Dynein intermediate chain 1 (DNAI1) (NM_001281428) Human Untagged Clone

CAT#: SC337252

DNAI1 (untagged) - Human dynein, axonemal, intermediate chain 1 (DNAI1), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: DNAI1
• Synonyms: CILD1; DIC1; ICS1; PCD
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_001281428, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGATTCCTGCTTCTGCGAAGGCTCCCCATAAACAGCCTCATAAGCAGAGCATCAGCATAGGCAGAGGAA
  CCAGGAAGAGAGATGAAGATTCAGGGACTGAAGTGGGAGAAGGCACAGATGAATGGGCCCAATCCAAAGC
  CACAGTTAGACCCCCTGACCAGCTGGAGTTGACCGATGCGGAGTTAAAGGAGGAGTTCACTCGGATTTTG
  ACAGCCAACAACCCACACGCACCCCAGAACATTGTCAGGTACAGCTTCAAAGAAGGCACATATAAGCCTA
  TTGGCTTTGTGAACCAACTGGCAGTTCACTACACCCAGGTTGGGAACCTGATCCCCAAAGACTCAGATGA
  AGGACGGCGGCAGCATTACCGCGATGAATTAGTGGCAGTATCCTACCAAGGTTCTCAGGAGTCTGTCAAG
  GTGATTTCAGAAACAGGAAACCTCGAAGAAGACGAAGAGCCCAAGGAGTTAGAAACTGAGCCTGGGAGTC
  AAACAGATGTGCCTGCAGCTGGGGCAGCTGAAAAAGTGACTGAAGAAGAATTGATGACTCCTAAGCAGCC
  CAAGGAGAGAAAGCTCACTAACCAGTTCAACTTCAGTGAGAGGGCCTCACAGACCTACAACAACCCTGTC
  CGGGATCGAGAATGCCAGACGGAGCCTCCTCCCAGGACAAACTTTTCAGCCACAGCCAATCAGTGGGAGA
  TCTATGATGCCTATGTAGAGGAACTTGAGAAGCAGGAAAAGACCAAAGAGAAGGAGAAGGCAAAGACCCC
  AGTGGCTAAAAAATCAGGGAAGATGGCCATGAGGAAGCTGACATCTATGGAGTCTCAGACTGATGATCTC
  ATCAAATTGTCCCAAGCTGCTAAGATCATGGAGCGGATGGTCAACCAGAATACATATGATGACATTGCTC
  AAGATTTTAAGTACTATGACGATGCTGCTGATGAATACCGGGACCAGGTGGGTACCCTGCTGCCGCTCTG
  GAAGTTCCAAAATGACAAAGCCAAGCGCCTGTCCGTCACTGCCCTCTGCTGGAATCCAAAGTACAGGGAT
  CTGTTTGCAGTGGGATATGGCTCTTATGACTTCATGAAGCAGAGCCGGGGCATGCTGCTGCTCTACAGCC
  TGAAGAACCCCAGCTTCCCTGAGTACATGTTCAGCAGCAACAGCGGCGTCATGTGTCTCGACATCCACGT
  GGACCACCCCTACCTGGTGGCAGTAGGCCACTATGACGGCAACGTGGCCATTTACAACCTCAAGAAGCCC
  CACTCCCAGCCCTCCTTCTGCAGCTCAGCCAAGTCTGGCAAGCACTCAGACCCTGTGTGGCAGGTCAAGT
  GGCAGAAGGATGACATGGACCAAAACCTTAACTTCTTCTCTGTGTCATCTGACGGCAGGATTGTGTCTTG
  GACTCTCGTGAAGAGAAAGCTGGTTCACATAGATGTCATCAAGCTGAAGGTGGAAGGCAGCACCACGGAA
  GTTCCTGAGGGGTTGCAGCTGCACCCAGTGGGTTGTGGCACTGCCTTTGACTTCCACAAAGAGATTGACT
  ACATGTTCCTAGTGGGCACAGAGGAGGGAAAAATCTACAAGTGCTCTAAATCCTACTCCAGCCAATTCCT
  CGACACCTATGACGCCCACAACATGTCAGTGGACACTGTGTCCTGGAACCCATACCACACCAAGGTCTTC
  ATGTCCTGCAGCTCCGACTGGACAGTGAAGATCTGGGACCACACCATCAAGACCCCGATGTTCATCTATG
  ACCTGAACTCAGCCGTGGGTGATGTGGCCTGGGCGCCATACTCTTCTACTGTGTTCGCAGCAGTCACCAC
  AGATGGGAAGGCCCACATATTTGACTTAGCCATCAACAAGTATGAGGCCATCTGCAACCAGCCTGTGGCG
  GCCAAAAAGAACAGGCTCACCCACGTGCAGTTCAATCTCATCCACCCCATCATCATTGTGGGCGATGACC
  GTGGGCACATCATCAGCCTCAAGCTCTCACCCAATTTGCGCAAGATGCCAAAGGAAAAGAAGGGGCAGGA
  GGTGCAGAAGGGTCCAGCTGTGGAGATTGCGAAACTGGACAAACTGCTGAACCTGGTGAGGGAAGTGAAA
  ATCAAGACCTGA
  
  
• Restriction Sites: SgfI-MluI
• ACCN: NM_001281428
• ORF Size: 2112 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_001281428.1, NP_001268357.1
• RefSeq Size: 2605
• RefSeq ORF: 2112
• Locus ID: 27019
• Protein Families: Druggable Genome
• Protein Pathways: Huntington's disease
• Gene Summary: This gene encodes a member of the dynein intermediate chain family. The encoded protein is part of the dynein complex in respiratory cilia. The inner- and outer-arm dyneins, which bridge between the doublet microtubules in axonemes, are the force-generating proteins responsible for the sliding movement in axonemes. The intermediate and light chains, thought to form the base of the dynein arm, help mediate attachment and may also participate in regulating dynein activity. Mutations in this gene result in abnormal ciliary ultrastructure and function associated with primary ciliary dyskinesia and Kartagener syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]
  Transcript Variant: This variant (2) uses an alternate in-frame splice site in the central coding region, compared to variant 1. The encoded isoform (2) is longer, compared to isoform 1.