATGGCCAGATCACCGGAGCCAGTCTATAG
  
  
• Restriction Sites: SgfI-MluI
• ACCN: NM_001291694
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_001291694.1, NP_001278623.1
• RefSeq Size: 8428 bp
• RefSeq ORF: 1791 bp
• Locus ID: 7182
• Cytogenetics: 3p25.1
• Protein Families: Druggable Genome, Nuclear Hormone Receptor, Transcription Factors
• Gene Summary: 'This gene encodes a protein that belongs to the nuclear hormone receptor family. Members of this family act as ligand-activated transcription factors and function in many biological processes such as development, cellular differentiation and homeostasis. The activated receptor/ligand complex is translocated to the nucleus where it binds to hormone response elements of target genes. The protein encoded by this gene plays a role in protecting cells from oxidative stress and damage induced by ionizing radiation. The lack of a similar gene in mouse results in growth retardation, severe spinal curvature, subfertility, premature aging, and prostatic intraepithelial neoplasia (PIN) development. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Apr 2014]'
  Transcript Variant: This variant (2) lacks an in-frame exon in the 5' coding region compared to variant 1. The encoded isoform (2) is shorter than isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.