NADPH oxidase 4 (NOX4) (NM_001291927) Human Untagged Clone

CAT#: SC336936

NOX4 (untagged) - Human NADPH oxidase 4 (NOX4), transcript variant 5

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: NOX4
• Synonyms: KOX; KOX-1; RENOX
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_001291927, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGGGAGAGATGTGGAGGAAGAGGGAAGAGGTCATTTTCCGTGAATACAGCTTTTCTTTTTACCCTTTAA
  ACATTTTTGCTCCCTTTGTTCTTTTCCCAGATTACTTCTGTTTGCTTGGGTTCATCTGGCTCTCCATGAA
  TGTCCTGCTTTTCTGGAAAACCTTCTTGCTGTATAACCAAGGGCCAGAGTATCACTACCTCCACCAGATG
  TTGGGGCTAGGATTGTGTCTAAGCAGAGCCTCAGCATCTGTTCTTAACCTCAACTGCAGCCTTATCCTTT
  TACCCATGTGCCGAACACTCTTGGCTTACCTCCGAGGATCACAGAAGGTTCCAAGCAGGAGAACCAGGAG
  ATTGTTGGATAAAAGCAGAACATTCCATATTACCTGTGGTGTTACTATCTGTATTTTCTCAGGCGTGCAT
  GTGGCTGCCCATCTGGTGAATGCCCTCAACTTCTCAGTGAATTACAGTGAAGACTTTGTTGAACTGAATG
  CAGCAAGATACCGAGATGAGGATCCTAGAAAACTTCTCTTCACAACTGTTCCTGGCCTGACAGGGGTCTG
  CATGGTGGTGGTGCTATTCCTCATGATCACAGCCTCTACATATGCAATAAGAGTTTCTAACTATGATATC
  TTCTGGTATACTCATAACCTCTTCTTTGTCTTCTACATGCTGCTGACGTTGCATGTTTCAGGAGGGCTGC
  TGAAGTATCAAACTAATTTAGATACCCACCCTCCCGGCTGCATCAGTCTTAACCGAACCAGCTCTCAGAA
  TATTTCCTTACCAGAGTATTTCTCAGAACATTTTCATGAACCTTTCCCTGAAGGATTTTCAAAACCGGCA
  GAGTTTACCCAGCACAAATTTGTGAAGATTTGTATGGAAGAGCCCAGATTCCAAGCTAATTTTCCACAGA
  CTTGGCTTTGGATTTCTGGACCTTTGTGCCTGTACTGTGCCGAAAGACTTTACAGGTATATCCGGAGCAA
  TAAGCCAGTCACCATCATTTCGGTCATAAGTCATCCCTCAGATGTCATGGAAATCCGAATGGTCAAAGAA
  AATTTTAAAGCAAGACCTGGTCAGTATATTACTCTACATTGTCCCAGTGTATCTGCATTAGAAAATCATC
  CATTTACCCTCACAATGTGTCCAACTGAAACCAAAGCAACATTTGGGGTTCATCTTAAAATAGTAGGAGA
  CTGGACAGAACGATTTCGAGATTTACTACTGCCTCCATCTAGTCAAGACTCCGAAATTCTGCCCTTCATT
  CAATCTAGAAATTATCCCAAGCTGTATATTGATGGTCCTTTTGGAAGTCCATTTGAGGAATCACTGAACT
  ATGAGGTCAGCCTCTGCGTGGCTGGAGGCATTGGAGTAACTCCATTTGCATCAATACTCAACACCCTGTT
  GGATGACTGGAAACCATACAAGCTTAGAAGACTATACTTTATTTGGGTATGCAGAGATATCCAGTCCTTC
  CGTTGGTTTGCAGATTTACTCTGTATGTTGCATAACAAGTTTTGGCAAGAGAACAGACCTGACTATGTCA
  ACATCCAGCTGTACCTCAGTCAAACAGATGGGATACAGAAGATAATTGGAGAAAAATATCATGCACTGAA
  TTCAAGACTGTTTATAGGACGTCCTCGGTGGAAACTTTTGTTTGATGAAATAGCAAAATATAACAGAGGA
  AAAACAGTTGGTGTTTTCTGTTGTGGACCCAATTCACTATCCAAGACTCTTCATAAACTGAGTAACCAGA
  ACAACTCATATGGGACAAGATTTGAATACAATAAAGAGTCTTTCAGCTGA
  
  
• Restriction Sites: SgfI-MluI
• ACCN: NM_001291927
• ORF Size: 1800 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_001291927.1, NP_001278856.1
• RefSeq Size: 4209
• RefSeq ORF: 1800
• Locus ID: 50507
• Protein Families: Druggable Genome, Transmembrane
• Gene Summary: This gene encodes a member of the NOX-family of enzymes that functions as the catalytic subunit the NADPH oxidase complex. The encoded protein is localized to non-phagocytic cells where it acts as an oxygen sensor and catalyzes the reduction of molecular oxygen to various reactive oxygen species (ROS). The ROS generated by this protein have been implicated in numerous biological functions including signal transduction, cell differentiation and tumor cell growth. A pseudogene has been identified on the other arm of chromosome 11. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2009]
  Transcript Variant: This variant (5) differs in the 5' UTR and 5' coding region, compared to variant 1. The encoded isoform (e) has a longer and distinct N-terminus, compared to isoform a. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.