ADAM2 (NM_001278114) Human Untagged Clone

CAT#: SC337175

ADAM2 (untagged) - Human ADAM metallopeptidase domain 2 (ADAM2), transcript variant 3

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: ADAM2
• Synonyms: CRYN1; CRYN2; CT15; FTNB; PH-30b; PH30; PH30-beta
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_001278114, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGTGGCGCGTCTTGTTTCTGCTCAGCGGGCTCGGCGGGCTGCGGATGGACAGTAATTTTGATAGTTTAC
  CTGTGCAAATTACAGTTCCGGAGAAAATACGGTCAATAATAAAGGAAGGAATTGAATCGCAGGCATCCTA
  CAAAATTGTAATTGAAGGGAAACCATATACTGTGAATTTAATGCAAAAAAACTTTTTACCCCATAATTTT
  AGAGTTTACAGTTATAGTGGCACAGGAATTATGAAACCACTTGACCAAGATTTTCAGAATTTCTGCCACT
  ACCAAGGGTATATTGAAGGTTATCCAAAATCTGTGGTGATGGTTAGCACATGTACTGGACTCAGGGGCGT
  ACTACAGTTTGAAAATGTTAGTTATGGAATAGAACCCCTGGAGTCTTCAGTTGGCTTTGAACATGTAATT
  TACCAAGTAAAACATAAGAAAGCAGATGTTTCCTTATATAATGAGAAGGATATTGAATCAAGAGATCTGT
  CCTTTAAATTACAAAGCGTAGAGCCACAGCAAGATTTTGCAAAGTATATAGAAATGCATGTTATAGTTGA
  AAAACAATTGTATAATCATATGGGGTCTGATACAACTGTTGTCGCTCAAAAAGTTTTCCAGTTGATTGGA
  TTGACGAATGCTATTTTTGTTTCATTTAATATTACAATTATTCTGTCTTCATTGGAGCTTTGGATAGATG
  AAAATAAAATTGCAACCACTGGAGAAGCTAATGAGTTATTACACACATTTTTAAGATGGAAAACATCTTA
  TCTTGTTTTACGTCCTCATGATGTGGCATTTTTACTTGTTTACAGAGAAAAGTCAAATTATGTTGGTGCA
  ACCTTTCAAGGGAAGATGTGTGATGCAAACTATGCAGGAGGTGTTGTTCTGCACCCCAGAACCATAAGTC
  TGGAATCACTTGCAGTTATTTTAGCTCAATTATTGAGCCTTAGTATGGGGATCACTTATGATGACATTAA
  CAAATGCCAGTGCTCAGGAGCTGTCTGCATTATGAATCCAGAAGCAATTCATTTCAGTGGTGTGAAGATC
  TTTAGTAACTGCAGCTTCGAAGACTTTGCACATTTTATTTCAAAGCAGAAGTCCCAGTGTCTTCACAATC
  AGCCTCGCTTAGATCCTTTTTTCAAACAGCAAGCAGTGTGTGGTAATGCAAAGCTGGAAGCAGGAGAGGA
  GTGTGACTGTGGGACTGAACAGGATTGTGCCCTTATTGGAGAAACATGCTGTGATATTGCCACATGTAGA
  TTTAAAGCCGGTTCAAACTGTGCTGAAGGACCATGCTGCGAAAACTGTCTATTTATGTCAAAAGAAAGAA
  TGTGTAGGCCTTCCTTTGAAGAATGCGACCTCCCTGAATATTGCAATGGATCATCTGCATCATGCCCAGA
  AAACCACTATGTTCAGACTGGGCATCCGTGTGGACTGAATCAATGGATCTGTATAGATGGAGTTTGTATG
  AGTGGGGATAAACAATGTACAGACACATTTGGCAAAGAAGTAGAGTTTGGCCCTTCAGAATGTTATTCTC
  ACCTTAATTCAAAGACTGATGTATCTGGAAACTGTGGTATAAGTGATTCAGGATACACACAGTGTGAAGT
  TTGCAGGAATCAAAGATGTGTGAGTTCTTCATACTTGGGTTATGATTGTACTACTGACAAATGCAATGAT
  AGAGGTGTATGCAATAACAAAAAGCACTGTCACTGTAGTGCTTCATATTTACCTCCAGATTGCTCAGTTC
  AATCAGATCTATGGCCTGGTGGGAGTATTGACAGTGGCAATTTTCCACCTGTAGCTATACCAGCCAGACT
  CCCTGAAAGGCGCTACATTGAGAACATTTACCATTCCAAACCAATGAGATGGCCATTTTTCTTATTCATT
  CCTTTCTTTATTATTTTCTGTGTACTGATTGCTATAATGGTGAAAGTTAATTTCCAAAGGAAAAAATGGA
  GAACTGAGGACTATTCAAGCGATGAGCAACCTGAAAGTGAGAGTGAACCTAAAGGGTAG
  
  
• Restriction Sites: SgfI-MluI
• ACCN: NM_001278114
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_001278114.1, NP_001265043.1
• RefSeq Size: 2495 bp
• RefSeq ORF: 2019 bp
• Locus ID: 2515
• Cytogenetics: 8p11.22
• Protein Families: Druggable Genome, Protease, Transmembrane
• Gene Summary: 'This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. The encoded protein is a subunit of an integral sperm membrane glycoprotein called fertilin, which plays an important role in sperm-egg interactions. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, May 2013]'
  Transcript Variant: This variant (3) uses an alternate splice site and lacks an internal exon in the coding region, compared to variant 1. The encoded isoform (3) is shorter, compared to isoform 1.