Rho GTPase activating protein 24 (ARHGAP24) (NM_001287805) Human Untagged Clone

CAT#: SC337148

ARHGAP24 (untagged) - Human Rho GTPase activating protein 24 (ARHGAP24), transcript variant 4

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: ARHGAP24
• Synonyms: FILGAP; p73; p73RhoGAP; RC-GAP72; RCGAP72
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_001287805, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGTTTGTGCAAGGAGGCGATCGAGATCGGATGACAGCAAATCATGAAAGCTACCTCCTCATGGCAAGCA
  CCCAGAATGATATGGAAGACTGGGTGAAGTCAATCCGCCGAGTCATATGGGGACCTTTCGGAGGAGGCAT
  TTTTGGACAGAAACTGGAGGATACTGTTCGTTATGAGAAGAGATATGGGAACCGTCTGGCTCCGATGTTG
  GTGGAGCAGTGCGTGGACTTTATCCGACAAAGGGGGCTGAAAGAAGAGGGTCTCTTTCGACTGCCAGGCC
  AGGCTAATCTTGTTAAGGAGCTCCAAGATGCCTTTGACTGTGGGGAGAAGCCATCATTTGACAGCAACAC
  AGATGTACACACGGTGGCATCACTTCTTAAGCTGTACCTCCGAGAACTTCCAGAACCAGTTATTCCTTAT
  GCGAAGTATGAAGATTTTTTGTCATGTGCCAAACTGCTCAGCAAGGAAGAGGAAGCAGGTGTTAAGGAAT
  TAGCAAAGCAGGTGAAGAGTTTGCCAGTGGTAAATTACAACCTCCTCAAGTATATTTGCAGATTCTTGGA
  TGAAGTACAGTCCTACTCGGGAGTTAACAAAATGAGTGTGCAGAACTTGGCAACGGTCTTTGGTCCTAAT
  ATCCTGCGCCCCAAAGTGGAAGATCCTTTGACTATCATGGAGGGCACTGTGGTGGTCCAGCAGTTGATGT
  CAGTGATGATTAGCAAACATGATTGCCTCTTTCCCAAAGATGCAGAACTACAAAGCAAGCCCCAAGATGG
  AGTGAGCAACAACAATGAAATTCAGAAGAAAGCCACCATGGGGCAGTTACAGAACAAGGAGAACAATAAC
  ACCAAGGACAGCCCTAGTAGGCAGTGCTCCTGGGACAAGTCTGAGTCACCCCAGAGAAGCAGCATGAACA
  ATGGATCCCCCACAGCTCTATCAGGCAGCAAAACCAACAGCCCAAAGAACAGTGTTCACAAGCTAGATGT
  GTCTAGAAGCCCCCCTCTCATGGTCAAAAAGAACCCAGCCTTTAATAAGGGTAGTGGGATAGTTACCAAT
  GGGTCCTTCAGCAGCAGTAATGCAGAAGGTCTTGAGAAAACCCAAACCACCCCCAATGGGAGCCTACAGG
  CCAGAAGGAGCTCTTCACTGAAGGTATCTGGTACCAAAATGGGCACGCACAGTGTACAGAATGGAACGGT
  GCGCATGGGCATTTTGAACAGCGACACACTCGGGAACCCCACAAATGTTCGAAACATGAGCTGGCTGCCA
  AATGGCTATGTGACCCTGAGGGATAACAAGCAGAAAGAACAAGCTGGAGAGTTAGGCCAGCACAACAGAC
  TGTCCACCTATGATAATGTCCATCAACAGTTCTCCATGATGAACCTTGATGACAAGCAGAGCATTGACAG
  TGCTACCTGGTCCACTTCCTCCTGTGAAATCTCCCTCCCTGAGAACTCCAACTCCTGTCGCTCTTCTACC
  ACCACCTGCCCAGAGCAAGACTTTTTTGGGGGGAACTTTGAGGACCCTGTTTTGGATGGGCCCCCGCAGG
  ACGACCTTTCCCACCCCAGGGACTATGAAAGCAAAAGTGACCACAGGAGTGTGGGAGGTCGAAGTAGTCG
  TGCCACCAGTAGCAGTGACAACAGTGAGACATTTGTGGGCAACAGCAGCAGCAACCACAGTGCACTGCAC
  AGTTTAGTTTCCAGCCTGAAACAGGAAATGACCAAACAGAAGATAGAGTATGAGTCCAGGATAAAGAGCT
  TAGAACAGCGAAACTTGACTTTGGAAACAGAAATGATGAGCCTCCATGATGAACTGGATCAGGAGAGGAA
  AAAGTTCACAATGATAGAAATAAAAATGCGAAATGCCGAGCGAGCAAAAGAAGATGCCGAGAAAAGAAAT
  GACATGCTACAGAAAGAAATGGAGCAGTTTTTTTCCACGTTTGGAGAACTGACAGTGGAACCCAGGAGAA
  CCGAGAGAGGAAACACAATATGGATTCAGTGA
  
  
• Restriction Sites: SgfI-MluI
• ACCN: NM_001287805
• ORF Size: 1992 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_001287805.1, NP_001274734.1
• RefSeq Size: 4010
• RefSeq ORF: 1992
• Locus ID: 83478
• Gene Summary: This gene encodes a Rho-GTPase activating protein, which is specific for the small GTPase family member Rac. Binding of the encoded protein by filamin A targets it to sites of membrane protrusion, where it antognizes Rac. This results in suppression of lamellae formation and promotion of retraction to regulate cell polarity. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2016]
  Transcript Variant: This variant (4) differs in the 5' UTR and coding sequence compared to variant 1. The resulting isoform (4) has a shorter and distinct N-terminus compared to isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.