C3IP1 (KLHL12) (NM_001303051) Human Untagged Clone

CAT#: SC336960

KLHL12 (untagged) - Human kelch-like family member 12 (KLHL12), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: KLHL12
• Synonyms: C3IP1; DKIR
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_001303051, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGGACGTGAATAAATTTGAGGCCTCTGTGGGTTTTCTCGATGTCAAAAAGTTCCTCAGTACCTGGAAGT
  TGCAGAATCCAAGGACCCATTTTGTTCTTTCTCCGCACTGCTTTATGGGAGGCATTATGGCCCCCAAAGA
  CATAATGACAAATACTCATGCTAAATCCATCCTCAATTCAATGAACTCCCTCAGGAAGAGCAATACCCTC
  TGTGATGTGACATTGAGAGTAGAGCAGAAAGACTTCCCTGCCCATCGGATTGTGCTGGCTGCCTGTAGTG
  ATTACTTCTGTGCCATGTTCACTAGTGAGCTCTCAGAGAAGGGGAAACCTTATGTTGACATCCAAGGTTT
  GACTGCCTCTACCATGGAAATTTTATTGGACTTTGTGTACACAGAAACAGTACATGTGACAGTGGAGAAT
  GTACAAGAACTGCTTCCTGCAGCCTGTCTGCTTCAGTTGAAAGGTGTGAAACAAGCCTGCTGTGAGTTCT
  TAGAAAGTCAGTTGGACCCTTCTAATTGCCTGGGTATTAGGGATTTTGCTGAAACCCACAATTGTGTTGA
  CCTGATGCAAGCAGCTGAGGTTTTTAGCCAGAAGCATTTTCCTGAAGTGGTACAGCATGAAGAGTTCATT
  CTTCTGAGTCAAGGAGAGGTGGAAAAGCTAATCAAGTGCGACGAAATTCAGGTGGATTCTGAAGAGCCAG
  TCTTTGAGGCTGTCATCAACTGGGTGAAGCATGCCAAGAAAGAGCGGGAAGAATCCTTGCCTAACCTGCT
  ACAGTATGTGCGGATGCCCCTACTAACCCCCAGGTATATCACAGATGTAATAGATGCTGAGCCTTTCATC
  CGCTGTAGTTTACAATGCAGGGATCTGGTTGATGAAGCAAAGAAGTTTCATCTGAGGCCTGAACTTCGGA
  GTCAGATGCAGGGACCCAGGACAAGGGCTCGCCTAGGAGCCAATGAAGTGCTTTTGGTGGTTGGGGGCTT
  TGGAAGCCAGCAGTCTCCCATTGATGTGGTAGAGAAATATGACCCCAAGACTCAGGAGTGGAGCTTTTTG
  CCAAGCATCACTCGTAAGAGACGTTATGTGGCCTCAGTGTCCCTTCATGACCGGATCTACGTCATTGGTG
  GCTATGATGGCCGTTCCCGCCTTAGTTCAGTGGAATGTCTAGACTACACAGCAGATGAGGATGGGGTCTG
  GTATTCTGTGGCCCCTATGAATGTCCGACGAGGTCTTGCTGGAGCCACCACCCTGGGAGATATGATCTAT
  GTCTCTGGAGGCTTTGATGGAAGCAGGCGTCACACCAGTATGGAGCGCTATGATCCAAACATTGACCAGT
  GGAGCATGCTGGGAGATATGCAGACAGCCCGGGAAGGTGCCGGACTCGTAGTGGCCAGTGGAGTGATCTA
  CTGTCTAGGAGGATATGACGGCTTGAATATCTTAAATTCAGTTGAGAAATACGACCCTCATACAGGACAT
  TGGACTAATGTTACACCAATGGCCACCAAGCGTTCTGGTGCAGGAGTAGCCCTGCTGAATGACCATATTT
  ATGTGGTGGGGGGATTTGATGGTACAGCCCACCTTTCTTCCGTTGAAGCATACAACATTCGCACTGATTC
  CTGGACAACTGTCACCAGTATGACCACTCCACGATGCTATGTAGGGGCCACAGTGCTTCGGGGGAGACTC
  TATGCAATTGCAGGATATGATGGTAATTCCCTGCTAAGTAGCATTGAATGTTATGACCCTATCATCGACA
  GCTGGGAAGTCGTGACATCCATGGGAACCCAGCGCTGTGATGCTGGTGTTTGTGTTCTCCGCGAGAAGTG
  A
  
  
• Restriction Sites: SgfI-MluI
• ACCN: NM_001303051
• ORF Size: 1821 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_001303051.1, NP_001289980.1
• RefSeq Size: 3364
• RefSeq ORF: 1821
• Locus ID: 59349
• Gene Summary: This gene encodes a member of the KLHL (Kelch-like) family of proteins. This protein has been identified as an autoantigen in the autoimmune disease Sjogren's syndrome and as a potential biomarker in primary biliary cirrhosis. This protein may act as a substrate adaptor of the Cullin-3 ubiquitin ligase complex to promote substrate-specific ubiquitylation. Ubiquitylation by this complex has been shown to regulate the Wnt signaling pathway as well as COPII vesicle coat size. A pseudogene has been identified on chromosome 22. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2014]
  Transcript Variant: This variant (1) encodes the longest isoform (1).